公开(公告)号：US09623440B2

公开(公告)日：2017-04-18

申请号：US13747667

申请日：2013-01-23

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Wolfgang Hofmann ,  Taghi Noormofidi ,  Doris Zahrl

IPC: B05D5/00 ,  B01L3/00 ,  G01N33/543

CPC classification number: B05D5/00 ,  B01L3/502707 ,  B01L2200/12 ,  B01L2300/0627 ,  B01L2300/161 ,  G01N33/54393

Abstract: A method for at least partially applying a hydrophilic polymer to a measurement channel of a sensor cartridge is provided, which sensor cartridge can be replaceably inserted in an analyzer. The measurement channel comprises at least one sensor element. The method comprises inserting the sensor cartridge into the analyzer, introducing an aqueous solution containing chitosan or a chitosan derivative into the measurement channel of the sensor cartridge, and following a residence time replacing the aqueous chitosan solution with a gaseous or liquid medium, wherein residues of the chitosan or chitosan derivatives remain on the inside surface of the measurement channel and hydrophilize the surface.

公开(公告)号：US20130136657A1

公开(公告)日：2013-05-30

申请号：US13747667

申请日：2013-01-23

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Wolfgang Hofmann ,  Taghi Noormofidi ,  Doris Zahrl

IPC: B05D5/00

CPC classification number: B05D5/00 ,  B01L3/502707 ,  B01L2200/12 ,  B01L2300/0627 ,  B01L2300/161 ,  G01N33/54393

Abstract: A method for at least partially applying a hydrophilic polymer to a measurement channel of a sensor cartridge is provided, which sensor cartridge can be replaceably inserted in an analyzer. The measurement channel comprises at least one sensor element. The method comprises inserting the sensor cartridge into the analyzer, introducing an aqueous solution containing chitosan or a chitosan derivative into the measurement channel of the sensor cartridge, and following a residence time replacing the aqueous chitosan solution with a gaseous or liquid medium, wherein residues of the chitosan or chitosan derivatives remain on the inside surface of the measurement channel and hydrophilize the surface.

Abstract translation: 提供了一种用于至少部分地将亲水性聚合物施加到传感器盒的测量通道的方法，该传感器盒可以可替换地插入到分析器中。 测量通道包括至少一个传感器元件。 该方法包括将传感器盒插入分析器中，将含有壳聚糖或壳聚糖衍生物的水溶液引入到传感器盒的测量通道中，并且在用气态或液体介质代替壳聚糖水溶液的停留时间之后， 壳聚糖或壳聚糖衍生物保留在测量通道的内表面上并使表面亲水化。