公开(公告)号：US20180313850A1

公开(公告)日：2018-11-01

申请号：US16027890

申请日：2018-07-05

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Dirk Block ,  Julian Braz ,  Hans-Peter Brunner ,  James Creeden ,  Hans-Joerg Loyda ,  Ursula-Henrike Wienhues-Thelen ,  Christian Zaugg

IPC: G01N33/68

CPC classification number: G01N33/6887 ,  G01N33/6893 ,  G01N2333/47 ,  G01N2333/58 ,  G01N2800/325 ,  G01N2800/52

Abstract: The present invention relates to a method for guiding heart failure treatment in a subject suffering from heart failure. The method is based on the determination of the amount of a BNP-type peptide and a cardiac troponin in a sample from said subject. Further envisaged by the present invention are kits and devices adapted to carry out the present invention. The present invention also relates to a system for guiding heart failure treatment in a subject suffering from heart failure as disclosed herein and to reagents and kits used in performing the methods disclosed herein.

公开(公告)号：US20150233945A1

公开(公告)日：2015-08-20

申请号：US14705299

申请日：2015-05-06

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Dirk Block ,  Julian Braz ,  Hans-Peter Brunner ,  James Creeden ,  Hans-Juergen Loyda ,  Ursula-Henrike Wienhues-Thelen ,  Christian Zaugg

IPC: G01N33/68

CPC classification number: G01N33/6887 ,  G01N33/6893 ,  G01N2333/47 ,  G01N2333/58 ,  G01N2800/325 ,  G01N2800/52

Abstract: The present invention relates to a method for guiding heart failure treatment in a subject suffering from heart failure. The method is based on the determination of the amount of a BNP-type peptide and a cardiac troponin in a sample from said subject. Further envisaged by the present invention are kits and devices adapted to carry out the present invention. The present invention also relates to a system for guiding heart failure treatment in a subject suffering from heart failure as disclosed herein and to reagents and kits used in performing the methods disclosed herein.

Abstract translation: 本发明涉及一种在患有心力衰竭的受试者中引导心力衰竭治疗的方法。 该方法基于来自所述受试者的样品中BNP型肽和心肌肌钙蛋白的量的测定。 本发明进一步设想的是适用于实施本发明的试剂盒和装置。 本发明还涉及用于指导本文公开的患有心力衰竭的受试者的心力衰竭治疗的系统以及用于执行本文公开的方法的试剂和试剂盒。