公开(公告)号：US20180003710A1

公开(公告)日：2018-01-04

申请号：US15673976

申请日：2017-08-10

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Herbert Andres ,  Stefan Weiser ,  Johann Karl ,  Ursula Kunert ,  Florian Grupp

IPC: G01N33/564 ,  G01N33/563 ,  G01N33/58

CPC classification number: G01N33/564 ,  G01N33/563 ,  G01N33/58 ,  G01N2333/91215 ,  G01N2800/102

Abstract: The present invention relates to a method aiding in the assessment of rheumatoid arthritis (“RA”). The method is used in assessing RA in vitro. It is practiced by analyzing biochemical markers, comprising measuring the concentration of anti-CCP and anti-PIK3CD and correlating the concentrations determined to the absence or presence of RA. The invention also relates to the use of a marker panel comprising anti-CCP and anti-PIK3CD in the diagnosis of RA and it teaches a kit for performing the method of the invention. Further the invention relates to the use of a marker panel comprising anti-CCP and anti-PIK3CD to differentiate RA from other autoimmune diseases, preferably osteoarthritis (OA).

公开(公告)号：US10094826B2

公开(公告)日：2018-10-09

申请号：US15673976

申请日：2017-08-10

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Herbert Andres ,  Stefan Weiser ,  Johann Karl ,  Ursula Kunert ,  Florian Grupp

IPC: G01N33/53 ,  G01N33/564 ,  G01N33/563 ,  G01N33/58

Abstract: Described is a method aiding in the assessment of rheumatoid arthritis (“RA”). The method is used in assessing RA in vitro. It is practiced by analyzing biochemical markers, including measuring the concentration of anti-CCP and anti-PIK 3CD and correlating the concentrations determined to the absence or presence of RA. Also disclosed is the use of a marker panel including anti-CCP and anti-PIK3CD in the diagnosis of RA and it teaches a kit for performing the method. Also described is the use of a marker panel comprising anti-CCP and anti-PIK3CD to differentiate RA from other autoimmune diseases, preferably osteoarthritis (OA).