公开(公告)号：US10775355B2

公开(公告)日：2020-09-15

申请号：US16009434

申请日：2018-06-15

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Tobias Franz ,  Uwe Kobold ,  Peter Kupser ,  Roland Thiele

IPC: G01N30/88 ,  G01N30/06 ,  G01N30/08 ,  G01N30/24 ,  G01N30/46 ,  G01N30/72 ,  G01N35/00 ,  B01D15/18 ,  G01N30/60 ,  G01N1/40 ,  G01N30/02

Abstract: A clinical diagnostic system is presented and comprises a sample preparation station for automatically preparing samples comprising analytes of interest, a liquid chromatography (LC) separation station comprising a plurality of LC channels and a sample preparation/LC interface for inputting prepared samples into the LC channels. The system further comprises a controller to assign samples to pre-defined sample preparation workflows each comprising a pre-defined sequence of sample preparation steps and requiring a pre-defined time for completion depending on the analytes. The controller further assigns an LC channel for each prepared sample depending on the analytes and plans an LC channel input sequence for inputting the prepared samples that allows analytes from different LC channels to elute in a non-overlapping LC eluate output sequence based on expected elution times. The controller further sets and initiates a start sequence that generates a prepared sample output sequence that matches the LC channel input sequence.

公开(公告)号：US20180292368A1

公开(公告)日：2018-10-11

申请号：US16009434

申请日：2018-06-15

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Tobias Franz ,  Uwe Kobold ,  Peter Kupser ,  Roland Thiele

IPC: G01N30/88 ,  G01N30/24 ,  G01N35/00 ,  G01N30/08 ,  G01N30/46 ,  G01N30/72

Abstract: A clinical diagnostic system is presented and comprises a sample preparation station for automatically preparing samples comprising analytes of interest, a liquid chromatography (LC) separation station comprising a plurality of LC channels and a sample preparation/LC interface for inputting prepared samples into the LC channels. The system further comprises a controller to assign samples to pre-defined sample preparation workflows each comprising a pre-defined sequence of sample preparation steps and requiring a pre-defined time for completion depending on the analytes. The controller further assigns an LC channel for each prepared sample depending on the analytes and plans an LC channel input sequence for inputting the prepared samples that allows analytes from different LC channels to elute in a non-overlapping LC eluate output sequence based on expected elution times. The controller further sets and initiates a start sequence that generates a prepared sample output sequence that matches the LC channel input sequence.

公开(公告)号：US08649605B2

公开(公告)日：2014-02-11

申请号：US13888567

申请日：2013-05-07

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Tobias Franz ,  Martin Gutekunst ,  Hans-Joachim Polland ,  Claudia Schiller

IPC: G06K9/46

CPC classification number: G06T7/004 ,  G01N21/9027 ,  G01N35/1016 ,  G01N2035/1018 ,  G06T7/70

Abstract: An apparatus and method for detecting foam on a liquid surface in a vessel is presented. The vessel has an upper opening surrounded by a border. The vessel can be a tube-shaped. At least one image is taken from a region suspected to contain foam in the vessel by using an image sensing device that provides corresponding image data. An automatic evaluation of the image is performed on the basis of the image data by a data processing system using an image evaluation program. The at least one image is taken from the top of the vessel through the open upper opening onto the liquid surface. The image evaluation program of the data processing system identifies foam areas and non-foam areas in the image and provides information about the presence or absence of foam areas in the image as a result of the image evaluation.

Abstract translation: 提出了一种在容器中液体表面上检测泡沫的装置和方法。 船舶有一个由边界包围的上部开口。 容器可以是管状的。 通过使用提供相应图像数据的图像感测装置，从容器中怀疑含有泡沫的区域中取出至少一个图像。 通过使用图像评估程序的数据处理系统，基于图像数据执行图像的自动评估。 至少一个图像从容器的顶部通过打开的上部开口取出到液体表面上。 数据处理系统的图像评估程序识别图像中的泡沫区域和非泡沫区域，并且作为图像评估的结果提供关于图像中泡沫区域的存在或不存在的信息。

公开(公告)号：US20130315486A1

公开(公告)日：2013-11-28

申请号：US13888567

申请日：2013-05-07

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Tobias Franz ,  Martin Gutekunst ,  Hans-Joachim Polland ,  Claudia Schiller

IPC: G06T7/00

CPC classification number: G06T7/004 ,  G01N21/9027 ,  G01N35/1016 ,  G01N2035/1018 ,  G06T7/70

Abstract: An apparatus and method for detecting foam on a liquid surface in a vessel is presented. The vessel has an upper opening surrounded by a border. The vessel can be a tube-shaped. At least one image is taken from a region suspected to contain foam in the vessel by using an image sensing device that provides corresponding image data. An automatic evaluation of the image is performed on the basis of the image data by a data processing system using an image evaluation program. The at least one image is taken from the top of the vessel through the open upper opening onto the liquid surface. The image evaluation program of the data processing system identifies foam areas and non-foam areas in the image and provides information about the presence or absence of foam areas in the image as a result of the image evaluation.

Abstract translation: 提出了一种在容器中液体表面上检测泡沫的装置和方法。 船舶有一个由边界包围的上部开口。 容器可以是管状的。 通过使用提供相应图像数据的图像感测装置，从容器中怀疑含有泡沫的区域中取出至少一个图像。 通过使用图像评估程序的数据处理系统，基于图像数据执行图像的自动评估。 至少一个图像从容器的顶部通过打开的上部开口取出到液体表面上。 数据处理系统的图像评估程序识别图像中的泡沫区域和非泡沫区域，并且作为图像评估的结果提供关于图像中泡沫区域的存在或不存在的信息。