公开(公告)号：US5168228A

公开(公告)日：1992-12-01

申请号：US700883

申请日：1991-05-10

申请人： Peter Mansfield ,  Roger J. Ordidge ,  Ronald J. Coxon

发明人： Peter Mansfield ,  Roger J. Ordidge ,  Ronald J. Coxon

IPC分类号： G01R33/54 ,  G01R33/56

CPC分类号： G01R33/4833 ,  G01R33/56

摘要： Zonal magnification of a selected area of an image produced by Echo Planar Imaging is acheived by taking images of a defined area in the presence of a selective 180.degree. R.F. control pulse so that subsequent processing produces a magnified image of the selected area with enhanced resolution.

摘要翻译： 通过回波平面成像产生的图像的选定区域的区域放大是通过在存在选择性180°R.F的情况下拍摄限定区域的图像来实现的。 控制脉冲，使得后续处理以增强的分辨率产生所选区域的放大图像。

公开(公告)号：US5162736A

公开(公告)日：1992-11-10

申请号：US642921

申请日：1991-01-18

申请人： Peter Mansfield ,  Alistair Howseman ,  Roger J. Ordidge ,  David N. Guilfoyle

发明人： Peter Mansfield ,  Alistair Howseman ,  Roger J. Ordidge ,  David N. Guilfoyle

IPC分类号： G01R33/54 ,  G01R33/561

CPC分类号： G01R33/5615 ,  G01R33/4822 ,  G01R33/5616

摘要： A nuclear magnetic resonance (NMR) method of producing a series of three or four dimensional spin parameter maps of a defined region, which spin parameter maps are displayable as a set of contiguous planar spin parameter maps with arbitrary orientation.

摘要翻译： 产生定义区域的一系列三维或四维自旋参数图的核磁共振（NMR）方法，该自旋参数图可显示为具有任意取向的一组连续的平面自旋参数图。

公开(公告)号：US5336999A

公开(公告)日：1994-08-09

申请号：US828902

申请日：1992-03-06

申请人： Peter Mansfield ,  David N. Guilfoyle ,  Roger J. Ordidge

发明人： Peter Mansfield ,  David N. Guilfoyle ,  Roger J. Ordidge

IPC分类号： A61B5/055 ,  G01R33/48 ,  G01R33/561 ,  G01R33/20

CPC分类号： G01R33/5615 ,  G01R33/5617 ,  G01R33/5618

摘要： A magnetic resonant image of an object is produced by subjecting the object to an initial slice selection to provide an active region and by subjecting the active region to a plurality of 180.degree. RF pulses and appropriate amplitude modulated x and y gradients.

摘要翻译： 物体的磁共振图像是通过对物体进行初始切片选择以提供有源区域并通过使有源区域经受多个180°RF脉冲和适当的幅度调制的x和y梯度来产生的。

公开(公告)号：US4509015A

公开(公告)日：1985-04-02

申请号：US418641

申请日：1982-09-16

申请人： Roger J. Ordidge ,  Peter Mansfield

发明人： Roger J. Ordidge ,  Peter Mansfield

IPC分类号： A61B10/00 ,  A61B5/055 ,  G01R33/48 ,  G01R33/561 ,  G01R33/08

CPC分类号： G01R33/5615 ,  G01R33/5616

摘要： This invention provides methods of investigating a body by nuclear magnetic resonance. Nuclear magnetic resonance is preferentially excited in a slice of the body and the resulting free induction decay signals are detected in the presence of a magnetic field having first and second gradients (G.sub.y, G.sub.x).In one proposed method two experiments are performed in which the phase of the first gradient (G.sub.y) reversal is opposite, and the detected signals from the two experiments are edited to obtain a set of signals, for Fourier transformation, occurring when the first gradient has one sense. Two such sets may be obtained, one for each sense of the first gradient, and the data obtained after Fourier transformation re-ordered and added.In a second proposed method the second gradient (G.sub.x) is applied only when the first gradient (G.sub.y) has a given sense, and the free induction decay signals obtained when both gradients are present, and when only the first gradient is present, are separately processed.In a third proposed method, the first gradient (G.sub.y) is temporarily removed before each reversal of its sense, and the second gradient (G.sub.x) is reversed while the first gradient is removed, the magnitude of the second gradient being controlled so that the time integral of the second gradient at the beginning of each period when the first gradient has a given sense is the same as at the end of the preceding such period, the free induction decay signals occurring when the first gradient has said given sense only being used for data retrieval.

摘要翻译： 本发明提供了通过核磁共振研究人体的方法。 核磁共振在身体的切片中被优先激发，并且在存在具有第一和第二梯度（Gy，Gx）的磁场的情况下检测所得到的自由感应衰减信号。 在一个提出的方法中，执行两个实验，其中第一梯度（Gy）反转的相位相反，并且来自两个实验的检测信号被编辑以获得用于傅里叶变换的一组信号，当第一梯度具有 一种感觉 可以获得两个这样的集合，一个用于第一梯度的每个意义，并且在傅立叶变换重新排序并添加之后获得的数据。 在第二提出的方法中，第二梯度（Gx）仅在第一梯度（Gy）具有给定意义时被应用，并且当存在两个梯度时获得的自由感应衰减信号，并且当仅存在第一梯度时，分别 处理。 在第三提出的方法中，第一梯度（Gy）在每次反转之前临时移除，并且第二梯度（Gx）在第一梯度被移除的同时被反转，第二梯度的幅度被控制，使得时间 当第一梯度具有给定意义时，在每个周期开始处的第二梯度的积分与前一个这样的周期结束时相同，当第一梯度具有给定意义时发生的自由感应衰减信号仅用于 数据检索。

公开(公告)号：USRE32748E

公开(公告)日：1988-09-13

申请号：US932572

申请日：1986-11-20

申请人： Roger J. Ordidge ,  Robert E. Gordon

发明人： Roger J. Ordidge ,  Robert E. Gordon

IPC分类号： G01N24/08

CPC分类号： G01N24/08

摘要： A method of obtaining an NMR spectrum from a sample comprising the steps of: maintaining a static magnetic field along an axis which is homogeneous over at least a small volume constituting part of a sample applying a gradient to said magnetic field which varies in one direction orthogonal to said axis while applying an rf pulse to the sample to saturate all nuclei in the said volume except for a slab lying in a plane normal to the said one direction replacing the said gradient by a second gradient to said magnetic field which varies in a second direction orthogonal to said axis and said one direction while applying an rf pulse to the sample to saturate all nuclei in the said volume except for a slab lying in a plane normal to the said second direction, whereby nuclei in a narrow column extending parallel to the said axis have their spins left undisturbed replacing the second gradient by a third gradient to said static magnetic field which varies in a direction parallel to said axis while applying an rf pulse to the sample to selectively irradiate nuclei in a small region of the said column: and finally removing the third gradient and then reading out the free induction decay signal from the selectively irradiated nuclei in the presence of the static magnetic field alone.

公开(公告)号：US4906932A

公开(公告)日：1990-03-06

申请号：US213809

申请日：1988-06-30

申请人： Roger J. Ordidge

发明人： Roger J. Ordidge

IPC分类号： G01R33/44 ,  A61B5/055 ,  A61B10/00 ,  G01R33/46 ,  G01R33/48 ,  G01R33/56

CPC分类号： G01R33/446 ,  G01R33/56

摘要： Undesired signals are eliminated using a shaped RF pulse comprising a region of random frequency components and a region of zero components to effectively eliminate signals from areas volumes or frequency bands which are not required.

公开(公告)号：US4531094A

公开(公告)日：1985-07-23

申请号：US464139

申请日：1983-02-07

申请人： Roger J. Ordidge ,  Robert E. Gordon

发明人： Roger J. Ordidge ,  Robert E. Gordon

IPC分类号： G01N24/08 ,  G01R33/08

CPC分类号： G01N24/08

摘要： A method of obtaining an NMR spectrum from a sample comprising the steps of: maintaining a static magnetic field along an axis which is homogeneous over at least a small volume constituting part of a sample applying a gradient to said magnetic field which varies in one direction orthogonal to said axis while applying an rf pulse to the sample to saturate all nuclei in the said volume except for a slab lying in a plane normal to the said one direction replacing the said gradient by a second gradient to said magnetic field which varies in a second direction orthogonal to said axis and said one direction while applying an rf pulse to the sample to saturate all nuclei in the said volume except for a slab lying in a plane normal to the said second direction, whereby nuclei in a narrow column extending parallel to the said axis have their spins left undisturbed replacing the second gradient by a third gradient to said static magnetic field which varies in a direction parallel to said axis while applying an rf pulse to the sample to selectively irradiate nuclei in a small region of the said column; and finally removing the third gradient and then reading out the free induction decay signal from the selectively irradiated nuclei in the presence of the static magnetic field alone.

摘要翻译： 从样品获得NMR光谱的方法，包括以下步骤：沿构成部分样品的至少少量体积上的均匀的静态磁场施加梯度，所述磁场在一个方向上变化正交 到所述轴线，同时向样品施加rf脉冲以饱和所述体积中的所有核，除了位于垂直于所述一个方向的平面中的平板，将所述梯度替换为所述磁场的第二梯度，所述磁场在第二 方向与所述轴和所述一个方向正交，同时向样品施加rf脉冲以饱和所述体积中的所有核，除了位于与所述第二方向垂直的平面中的平板，由此在与第 所述轴具有未旋转的旋转，将第二梯度替换为在平行于所述轴线的方向上变化的所述静态磁场的第三梯度 对样品施加rf脉冲以选择性地照射所述柱的小区域中的核; 最后除去第三梯度，然后在存在静磁场的情况下从选择性照射的核中读出自由感应衰减信号。