公开(公告)号：US20140115871A1

公开(公告)日：2014-05-01

申请号：US14125720

申请日：2012-06-07

申请人： Roland Guidat ,  Olivier Lobet ,  Pierr Woehl

发明人： Roland Guidat ,  Olivier Lobet ,  Pierr Woehl

IPC分类号： B01J19/00

CPC分类号： B01J19/0053 ,  B01J19/0093 ,  B01J2219/00015 ,  B01J2219/00824 ,  B01J2219/00831 ,  B01J2219/0086 ,  B01J2219/00873 ,  B01J2219/00995 ,  Y10T29/49

摘要： A method is disclosed for the seamless scale-up of a micro reactor process, to transfer lab test to a pilot or production unit, the process comprising the steps of using a wall material for the lab reactor with a thermal conductivity lower than 3 W/m-K, and using a wall material for the production reactor with a thermal conductivity higher than 5 W/m-K. According to one preferred embodiment, the velocity is kept constant, and the height of the channel is determined, in order to keep the volumetric heat transfer properties constant, according to the formula: wherein HG is the overall volumetric heat transfer coefficient in the pilot or production process; A B and C are constants; Dh is the hydraulic diameter of the channel in the pilot or production process; λw is the thermal conductivity of the wall in the pilot or production process; b is the empirically determined power to which the Reynolds number is raised in the equation for the Nusselt criteria (Nu=a−RebPrc) for the type of flow in the pilot or production process; h is the height of the channel in the pilot or production process; and HG0 is the overall volumetric heat transfer coefficient in the lab-scale process.

摘要翻译： 公开了一种用于微反应器过程的无缝放大以将实验室测试转移到先导或生产单元的方法，该方法包括以下步骤：使用导热率低于3W / mK，并且使用导热率高于5W / mK的生产反应器的壁材料。 根据一个优选实施例，速度保持恒定，并且确定通道的高度，以便保持体积传热性能恒定，其中HG是飞行员中的总体积传热系数，或 生产过程; A B和C是常数; Dh是先导或生产过程中通道的液压直径; λw是先导或生产过程中墙壁的导热系数; b是在试点或生产过程中的流量类型的努塞尔标准（Nu = a-RebPrc）的方程中提高雷诺数的经验确定的功率; h是飞行员或生产过程中通道的高度; HG0是实验室规模过程中的总体积传热系数。