公开(公告)号：US5236696A

公开(公告)日：1993-08-17

申请号：US858928

申请日：1992-03-27

申请人： Rolando Catiis ,  Robin S. Cabanas ,  Joseph Binshtock

发明人： Rolando Catiis ,  Robin S. Cabanas ,  Joseph Binshtock

IPC分类号： A61K8/02 ,  A61K20060101 ,  A61K8/00 ,  A61K8/19 ,  A61K8/21 ,  A61K8/24 ,  A61K8/25 ,  A61K8/26 ,  A61K8/46 ,  A61K8/73 ,  A61K9/00 ,  A61K9/06 ,  A61K9/10 ,  A61Q11/00 ,  B01J20060101 ,  B01J13/00 ,  B01J14/00

CPC分类号： A61Q11/00 ,  A61K8/02 ,  A61K8/24 ,  A61K8/73 ,  Y10S514/937 ,  Y10S514/944 ,  Y10S514/969 ,  Y10S516/924

摘要： A continuous process for preparing a paste or cream like material which comprises the steps of means for forming under non vacuum conditions at a temperature of 90.degree. F. to 120.degree. F. a first low viscosity homogenous slurry of at least one non aqueous solvent and a gelling or bodying agent; means for forming a second low viscosity homogenous slurry under non vacuum conditions at a temperature of 90.degree. F. to 130.degree. F., means for forming a low viscosity mixture of said first low viscosity slurry and said second low viscosity slurry by a high shear mixing under non vacuum conditions at a temperature of 90.degree. F. to 130.degree. F. for 0.1 to 5 seconds; means for transforming under non vacuum and non mixing conditions at a temperature of 65.degree. F. to 120.degree. F., said low viscosity mixture into a non Newtonian mixture; and means for deaerating said non Newtonian mixture under vacuum conditions for a period of less than 3 seconds to form said paste or cream like material.

公开(公告)号：US5320832A

公开(公告)日：1994-06-14

申请号：US44422

申请日：1993-04-09

申请人： Rolando M. Catiis ,  Robin S. Cabanas ,  Joseph Binshtock

发明人： Rolando M. Catiis ,  Robin S. Cabanas ,  Joseph Binshtock

IPC分类号： A61K8/02 ,  A61K20060101 ,  A61K8/00 ,  A61K8/19 ,  A61K8/21 ,  A61K8/24 ,  A61K8/25 ,  A61K8/26 ,  A61K8/46 ,  A61K8/73 ,  A61K9/00 ,  A61K9/06 ,  A61K9/10 ,  A61Q11/00 ,  B01J20060101 ,  B01J13/00 ,  B01J14/00 ,  A61K7/16 ,  A61K7/18

CPC分类号： A61Q11/00 ,  A61K8/02 ,  A61K8/24 ,  A61K8/73 ,  Y10S514/937 ,  Y10S514/944 ,  Y10S514/969 ,  Y10S516/924

摘要： A continuous process for preparing a paste or cream like material which comprises the steps of means for forming under non vacuum conditions at a temperature of 90.degree. F. to 120.degree. F. a first low viscosity homogenous slurry of at least one non aqueous solvent and a gelling or bodying agent; means for forming a second low viscosity homogenous slurry under non vacuum conditions at a temperature of 90.degree. F. to 130.degree. F., means for forming a low viscosity mixture of said first low viscosity slurry and said second low viscosity slurry by a high shear mixing under non vacuum conditions at a temperature of 90.degree. F. to 130.degree. F. for 0.1 to 5 seconds; means for transforming under non vacuum and non mixing conditions at a temperature of 65.degree. F. to 120.degree. F. said low viscosity mixture into a non Newtonian mixture; and means for deaerating said non Newtonian mixture under vacuum conditions for a period of less than 3 seconds to form said paste or cream like material.

摘要翻译： 一种用于制备糊状或膏状材料的连续方法，其包括以下步骤：在非真空条件下在90°F至120°F的温度下形成第一低粘度均匀浆液至少一种非水溶剂和 胶凝剂或凝胶剂; 用于在非真空条件下在90°F至130°F下形成第二种低粘度均匀浆料的装置，用于通过高剪切形成所述第一低粘度浆料和所述第二低粘度浆料的低粘度混合物的装置 在非真空条件下在90°F至130°F的温度下混合0.1至5秒; 用于在非真空和非混合条件下在65°F至120°F的温度下转化的装置。所述低粘度混合物变成非牛顿混合物; 以及用于在真空条件下使所述非牛顿混合物脱气少于3秒的时间的装置，以形成所述糊状或霜状材料。