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公开(公告)号：US4722344A
公开(公告)日：1988-02-02
申请号：US866606
申请日：1986-05-23
IPC分类号： A61L29/00 , A61L29/06 , A61L29/18 , C08G18/30 , C08G18/38 , C08G18/40 , C08G18/77 , G21F1/10 , A61B6/00
CPC分类号： C08G18/773 , A61L29/06 , A61L29/18 , C08G18/3802
摘要： Catheters formed from polyurethanes containing sufficient halogenated moieties in the polymer structure to make the polyurethanes radiopaque are disclosed. Such polyurethanes can be prepared by employing halogenated diols and/or halogenated diisocyanate reactants. In preferred cases, the catheters are optically transparent in addition to being radiopaque.
摘要翻译： 公开了由在聚合物结构中含有足够卤代部分的聚氨酯形成的导管，以制造不透射线的聚氨酯。 这样的聚氨酯可以通过使用卤化二醇和/或卤代二异氰酸酯反应物来制备。 在优选情况下，除了不透射线之外，导管也是光学透明的。
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2.发明授权公开(公告)号：US07989157B2
公开(公告)日：2011-08-02
申请号：US11032923
申请日：2005-01-11
CPC分类号： A01N1/02 , A01N1/0226
摘要： A method for processing biological tissue used in biological prostheses includes providing a tissue procurement solution formed from a phosphate buffered saline (PBS) solution and a chelating agent. The tissue is transferred from the tissue procurement solution and undergoes chemical fixation. The fixed tissue is then immersed in a series of fresh bioburden reduction process (BRP) solutions to extract phospholipids. The tissue procurement solution reduces the bioburden on the stored tissue and preserves tissue architecture by minimizing tissue swelling. The tissue procurement solution further reduces calcium from the incoming water and/or tissue, and inhibits enzymes that digest the collagen matrix. The serial immersion of the tissue in the fresh bioburden solutions ensures optimal extraction of phospholipids thereby mitigating subsequent calcification of the tissue.
摘要翻译： 用于处理生物假体中使用的生物组织的方法包括提供由磷酸盐缓冲盐水（PBS）溶液和螯合剂形成的组织采购溶液。 组织从组织采购溶液转移并进行化学固定。 然后将固定的组织浸入一系列新鲜的生物负载降低过程（BRP）溶液中以提取磷脂。 组织采购解决方案减少存储组织的生物负载，并通过最小化组织肿胀来保持组织结构。 组织采购解决方案进一步减少来自进入的水和/或组织的钙，并且抑制消化胶原蛋白基质的酶。 将组织连续浸入新鲜的生物负载溶液中确保磷脂的最佳提取，从而减轻随后的组织钙化。
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公开(公告)号：US07622276B2
公开(公告)日：2009-11-24
申请号：US11422576
申请日：2006-06-06
IPC分类号： G01N1/30
CPC分类号： A01N1/02 , A01N1/0226
摘要： A method for processing biological tissue used in biological prostheses includes providing a tissue procurement solution formed from a phosphate buffered saline (PBS) solution and a chelating agent. The tissue is transferred from the tissue procurement solution and undergoes chemical fixation. The fixed tissue is then immersed in a series of fresh bioburden reduction process (BRP) solutions to extract phospholipids. The tissue procurement solution reduces the bioburden on the stored tissue and preserves tissue architecture by minimizing tissue swelling. The tissue procurement solution further reduces calcium from the incoming water and/or tissue, and inhibits enzymes that digest the collagen matrix. The serial immersion of the tissue in the fresh bioburden solutions ensures optimal extraction of phospholipids thereby mitigating subsequent calcification of the tissue.
摘要翻译： 用于处理生物假体中使用的生物组织的方法包括提供由磷酸盐缓冲盐水（PBS）溶液和螯合剂形成的组织采购溶液。 组织从组织采购溶液转移并进行化学固定。 然后将固定的组织浸入一系列新鲜的生物负载降低过程（BRP）溶液中以提取磷脂。 组织采购解决方案减少存储组织的生物负载，并通过最小化组织肿胀来保持组织结构。 组织采购解决方案进一步减少来自进入的水和/或组织的钙，并且抑制消化胶原蛋白基质的酶。 将组织连续浸入新鲜的生物负载溶液中确保磷脂的最佳提取，从而减轻随后的组织钙化。
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