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公开(公告)号：US06322806B1
公开(公告)日：2001-11-27
申请号：US09618808
申请日：2000-07-18
IPC分类号： A61K968
CPC分类号： A23G4/20 , A23G3/343 , A23G4/08 , A23G2200/04 , A61K9/0058 , A61K9/2086 , A61K9/209
摘要： Methods and products for delivering a medicament or agent to an individual are provided as well as methods for producing the product. The product includes a coating having a medicament or agent. The medicament or agent is present within the coating that surrounds a tableted gum center (the water soluble portion and a water insoluble base portion). By chewing the gum, the medicament or agent is released from the product. Continuing to chew the chewing gum creates a pressure within the buccal cavity forcing the agent or medicament directly into the systemic system of the individual through the oral mucosa contained in the buccal cavity. This greatly enhances the absorption of the drug into the systemic system as well as the bioavailability of the drug within the system.
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公开(公告)号：US06290985B1
公开(公告)日：2001-09-18
申请号：US09759838
申请日：2001-01-11
IPC分类号： A61K928
摘要： Methods and products for delivering a medicament or agent to an individual are provided as well as methods for producing the product. The product includes a coating having a medicament or agent. The medicament or agent is present within the coating that surrounds a tableted gum center (the water soluble portion and a water insoluble base portion). By chewing the gum, the medicament or agent is released from the product. Continuing to chew the chewing gum creates a pressure within the buccal cavity forcing the agent or medicament directly into the systemic system of the individual through the oral mucosa contained in the buccal cavity. This greatly enhances the absorption of the drug into the systemic system as well as the bioavailability of the drug within the system.
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公开(公告)号：US06849280B2
公开(公告)日：2005-02-01
申请号：US10065097
申请日：2002-09-17
摘要： Gums and methods of producing gums are provided. The present invention includes a gum that has a coating layer composed of a bulk sweetener which has been formed by heating and/or searing the gum. The bulk sweetener on the surface of the gum becomes caramelized and subsequently cooled over time at desirable temperatures. The resultant coating layer includes a hardened and caramelized bulk sweetener that can enhance the flavor, the appearance, the mouthfeel and the overall recreational enjoyment of the gum during use.
摘要翻译： 提供牙龈和生产牙龈的方法。 本发明包括具有由通过加热和/或灼烧牙龈形成的增量甜味剂组成的涂层的胶。 在口香糖表面上的增量甜味剂变焦焦化，随后随时间在所需温度下冷却。 所得到的涂层包括硬化和焦糖化的散装甜味剂，其可以在使用期间增强口香糖的味道，外观，口感和整体的消费享受。
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公开(公告)号：US06558722B2
公开(公告)日：2003-05-06
申请号：US09908422
申请日：2001-07-18
IPC分类号： A23B108
CPC分类号： A23G4/025 , A23G3/0095 , A23G3/343 , A23G2220/00 , A23G2220/20
摘要： A coating process for coating a plurality of centers comprising the steps of: (a) tumbling a plurality of centers in a rotating pan; (b) wetting said plurality of centers with a grossing syrup; (c) distributing said grossing syrup amongst individual centers by rotating said pan for a period of time after wetting; (d) applying a dry charge comprising a gum base and a powdered bulk sweetener on said plurality of centers to absorb said grossing syrup, thereby forming a plurality of powder-coated centers; (e) repeating steps (b) through (d) a predetermined number of times to obtain a plurality of grossed centers; and (f) drying said plurality of grossed centers.
摘要翻译： 一种用于涂覆多个中心的涂覆方法，包括以下步骤：（a）在旋转盘中翻转多个中心; （b）用大量糖浆润湿所述多个中心; （c）通过在润湿后旋转所述盘一段时间来在各个中心之间分配所述粗浆; （d）在所述多个中心上施加包含胶基和粉末状增甜剂的干电荷以吸收所述粗糖浆，由此形成多个粉末涂覆的中心; （e）重复步骤（b）至（d）预定次数以获得多个中心; 和（f）干燥所述多个总体中心。
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公开(公告)号：US20130337107A1
公开(公告)日：2013-12-19
申请号：US14002800
申请日：2012-03-02
申请人： John Hammond , David G. Barkalow , Gwendolyn Graff , Joseph Bell , Chia-Hua Hsu
发明人： John Hammond , David G. Barkalow , Gwendolyn Graff , Joseph Bell , Chia-Hua Hsu
IPC分类号： A23G4/10
摘要： A chewing gum composition containing at least 25 wt. % water-soluble portion containing a least one simple sugar and at least one water-soluble fiber; and at least 25 wt. % water-insoluble portion containing at least 10 wt. % chewing gum base filler and at least 10 wt. % chewing gum non-filler base composition. Such a combination of water-soluble and water-insoluble materials produces a healthy amount of fiber, while creating a chewing gum with an acceptable mass duration, elasticity, cohesion, flavor delivery, and sweetness delivery.
摘要翻译： 一种口香糖组合物，其含有至少25wt。 含有至少一种单糖和至少一种水溶性纤维的％水溶性部分; 和至少25wt。 ％水不溶性部分含有至少10wt。 口香糖基础填充剂和至少10重量％ 口香糖非填料基础组成。 这种水溶性和水不溶性材料的组合产生健康量的纤维，同时产生具有可接受的质量持续时间，弹性，内聚力，风味递送和甜味递送的口香糖。
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