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公开(公告)号:US09078375B1
公开(公告)日:2015-07-07
申请号:US13532261
申请日:2012-06-25
申请人: Roy Michael Bannon , Scott McCauley
发明人: Roy Michael Bannon , Scott McCauley
CPC分类号: H05K7/20 , H05K7/20727
摘要: A hardware plane providing improved cooling air flow is disclosed herein. The hardware plane includes one or more minor planes extending from a major plane so that a gap or opening is formed for air flow. A cooling unit moves air through the gap and across the surface of hardware cards connected to the hardware plane in order to cool the hardware plane and the hardware cards. The hardware plane allows for both improved cooling air flow and for space-efficient and cost-efficient positioning of hardware cards, data buses, and control buses.
摘要翻译: 本文公开了提供改善的冷却空气流的硬件平面。 硬件平面包括从主平面延伸的一个或多个副平面,从而形成用于气流的间隙或开口。 冷却单元通过间隙移动空气并穿过连接到硬件平面的硬件卡的表面,以便冷却硬件平面和硬件卡。 硬件平面允许改进的冷却空气流量以及用于空间高效且成本有效地定位硬件卡,数据总线和控制总线的功能。
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公开(公告)号:US08512990B2
公开(公告)日:2013-08-20
申请号:US12860625
申请日:2010-08-20
申请人: Scott McCauley , Victoria Smith
发明人: Scott McCauley , Victoria Smith
IPC分类号: C12N9/02
CPC分类号: C12N9/0022 , C12Y104/03013
摘要: Disclosed herein are amino acid sequences, and encoding nucleotide sequences, of isolated catalytic domains of the LOX and LOXL2 proteins from human and mouse. Methods for the preparation and use of these isolated catalytic domains are also provided.
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公开(公告)号:US20120135004A1
公开(公告)日:2012-05-31
申请号:US13219523
申请日:2011-08-26
申请人: Scott McCauley , Maria Vaysberg
发明人: Scott McCauley , Maria Vaysberg
IPC分类号: A61K39/395 , C12N15/13 , C12N15/63 , C12N5/10 , A61P35/00 , C12N1/21 , C12N1/19 , C07K16/40 , G01N33/573
CPC分类号: C07K16/40 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要: The present disclosure provides compositions and methods of use involving binding proteins, e.g., antibodies and antigen-binding fragments thereof, that bind to the matrix metalloproteinase-9 (MMP9) protein (MMP9 is also known as gelatinase-B), wherein the binding proteins comprise an immunoglobulin (Ig) heavy chain (or functional fragment thereof) and an Ig light chain (or functional fragment thereof).
摘要翻译: 本公开提供了涉及结合基质金属蛋白酶-9(MMP9)蛋白(MMP9也称为明胶酶-B))的结合蛋白质(例如抗体及其抗原结合片段)的组合物和使用方法,其中结合蛋白 包含免疫球蛋白(Ig)重链(或其功能片段)和Ig轻链(或其功能片段)。
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公开(公告)号:US08377443B2
公开(公告)日:2013-02-19
申请号:US13219523
申请日:2011-08-26
申请人: Scott McCauley , Maria Vaysberg
发明人: Scott McCauley , Maria Vaysberg
IPC分类号: C07K16/18 , A61K39/395
CPC分类号: C07K16/40 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要: The present disclosure provides compositions and methods of use involving binding proteins, e.g., antibodies and antigen-binding fragments thereof, that bind to the matrix metalloproteinase-9 (MMP9) protein (MMP9 is also known as gelatinase-B), wherein the binding proteins comprise an immunoglobulin (Ig) heavy chain (or functional fragment thereof) and an Ig light chain (or functional fragment thereof).
摘要翻译: 本公开提供了涉及结合基质金属蛋白酶-9(MMP9)蛋白(MMP9也称为明胶酶-B))的结合蛋白质(例如抗体及其抗原结合片段)的组合物和使用方法,其中结合蛋白 包含免疫球蛋白(Ig)重链(或其功能片段)和Ig轻链(或其功能片段)。
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公开(公告)号:US20110076739A1
公开(公告)日:2011-03-31
申请号:US12860625
申请日:2010-08-20
申请人: Scott McCauley , Victoria Smith
发明人: Scott McCauley , Victoria Smith
CPC分类号: C12N9/0022 , C12Y104/03013
摘要: Disclosed herein are amino acid sequences, and encoding nucleotide sequences, of isolated catalytic domains of the LOX and LOXL2 proteins from human and mouse. Methods for the preparation and use of these isolated catalytic domains are also provided.
摘要翻译: 本文公开了来自人和小鼠的LOX和LOXL2蛋白的分离的催化结构域的氨基酸序列,并编码核苷酸序列。 还提供了制备和使用这些分离的催化结构域的方法。
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公开(公告)号:US09550836B2
公开(公告)日:2017-01-24
申请号:US14382301
申请日:2012-02-29
申请人: Victoria Smith , Scott McCauley
发明人: Victoria Smith , Scott McCauley
IPC分类号: G01N33/53 , C07K16/40 , C12N9/64 , G01N33/573 , A61K39/00
CPC分类号: C07K16/40 , A61K2039/505 , A61K2039/54 , A61K2039/545 , C07K2317/24 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C12N9/6491 , C12Y304/24035 , G01N33/573 , G01N2333/96494
摘要: The present disclosure provides compositions and methods of use involving binding proteins, e.g., antibodies and antigen-binding fragments thereof, that bind to the matrix metalloproteinase-9 (MMP9) protein (MMP9 is also known as gelatinase-B), such as where the binding proteins comprise an immunoglobulin (Ig) heavy chain (or functional fragment thereof) and an Ig light chain (or functional fragment thereof).
摘要翻译: 本公开提供涉及结合基质金属蛋白酶-9(MMP9)蛋白(MMP9也称为明胶酶-B))的结合蛋白质(例如抗体及其抗原结合片段)的组合物和使用方法,例如其中 结合蛋白质包含免疫球蛋白(Ig)重链(或其功能片段)和Ig轻链(或其功能片段)。
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公开(公告)号:US20150140580A1
公开(公告)日:2015-05-21
申请号:US14382301
申请日:2012-02-29
申请人: Victoria Smith , Scott McCauley
发明人: Victoria Smith , Scott McCauley
IPC分类号: C07K16/40 , G01N33/573
CPC分类号: C07K16/40 , A61K2039/505 , A61K2039/54 , A61K2039/545 , C07K2317/24 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C12N9/6491 , C12Y304/24035 , G01N33/573 , G01N2333/96494
摘要: The present disclosure provides compositions and methods of use involving binding proteins, e.g., antibodies and antigen-binding fragments thereof, that bind to the matrix metalloproteinase-9 (MMP9) protein (MMP9 is also known as gelatinase-B), such as where the binding proteins comprise an immunoglobulin (Ig) heavy chain (or functional fragment thereof) and an Ig light chain (or functional fragment thereof).
摘要翻译: 本公开提供涉及结合基质金属蛋白酶-9(MMP9)蛋白(MMP9也称为明胶酶-B))的结合蛋白质(例如抗体及其抗原结合片段)的组合物和使用方法,例如其中 结合蛋白质包含免疫球蛋白(Ig)重链(或其功能片段)和Ig轻链(或其功能片段)。
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公开(公告)号:US08501916B2
公开(公告)日:2013-08-06
申请号:US13619318
申请日:2012-09-14
申请人: Scott McCauley , Maria Vaysberg
发明人: Scott McCauley , Maria Vaysberg
IPC分类号: C07K16/40
CPC分类号: C07K16/40 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要: The present disclosure provides compositions and methods of use involving binding proteins, e.g., antibodies and antigen-binding fragments thereof, that bind to the matrix metalloproteinase-9 (MMP9) protein (MMP9 is also known as gelatinase-B), wherein the binding proteins comprise an immunoglobulin (Ig) heavy chain (or functional fragment thereof) and an Ig light chain (or functional fragment thereof).
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