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1.发明申请Methods and Compositions for Delivery of Catecholic Butanes for Treatment of Tumors 审中-公开用于递送用于治疗肿瘤的儿茶酚丁烷的方法和组合物公开(公告)号：US20110135711A1
公开(公告)日：2011-06-09
申请号：US12790894
申请日：2010-05-31
申请人： Ru Chih C. Huang , Richard Park , Chih-Chuan Chang , Yu-Chuan Liang , David Mold , Elaine Lin , Jonathan Heller , Neil Frazer
发明人： Ru Chih C. Huang , Richard Park , Chih-Chuan Chang , Yu-Chuan Liang , David Mold , Elaine Lin , Jonathan Heller , Neil Frazer
IPC分类号： A61K31/225 , A61K31/05 , A61K9/127 , A61K31/09 , A61K31/222 , A61P35/00 , A61P29/00 , A61P31/18
CPC分类号： A61K9/5153 , A61K9/0019 , A61K9/0024 , A61K9/0043 , A61K9/0078 , A61K9/1075 , A61K9/1271 , A61K31/205 , A61K31/24
摘要： The present invention provides kits, methods and compositions for the treatment of diseases such as cancers. The compositions herein contain a substantially pure preparation of at least one catecholic butane, including, for example, NDGA compounds in a pharmaceutically acceptable carrier or excipient. The catecholic butane such as NDGA or its derivatives are administered to one or more subjects in need of treatment by a route other than direct injection into the affected tissues or topical application on affected tissues.
摘要翻译： 本发明提供用于治疗诸如癌症的疾病的试剂盒，方法和组合物。 本文的组合物含有至少一种儿茶酚丁烷的基本上纯的制剂，包括例如药学上可接受的载体或赋形剂中的NDGA化合物。 将诸如NDGA或其衍生物的儿茶酚丁烷通过除了直接注射到受影响组织内的途径或受影响组织上的局部施用而施用于需要治疗的一个或多个受试者。
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公开(公告)号：US07728036B2
公开(公告)日：2010-06-01
申请号：US11284111
申请日：2005-11-21
申请人： Ru Chih C. Huang , Richard Park , Chih-Chuan Chang , Yu-Chuan Liang , David Mold , Elaine Lin , Jonathan Heller , Neil Frazer
发明人： Ru Chih C. Huang , Richard Park , Chih-Chuan Chang , Yu-Chuan Liang , David Mold , Elaine Lin , Jonathan Heller , Neil Frazer
IPC分类号： A61K31/22
CPC分类号： A61K9/5153 , A61K9/0019 , A61K9/0024 , A61K9/0043 , A61K9/0078 , A61K9/1075 , A61K9/1271 , A61K31/205 , A61K31/24
摘要： The present invention provides kits, methods and compositions for the treatment of tumor and other proliferative diseases such as tumors. The compositions herein contain a substantially pure preparation of at least one catecholic butane, including, for example, NDGA compounds in a pharmaceutically acceptable carrier or excipient. The catecholic butane such as NDGA or its derivatives are administered to one or more subjects in need of treatment by a route other than direct injection into the affected tissues or topical application on affected tissues.
摘要翻译： 本发明提供用于治疗肿瘤和其它增殖性疾病如肿瘤的试剂盒，方法和组合物。 本文的组合物包含至少一种儿茶酚丁烷的基本上纯的制剂，包括例如药学上可接受的载体或赋形剂中的NDGA化合物。 将诸如NDGA或其衍生物的儿茶酚丁烷通过除了直接注射到受影响组织内的途径或受影响组织上的局部施用而施用于需要治疗的一个或多个受试者。
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3.发明申请Methods and compositions for delivery of catecholic butanes for treatment of tumors 失效用于递送儿茶酚丁烷用于治疗肿瘤的方法和组合物公开(公告)号：US20060141025A1
公开(公告)日：2006-06-29
申请号：US11284111
申请日：2005-11-21
申请人： Ru Huang , Richard Park , Chih-Chuan Chang , Yu-Chuan Liang , David Mold , Elaine Lin , Jonathan Heller , Neil Frazer
发明人： Ru Huang , Richard Park , Chih-Chuan Chang , Yu-Chuan Liang , David Mold , Elaine Lin , Jonathan Heller , Neil Frazer
IPC分类号： A61K9/48 , A61K31/24 , A61K31/205
CPC分类号： A61K9/5153 , A61K9/0019 , A61K9/0024 , A61K9/0043 , A61K9/0078 , A61K9/1075 , A61K9/1271 , A61K31/205 , A61K31/24
摘要： The present invention provides kits, methods and compositions for the treatment of tumor and other proliferative diseases such as tumors. The compositions herein contain a substantially pure preparation of at least one catecholic butane, including, for example, NDGA compounds in a pharmaceutically acceptable carrier or excipient. The catecholic butane such as NDGA or its derivatives are administered to one or more subjects in need of treatment by a route other than direct injection into the affected tissues or topical application on affected tissues.
摘要翻译： 本发明提供用于治疗肿瘤和其它增殖性疾病如肿瘤的试剂盒，方法和组合物。 本文的组合物含有至少一种儿茶酚丁烷的基本上纯的制剂，包括例如药学上可接受的载体或赋形剂中的NDGA化合物。 将诸如NDGA或其衍生物的儿茶酚丁烷通过除了直接注射到受影响组织内的途径或受影响组织上的局部施用而施用于需要治疗的一个或多个受试者。
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公开(公告)号：US08440648B2
公开(公告)日：2013-05-14
申请号：US11572349
申请日：2005-07-19
申请人： Neil Frazer , Jonathan Heller , Rocio Lopez , Melissa Rhodes , Ru Chih C. Huang , Richard Dalby , Niharika Khanna
发明人： Neil Frazer , Jonathan Heller , Rocio Lopez , Melissa Rhodes , Ru Chih C. Huang , Richard Dalby , Niharika Khanna
IPC分类号： A01N37/12 , A01N37/44 , A01N27/00 , A01N43/00 , A61K31/195 , A61K31/015 , A61K31/33
CPC分类号： A61K31/015 , A61K31/195
摘要： The present invention provides for compositions, kits and methods for treatment of intraepithelial neoplasia, where the compositions include catecholic butanes, which include NDGA derivatives.
摘要翻译： 本发明提供了用于治疗上皮内瘤变的组合物，试剂盒和方法，其中组合物包括儿茶酚丁烷，其包括NDGA衍生物。
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5.发明申请Methods and compositions for delivery of catecholic butanes for treatment of obesity 审中-公开用于递送儿茶酚丁烷用于治疗肥胖症的方法和组合物公开(公告)号：US20060141047A1
公开(公告)日：2006-06-29
申请号：US11284280
申请日：2005-11-21
申请人： Jonathan Heller , Neil Frazier , Chih-Chuan Chang , Elaine Lin , Ru Huang
发明人： Jonathan Heller , Neil Frazier , Chih-Chuan Chang , Elaine Lin , Ru Huang
IPC分类号： A61K9/14
CPC分类号： A61K31/05 , A61K9/0019 , A61K9/0024 , A61K9/0043 , A61K9/0078 , A61K9/008 , A61K9/1075 , A61K9/1271 , A61K9/1272 , A61K9/146 , A61K9/204 , A61K9/5153 , A61K31/09 , Y02A50/467
摘要： The present invention provides kits, methods and compositions for the treatment of obesity. The compositions herein contain a substantially pure preparation of at least one catecholic butane, including, for example, NDGA compounds in a pharmaceutically acceptable carrier or excipient. The catecholic butane such as NDGA or its derivatives are administered to one or more subjects in need of treatment.
摘要翻译： 本发明提供用于治疗肥胖症的试剂盒，方法和组合物。 本文的组合物含有至少一种儿茶酚丁烷的基本上纯的制剂，包括例如药学上可接受的载体或赋形剂中的NDGA化合物。 将儿茶酚丁烷如NDGA或其衍生物施用于需要治疗的一个或多个受试者。
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公开(公告)号：US20080004346A1
公开(公告)日：2008-01-03
申请号：US11572349
申请日：2005-07-19
申请人： Neil Frazer , Jonathan Heller , Rocio Lopez , Melissa Rhodes , Ru Chih Huang , Richard Dalby , Niharika Khanna
发明人： Neil Frazer , Jonathan Heller , Rocio Lopez , Melissa Rhodes , Ru Chih Huang , Richard Dalby , Niharika Khanna
IPC分类号： A61K31/015 , A61K31/195 , A61P43/00
CPC分类号： A61K31/015 , A61K31/195
摘要： The present invention provides for compositions, kits and methods for treatment of intraepithelial neoplasia, where the compositions include catecholic butanes, which include NDGA derivatives.
摘要翻译： 本发明提供了用于治疗上皮内瘤变的组合物，试剂盒和方法，其中组合物包括儿茶酚丁烷，其包括NDGA衍生物。
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7.发明申请Methods and compositions for delivery of catecholic butanes for treatment of diseases 审中-公开用于递送儿茶酚丁烷用于治疗疾病的方法和组合物公开(公告)号：US20060141029A1
公开(公告)日：2006-06-29
申请号：US11284110
申请日：2005-11-21
申请人： Jonathan Heller , Neil Frazer , Amy Tsui Collins
发明人： Jonathan Heller , Neil Frazer , Amy Tsui Collins
CPC分类号： A61K9/5146 , A61K9/0019 , A61K9/0024 , A61K9/0043 , A61K9/127 , A61K9/5153 , A61K31/24 , Y02A50/467
摘要： The present invention provides kits, methods and compositions for the treatment of diseases, such as, for example, non-cancer proliferative diseases, neurodegenerative diseases, diabetes and hypertension. The compositions herein contain a substantially pure preparation of at least one catecholic butane, including, for example, NDGA Compounds in a pharmaceutically acceptable carrier or excipient by various routes of administration.
摘要翻译： 本发明提供用于治疗诸如非癌症增殖性疾病，神经变性疾病，糖尿病和高血压的疾病的试剂盒，方法和组合物。 本文的组合物含有至少一种儿茶酚丁烷的基本上纯的制剂，包括例如通过各种给药途径在药学上可接受的载体或赋形剂中的NDGA化合物。
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8.发明授权公开(公告)号：US08060536B2
公开(公告)日：2011-11-15
申请号：US11959231
申请日：2007-12-18
申请人： Guy Bavly , Jonathan Heller , Ehud Waizer
发明人： Guy Bavly , Jonathan Heller , Ehud Waizer
CPC分类号： G06F17/30876 , G06F17/30557 , G06Q10/10 , G06Q30/0621
摘要： This disclosure provides various embodiments of systems, methods, and software for managing structured and unstructured data within electronic communications. In one implementation, software identifies an electronic communication associated with a user in an enterprise application; creates a link between an unstructured data element associated with the electronic communication and a structured data element associated with the enterprise application, where the link created at least partially based on one or more attributes of the electronic communication and an active process of the enterprise application; and stores the link in a link repository.
摘要翻译： 本公开提供了用于在电子通信内管理结构化和非结构化数据的系统，方法和软件的各种实施例。 在一个实现中，软件识别与企业应用中的用户相关联的电子通信; 在与电子通信相关联的非结构化数据元素与与企业应用相关联的结构化数据元素之间创建链接，其中链路至少部分地基于电子通信的一个或多个属性和企业应用的活动过程而创建; 并将链接存储在链接库中。
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9.发明申请公开(公告)号：US20090157812A1
公开(公告)日：2009-06-18
申请号：US11959231
申请日：2007-12-18
申请人： Guy Bavly , Jonathan Heller , Ehud Waizer
发明人： Guy Bavly , Jonathan Heller , Ehud Waizer
CPC分类号： G06F17/30876 , G06F17/30557 , G06Q10/10 , G06Q30/0621
摘要： This disclosure provides various embodiments of systems, methods, and software for managing structured and unstructured data within electronic communications. In one implementation, software identifies an electronic communication associated with a user in an enterprise application; creates a link between an unstructured data element associated with the electronic communication and a structured data element associated with the enterprise application, where the link created at least partially based on one or more attributes of the electronic communication and an active process of the enterprise application; and stores the link in a link repository.
摘要翻译： 本公开提供了用于在电子通信内管理结构化和非结构化数据的系统，方法和软件的各种实施例。 在一个实现中，软件识别与企业应用中的用户相关联的电子通信; 在与电子通信相关联的非结构化数据元素与与企业应用相关联的结构化数据元素之间创建链接，其中链路至少部分地基于电子通信的一个或多个属性和企业应用的活动过程而创建; 并将链接存储在链接库中。
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公开(公告)号：US20050267208A1
公开(公告)日：2005-12-01
申请号：US11121093
申请日：2005-05-04
申请人： Ru Chih Huang , Jonathan Heller , Jih Hwu , Ko King
发明人： Ru Chih Huang , Jonathan Heller , Jih Hwu , Ko King
IPC分类号： A61K47/20 , A61K31/05 , A61K31/09 , A61K31/198 , A61K31/22 , A61K31/223 , A61K31/225 , A61K31/401 , A61K31/405 , A61K31/417 , A61P35/00 , A61P35/04 , A61P43/00 , C07C229/12
CPC分类号： A61K31/198 , A61K9/0014 , A61K9/0019 , A61K31/05 , A61K31/22 , A61K31/225 , A61K31/401 , A61K31/405 , A61K31/417
摘要： Nordihydroguaiaretic acid derivatives and methods of use thereof for the treatment of tumors.
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