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    Chromatographic column seal
    7.
    发明申请
    Chromatographic column seal 有权

    公开(公告)号：US20060027502A1

    公开(公告)日：2006-02-09

    申请号：US11247025

    申请日：2005-10-11

    申请人： Melvyn Gill ,  Neil Frazer ,  John Dunkley ,  Geoff Purdom

    发明人： Melvyn Gill ,  Neil Frazer ,  John Dunkley ,  Geoff Purdom

    IPC分类号： B01D15/08

    CPC分类号： G01N30/6026 ,  B01D15/22 ,  G01N30/6004 ,  G01N30/6017 ,  G01N2030/522

    摘要： A seal on a movable top or bottom plate for use in a chromatography column. The plate is formed of a flow distributor connected to one or more movement rods that control the movement of the top plate within a chromatography column. The plate is formed of two pieces, a flow distributor and a seal plate. The seal plate is mounted on top of the flow distributor and has a seal that is essentially co-terminal with the outer edge of the flow distributor. The seal plate is attached to the flow distributor by one or more pins or threaded bolts and forms a space between them. The one or more pins contain one or more compression means for biasing the seal plate against the flow distributor. An opening is formed in the seal plate for the selective introduction of a pressurized energy source such as compressed air, gas or hydraulic fluid into the space to overcome the compression means. One or more seals are arranged between the seal plate and distributor to maintain the pressurized energy source between the two of them. Optionally the space may contain a closed bladder or reservoir connected to the opening to contain the pressurized energy source.

    METHODS OF TREATING INFLUENZA VIRAL INFECTIONS
    8.
    发明申请
    METHODS OF TREATING INFLUENZA VIRAL INFECTIONS 审中-公开
    治疗流感病毒感染的方法

    公开(公告)号：US20090155349A1

    公开(公告)日：2009-06-18

    申请号：US12280463

    申请日：2007-02-23

    申请人： Jonathan Daniel Heller ,  Scott Matthew Laster ,  Rocio Alejandra Lopez ,  Neil Frazer

    发明人： Jonathan Daniel Heller ,  Scott Matthew Laster ,  Rocio Alejandra Lopez ,  Neil Frazer

    IPC分类号： A61K9/127 ,  A61K31/05 ,  A61K31/136 ,  A61K31/225 ,  A61K31/24 ,  A61K31/195 ,  A61K31/351 ,  A61K31/405 ,  C12N5/08 ,  C12N7/06 ,  A61K9/14 ,  A61P31/16

    CPC分类号： A61K31/085

    摘要： Methods are described for treating an influenza viral infection or associated diseases, disorders or mechanisms in a subject, comprising administering to the subject a therapeutically effective amount of a catecholic butane of the general formula (I) or a pharmaceutically acceptable salt thereof: wherein R1 and R2 each independently represents a hydrogen, a lower alkyl, a lower acyl, an alkylene, or —OR1 and —OR2 each independently represents an unsubstituted or substituted amino acid residue or pharmaceutically acceptable salt thereof; R3, R4, R5, R6, R10, R11, R12 and R13 each independently represents a hydrogen, or a lower alkyl; and R7, R8 and R9 each independently represents a hydrogen, —OH, a lower alkoxy, a lower acyloxy, an unsubstituted or substituted amino acid residue or pharmaceutically acceptable salt thereof, or any two adjacent groups together may be an alkyene dioxy; with the proviso in certain circumstances that where one of R7, R8 and R9 represents a hydrogen, then —OR1, —OR2 and the other two of R7, R8 and R9 do not simultaneously represent —OH.

    摘要翻译： 描述了用于治疗受试者中的流感病毒感染或相关疾病，病症或机制的方法，包括向受试者施用治疗有效量的通式（I）的儿茶酚丁烷或其药学上可接受的盐：其中R1和 R2各自独立地表示氢，低级烷基，低级酰基，亚烷基或-OR1和-OR2各自独立地表示未取代或取代的氨基酸残基或其药学上可接受的盐; R3，R4，R5，R6，R10，R11，R12和R13各自独立地表示氢或低级烷基; 并且R 7，R 8和R 9各自独立地表示氢，-OH，低级烷氧基，低级酰氧基，未取代或取代的氨基酸残基或其药学上可接受的盐，或任何两个相邻的基团可以是二烷氧基; 条件是在某些情况下，当R 7，R 8和R 9中的一个表示氢时，则-OR 1，-OR 2和R 7，R 8和R 9中的另外两个不同时表示-OH。

    Modular Drug Releasing System
    10.
    发明申请
    Modular Drug Releasing System 审中-公开
    模块化药物释放系统

    公开(公告)号：US20070078410A1

    公开(公告)日：2007-04-05

    申请号：US11539875

    申请日：2006-10-10

    申请人： James Chiavetta ,  William Morgan ,  Jack Tipsword ,  Neil Frazer

    发明人： James Chiavetta ,  William Morgan ,  Jack Tipsword ,  Neil Frazer

    IPC分类号： A61M5/178 ,  B65G1/00

    CPC分类号： G07F11/002 ,  A61J1/03 ,  A61J7/0084 ,  A61J7/0481 ,  G06F19/3462 ,  G07F11/46 ,  G07F11/52 ,  G07F17/0092

    摘要： Disclosed are systems and methods for processing the releasing and/or dispensing of releasable items, particularly pills, capsules, tablets, medications, and drugs. In one embodiment, a system for processing the releasing and/or dispensing releasable items includes a releasing unit configured to verify whether a cartridge is authorized for usage with a releasing unit. The releasing unit is further configured to send data corresponding to the releasable items and the activities of the items via a network and/or telephone line. The system further includes a central-computing device configured to receive the data via the network and/or telephone line and provide a database of the data to a provider, e.g., pharmacist. In one embodiment, a method for processing the releasing and/or dispensing of releasable items includes verifying whether a cartridge is authorized for usage with a releasing unit, gathering data corresponding to the releasable items from the cartridge, determining whether to release the releasable items to a user in accordance to the gathered data, recording data corresponding to the activities of the medication in a memory in the releasing unit, sending the data from the releasing unit to a central-computing device via a network and/or telephone line, wherein the central-computing device provides a database of the activities data and sends database information to a provider.

    摘要翻译： 公开了用于处理释放和/或分配可释放物品，特别是丸剂，胶囊，片剂，药物和药物的系统和方法。 在一个实施例中，用于处理释放和/或分发可释放物品的系统包括释放单元，其被配置为验证墨盒是否被授权与释放单元一起使用。 释放单元还被配置为经由网络和/或电话线路发送对应于可释放项目的数据和项目的活动。 该系统还包括配置成经由网络和/或电话线接收数据的中央计算设备，并将数据的数据提供给提供商，例如药剂师。 在一个实施例中，一种用于处理释放物品的释放和/或分发的方法包括：验证药筒是否被授权与释放单元一起使用，从盒中收集与可释放物品相对应的数据，确定是否将可释放物品释放到 用户根据所收集的数据，将与药物的活动相对应的数据记录在释放单元的存储器中，经由网络和/或电话线将数据从释放单元发送到中央计算设备，其中， 中央计算设备提供活动数据的数据库，并向提供者发送数据库信息。