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    Vascular and bodily duct treatment devices and methods
    1.
    发明授权
    Vascular and bodily duct treatment devices and methods 有权
    血管和体管治疗装置及方法

    公开(公告)号：US08795345B2

    公开(公告)日：2014-08-05

    申请号：US12573676

    申请日：2009-10-05

    申请人： Ryan M. Grandfield ,  Scott D. Wilson ,  John H. Miller ,  Emily Vu ,  Kirk L. Pedersen ,  Craig L. Bonsignore ,  Elliot H. Sanders

    发明人： Ryan M. Grandfield ,  Scott D. Wilson ,  John H. Miller ,  Emily Vu ,  Kirk L. Pedersen ,  Craig L. Bonsignore ,  Elliot H. Sanders

    IPC分类号： A61F2/06 ,  A61M29/00

    CPC分类号： A61F2/90 ,  A61F2/91 ,  A61F2230/0008

    摘要： A device including a self-expandable member having a proximal end portion, a main body portion and a distal end portion. Each of the self-expandable portions consists of a plurality of cell structures formed by intersecting strut members. In one implementation, at least one proximal cell structure in the proximal end portion has one or more struts that have a width and/or thickness greater than the width and/or thickness of the majority of strut members in the main body and distal end portions of the expandable member. Attached to at least one of the proximal-most cell structures in the proximal end portion is a proximally extending flexible wire having sufficient length and flexibility to navigate the tortuous vasculature of a patient. In another implementation, the device is delivered to the treatment site through the lumen of a delivery catheter.

    摘要翻译： 一种装置，包括具有近端部分，主体部分和远端部分的自扩张部件。 每个自展开部分由通过相交的支柱构件形成的多个单元结构组成。 在一个实施方案中，近端部分中的至少一个近端细胞结构具有一个或多个支柱，其具有大于主体中的大多数支柱构件的宽度和/或厚度的宽度和/或厚度，并且远端部分 的可扩张构件。 近端部分中的至少一个最近端的细胞结构附着有近端延伸的柔性丝，其具有足够的长度和柔性以导航患者的弯曲脉管系统。 在另一个实施方案中，该装置通过输送导管的内腔被输送到治疗部位。

    Embolic obstruction retrieval devices and methods
    2.
    发明授权
    Embolic obstruction retrieval devices and methods 有权
    栓塞梗阻检索装置及方法

    公开(公告)号：US08795317B2

    公开(公告)日：2014-08-05

    申请号：US12499713

    申请日：2009-07-08

    申请人： Ryan M. Grandfield ,  Scott D. Wilson ,  John H. Miller ,  Emily Vu ,  Kirk L. Pedersen ,  Craig L. Bonsignore ,  Elliot H. Sanders

    发明人： Ryan M. Grandfield ,  Scott D. Wilson ,  John H. Miller ,  Emily Vu ,  Kirk L. Pedersen ,  Craig L. Bonsignore ,  Elliot H. Sanders

    IPC分类号： A61F2/01 ,  A61B17/22

    CPC分类号： A61B17/221 ,  A61B2017/00867 ,  A61B2017/2215 ,  A61B2017/2217

    摘要： An embolic obstruction retrieval device including a self-expandable member having a proximal end portion, a main body portion and a distal end portion. Each of the self-expandable portions consists of a plurality of cell structures formed by intersecting strut members. At least one proximal cell structure in the proximal end portion has one or more struts that have a width and/or thickness greater than the width and/or thickness of the majority of strut members in the main body and distal end portions of the expandable member. Attached to at least one of the proximal-most cell structures in the proximal end portion is a proximally extending flexible wire having sufficient length and flexibility to navigate the tortuous vasculature and access the embolic obstruction. In one implementation, the embolic obstruction retrieval device is delivered to the embolic obstruction through the lumen of a delivery catheter.

    摘要翻译： 一种栓塞性梗塞取出装置，其包括具有近端部分，主体部分和远端部分的自扩张部件。 每个自展开部分由通过相交的支柱构件形成的多个单元结构组成。 近端部分中的至少一个近端细胞结构具有一个或多个支柱，该支柱的宽度和/或厚度大于主体中的大多数支柱构件的宽度和/或厚度以及可扩张构件的远端部分 。 附近到近端部分中的最近端的细胞结构中的至少一个是具有足够的长度和灵活性的近端延伸的柔性线，用于导航曲折的脉管系统并且进入栓塞阻塞。 在一个实施方案中，栓塞阻塞物检索装置通过输送导管的内腔被输送到栓塞阻塞物。

    VASCULAR AND BODILY DUCT TREATMENT DEVICES AND METHODS
    3.
    发明申请
    VASCULAR AND BODILY DUCT TREATMENT DEVICES AND METHODS 有权
    血管和体液治疗装置及方法

    公开(公告)号：US20110009940A1

    公开(公告)日：2011-01-13

    申请号：US12573676

    申请日：2009-10-05

    申请人： Ryan M. Grandfield ,  Scott D. Wilson ,  John H. Miller ,  Emily Vu ,  Kirk L. Pedersen ,  Craig L. Bonsignore ,  Elliot H. Sanders

    发明人： Ryan M. Grandfield ,  Scott D. Wilson ,  John H. Miller ,  Emily Vu ,  Kirk L. Pedersen ,  Craig L. Bonsignore ,  Elliot H. Sanders

    IPC分类号： A61F2/06

    CPC分类号： A61F2/90 ,  A61F2/91 ,  A61F2230/0008

    摘要： A device including a self-expandable member having a proximal end portion, a main body portion and a distal end portion. Each of the self-expandable portions consists of a plurality of cell structures formed by intersecting strut members. In one implementation, at least one proximal cell structure in the proximal end portion has one or more struts that have a width and/or thickness greater than the width and/or thickness of the majority of strut members in the main body and distal end portions of the expandable member. Attached to at least one of the proximal-most cell structures in the proximal end portion is a proximally extending flexible wire having sufficient length and flexibility to navigate the tortuous vasculature of a patient. In another implementation, the device is delivered to the treatment site through the lumen of a delivery catheter.

    摘要翻译： 一种装置，包括具有近端部分，主体部分和远端部分的自扩张部件。 每个自展开部分由通过相交的支柱构件形成的多个单元结构组成。 在一个实施方案中，近端部分中的至少一个近端细胞结构具有一个或多个支柱，其具有大于主体中的大多数支柱构件的宽度和/或厚度的宽度和/或厚度，并且远端部分 的可扩张构件。 近端部分中的至少一个最近端的细胞结构附着有近端延伸的柔性丝，其具有足够的长度和柔性以导航患者的弯曲脉管系统。 在另一实施方案中，该装置通过输送导管的内腔被输送到治疗部位。

    VASCULAR AND BODILY DUCT TREATMENT DEVICES AND METHODS
    4.
    发明申请
    VASCULAR AND BODILY DUCT TREATMENT DEVICES AND METHODS 有权
    血管和体液治疗装置及方法

    公开(公告)号：US20110184456A1

    公开(公告)日：2011-07-28

    申请号：US13021364

    申请日：2011-02-04

    申请人： Ryan M. Grandfield ,  Scott D. Wilson ,  John H. Miller ,  Elliot H. Sanders

    发明人： Ryan M. Grandfield ,  Scott D. Wilson ,  John H. Miller ,  Elliot H. Sanders

    IPC分类号： A61F2/01

    CPC分类号： A61B17/320725 ,  A61B17/32075 ,  A61B2017/22045 ,  A61B2017/320064 ,  A61B2017/320716 ,  A61F2/013 ,  A61F2/88 ,  A61F2/95 ,  A61F2002/91558 ,  A61F2250/0059

    摘要： Devices including a self-expandable member having a proximal end portion and a main body portion. The self-expandable member is movable from a first delivery position to a second placement position, in the first delivery position the expandable member being in an unexpanded position and having a nominal first diameter and in the second position the expandable member being in a radially expanded position and having a second nominal diameter greater than the first nominal diameter for deployment within a vessel or duct of a patient. The expandable member includes a plurality of cell structures with the cell structures in the main body portion extending circumferentially around a longitudinal axis of the expandable member and the cell structures in the proximal end portion extending less than circumferentially around the longitudinal axis of the expandable member to form first and second peripheral rails that vary in width along their lengths.

    摘要翻译： 包括具有近端部分和主体部分的自扩张部件的装置。 自膨胀构件可从第一输送位置移动到第二放置位置，在第一输送位置，可膨胀构件处于未膨胀位置并具有标称第一直径，并且在第二位置，可膨胀构件处于径向扩张 并且具有大于第一公称直径的第二公称直径以用于部署在患者的血管或管道内。 可扩张构件包括多个单元结构，其中主体部分中的单元结构围绕可扩展构件的纵向轴线周向延伸，并且近端部分中的单元结构沿着可扩展构件的纵向轴线的周向延伸至 形成沿其长度宽度变化的第一和第二周边轨道。

    VASCULAR AND BODILY DUCT TREATMENT DEVICES AND METHODS
    5.
    发明申请
    VASCULAR AND BODILY DUCT TREATMENT DEVICES AND METHODS 有权
    血管和体液治疗装置及方法

    公开(公告)号：US20110009950A1

    公开(公告)日：2011-01-13

    申请号：US12832857

    申请日：2010-07-08

    申请人： Ryan M. Grandfield ,  Scott D. Wilson ,  John H. Miller ,  Emily Vu ,  Kirk L. Pedersen ,  Craig L. Bonsignore ,  Elliot H. Sanders

    发明人： Ryan M. Grandfield ,  Scott D. Wilson ,  John H. Miller ,  Emily Vu ,  Kirk L. Pedersen ,  Craig L. Bonsignore ,  Elliot H. Sanders

    IPC分类号： A61F2/88 ,  A61F2/82

    CPC分类号： A61F2/91 ,  A61B17/320725 ,  A61B17/32075 ,  A61B2017/22045 ,  A61B2017/320716 ,  A61F2/88 ,  A61F2/915 ,  A61F2/95 ,  A61F2002/91558 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2230/0008 ,  A61F2250/0059

    摘要： A device including a self-expandable member having a proximal end portion and a main body portion. The self-expandable member is movable from a first delivery position to a second placement position, in the first delivery position the expandable member being in an unexpanded position and having a nominal first diameter and in the second position the expandable member being in a radially expanded position and having a second nominal diameter greater than the first nominal diameter for deployment within a vessel or duct of a patient. The expandable member includes a plurality of cell structures with the cell structures in the main body portion extending circumferentially around a longitudinal axis of the expandable member and the cell structures in the proximal end portion extending less than circumferentially around the longitudinal axis of the expandable member. In one implementation the cell structures have dimensional and material characteristics that result in about a −1.5N to a about a −3.5N overall reduction in radial force along the length of the expandable member per millimeter of expansion during about an initial 0.50 mm diametric range of expansion from the nominal diameter and that results in about a −0.10N to about a −0.50N overall reduction in radial force along the length of the expandable member per millimeter of expansion during subsequent diametric ranges of expansion.

    摘要翻译： 一种装置，包括具有近端部分和主体部分的自扩张部件。 自膨胀构件可从第一输送位置移动到第二放置位置，在第一输送位置，可膨胀构件处于未膨胀位置并具有标称第一直径，并且在第二位置，可膨胀构件处于径向扩张 并且具有大于第一公称直径的第二公称直径以用于部署在患者的血管或管道内。 可扩张构件包括多个单元结构，其中主体部分中的单元结构围绕可扩展构件的纵向轴线周向延伸，并且近端部分中的单元结构沿着可扩展构件的纵向轴线周向延伸。 在一个实施方案中，电池结构具有尺寸和材料特性，其在大约初始的0.50mm直径范围内导致沿着可膨胀元件的长度的每毫米膨胀的约-1.5N至约-3.5N的总体减小的径向力 从公称直径膨胀，并且在随后的膨胀范围内，每毫米膨胀的沿着可膨胀构件的长度的整体减小约-0.10N至约-0.50N。

    VASCULAR AND BODILY DUCT TREATMENT DEVICES AND METHODS
    6.
    发明申请
    VASCULAR AND BODILY DUCT TREATMENT DEVICES AND METHODS 审中-公开
    血管和体液治疗装置及方法

    公开(公告)号：US20110009941A1

    公开(公告)日：2011-01-13

    申请号：US12643942

    申请日：2009-12-21

    申请人： Ryan M. Grandfield ,  Scott D. Wilson ,  John H. Miller ,  Emily Vu ,  Kirk L. Pedersen ,  Craig L. Bonsignore ,  Elliot H. Sanders

    发明人： Ryan M. Grandfield ,  Scott D. Wilson ,  John H. Miller ,  Emily Vu ,  Kirk L. Pedersen ,  Craig L. Bonsignore ,  Elliot H. Sanders

    IPC分类号： A61F2/84 ,  A61F2/82

    CPC分类号： A61F2/915 ,  A61F2/01 ,  A61F2/013 ,  A61F2/88 ,  A61F2/91 ,  A61F2/95 ,  A61F2002/018 ,  A61F2002/825 ,  A61F2002/9528 ,  A61F2002/9534 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2230/0008 ,  A61F2250/0039

    摘要： A device including a self-expandable member having a proximal end portion and a main body portion. Each of the self-expandable portions consists of a plurality of cell structures formed by intersecting strut members. In one implementation, at least one proximal cell structure in the proximal end portion has one or more struts that have a width and/or thickness greater than the width and/or thickness of the majority of strut members in the main body of the expandable member. In another implementation at least some of the intersecting strut members have a thickness to width ratio of greater than one. Attached to at least one of the proximal-most cell structures in the proximal end portion is a proximally extending flexible wire having sufficient length and flexibility to navigate the tortuous vasculature of a patient. In another implementation, the device is delivered to the treatment site through the lumen of a delivery catheter.

    摘要翻译： 一种装置，包括具有近端部分和主体部分的自扩张部件。 每个自展开部分由通过相交的支柱构件形成的多个单元结构组成。 在一个实施方案中，近端部分中的至少一个近端细胞结构具有一个或多个支柱，其具有大于可扩张构件主体中大部分支柱构件的宽度和/或厚度的宽度和/或厚度 。 在另一实施方式中，至少一些交叉支柱构件的厚度与宽度之比大于1。 近端部分中的至少一个最近端的细胞结构附着有近端延伸的柔性丝，其具有足够的长度和柔性以导航患者的弯曲脉管系统。 在另一个实施方案中，该装置通过输送导管的内腔被输送到治疗部位。

    EMBOLIC OBSTRUCTION RETRIEVAL DEVICES AND METHODS
    7.
    发明申请
    EMBOLIC OBSTRUCTION RETRIEVAL DEVICES AND METHODS 有权
    EMBOLIC OBECT检索设备和方法

    公开(公告)号：US20110009875A1

    公开(公告)日：2011-01-13

    申请号：US12499713

    申请日：2009-07-08

    申请人： Ryan M. Grandfield ,  Scott D. Wilson ,  John H. Miller ,  Emily Vu ,  Kirk L. Pedersen ,  Craig L. Bonsignore ,  Elliot H. Sanders

    发明人： Ryan M. Grandfield ,  Scott D. Wilson ,  John H. Miller ,  Emily Vu ,  Kirk L. Pedersen ,  Craig L. Bonsignore ,  Elliot H. Sanders

    IPC分类号： A61B17/22

    CPC分类号： A61B17/221 ,  A61B2017/00867 ,  A61B2017/2215 ,  A61B2017/2217

    摘要： An embolic obstruction retrieval device including a self-expandable member having a proximal end portion, a main body portion and a distal end portion. Each of the self-expandable portions consists of a plurality of cell structures formed by intersecting strut members. At least one proximal cell structure in the proximal end portion has one or more struts that have a width and/or thickness greater than the width and/or thickness of the majority of strut members in the main body and distal end portions of the expandable member. Attached to at least one of the proximal-most cell structures in the proximal end portion is a proximally extending flexible wire having sufficient length and flexibility to navigate the tortuous vasculature and access the embolic obstruction. In one implementation, the embolic obstruction retrieval device is delivered to the embolic obstruction through the lumen of a delivery catheter.

    摘要翻译： 一种栓塞性梗塞取出装置，其包括具有近端部分，主体部分和远端部分的自扩张部件。 每个自展开部分由通过相交的支柱构件形成的多个单元结构组成。 近端部分中的至少一个近端细胞结构具有一个或多个支柱，其具有大于主体中的大多数支柱构件的宽度和/或厚度的宽度和/或厚度，以及可扩张构件的远端部分 。 附近到近端部分中的最近端的细胞结构中的至少一个是具有足够的长度和灵活性的近端延伸的柔性线，用于导航曲折的脉管系统并且进入栓塞阻塞。 在一个实施方案中，栓塞阻塞物检索装置通过输送导管的内腔被输送到栓塞阻塞物。

    Vascular and bodily duct treatment devices and methods
    8.
    发明授权
    Vascular and bodily duct treatment devices and methods 有权
    血管和体管治疗装置及方法

    公开(公告)号：US08357179B2

    公开(公告)日：2013-01-22

    申请号：US13021364

    申请日：2011-02-04

    申请人： Ryan M. Grandfield ,  Scott D. Wilson ,  John H. Miller ,  Elliot H. Sanders

    发明人： Ryan M. Grandfield ,  Scott D. Wilson ,  John H. Miller ,  Elliot H. Sanders

    IPC分类号： A61B17/22

    CPC分类号： A61B17/320725 ,  A61B17/32075 ,  A61B2017/22045 ,  A61B2017/320064 ,  A61B2017/320716 ,  A61F2/013 ,  A61F2/88 ,  A61F2/95 ,  A61F2002/91558 ,  A61F2250/0059

    摘要： Devices including a self-expandable member having a proximal end portion and a main body portion. The self-expandable member is movable from a first delivery position to a second placement position, in the first delivery position the expandable member being in an unexpanded position and having a nominal first diameter and in the second position the expandable member being in a radially expanded position and having a second nominal diameter greater than the first nominal diameter for deployment within a vessel or duct of a patient. The expandable member includes a plurality of cell structures with the cell structures in the main body portion extending circumferentially around a longitudinal axis of the expandable member and the cell structures in the proximal end portion extending less than circumferentially around the longitudinal axis of the expandable member to form first and second peripheral rails that vary in width along their lengths.

    摘要翻译： 包括具有近端部分和主体部分的自扩张部件的装置。 自膨胀构件可从第一输送位置移动到第二放置位置，在第一输送位置，可膨胀构件处于未膨胀位置并具有标称第一直径，并且在第二位置，可膨胀构件处于径向扩张 并且具有大于第一公称直径的第二公称直径以用于部署在患者的血管或管道内。 可扩张构件包括多个单元结构，其中主体部分中的单元结构围绕可扩展构件的纵向轴线周向延伸，并且近端部分中的单元结构沿着可扩展构件的纵向轴线周向延伸， 形成沿其长度宽度变化的第一和第二周边轨道。

    Vascular and bodily duct treatment devices and methods
    10.
    发明授权
    Vascular and bodily duct treatment devices and methods 有权
    血管和体管治疗装置及方法

    公开(公告)号：US09072537B2

    公开(公告)日：2015-07-07

    申请号：US13365884

    申请日：2012-02-03

    申请人： Ryan M. Grandfield ,  Scott D. Wilson ,  Elliot H. Sanders

    发明人： Ryan M. Grandfield ,  Scott D. Wilson ,  Elliot H. Sanders

    IPC分类号： A61F2/01 ,  A61B17/221 ,  A61B17/3207 ,  A61B17/00 ,  A61B17/22 ,  A61F2/915 ,  A61F2/82

    CPC分类号： A61B17/221 ,  A61B17/3207 ,  A61B17/320725 ,  A61B17/32075 ,  A61B2017/00778 ,  A61B2017/22045 ,  A61B2017/2215 ,  A61F2/01 ,  A61F2/915 ,  A61F2002/016 ,  A61F2002/018 ,  A61F2002/825 ,  A61F2230/0006 ,  A61F2230/0069 ,  A61F2230/0097

    摘要： Devices including, but not limited to, a self-expandable member having a proximal end portion and a main body portion. The self-expandable member is movable from a first delivery position to a second placement position, in the first delivery position the expandable member being in an unexpanded position and having a nominal first diameter and in the second position the expandable member being in a radially expanded position and having a second nominal diameter greater than the first nominal diameter for deployment within a vessel or duct of a patient. The expandable member includes a plurality of cell structures with the cell structures in the main body portion extending circumferentially around a longitudinal axis of the expandable member and the cell structures in the proximal end portion extending less than circumferentially around the longitudinal axis of the expandable member.

    摘要翻译： 包括但不限于具有近端部分和主体部分的自扩张部件的装置。 自膨胀构件可从第一输送位置移动到第二放置位置，在第一输送位置，可膨胀构件处于未膨胀位置并具有标称第一直径，并且在第二位置，可膨胀构件处于径向扩张 并且具有大于第一公称直径的第二公称直径以用于部署在患者的血管或管道内。 可扩张构件包括多个单元结构，其中主体部分中的单元结构围绕可扩展构件的纵向轴线周向延伸，并且近端部分中的单元结构沿着可扩展构件的纵向轴线周向延伸。