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公开(公告)号：US07854720B2
公开(公告)日：2010-12-21
申请号：US12624061
申请日：2009-11-23
IPC分类号： A61M5/30
CPC分类号： A61M5/30 , A61M5/2053 , A61M5/24 , A61M2005/2407 , A61M2005/2488 , A61M2005/287 , A61M2005/3104
摘要： A needle-free injection device in which a gas cartridge or other source of pressurized gas is used to advance a piston and forcibly expel injectable fluid out through an injection orifice. When a gas cartridge is used, the gas cartridge may be moveable from an initial position to an actuating position in which gas is released to drive the injection, and a recoil inhibitor may be employed to prevent the gas cartridge from moving back to the initial position. A gas cartridge seal may be disposed on the gas cartridge and moveable with the gas cartridge to seal the gas cartridge against an interior wall of a gas cartridge housing. The needle-free injection device may also be configured so that sealing is compromised upon full advancement of the piston, so as to de-pressurize the device after delivery of an injection.
摘要翻译： 无针注射装置，其中使用气瓶或其他加压气体源来推进活塞并强制地通过注射口排出可注射流体。 当使用气体盒时，气体盒可以从初始位置移动到释放气体的致动位置以驱动注射，并且可以采用反冲抑制剂以防止气体盒回到初始位置 。 气瓶密封件可以设置在气体盒上并且可与气体盒一起移动，以将气体盒密封在气体盒壳体的内壁上。 无针注射装置也可以被配置为使得在活塞完全前进时密封受到影响，以便在输送注射之后对装置进行减压。
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公开(公告)号：US07942845B2
公开(公告)日：2011-05-17
申请号：US11765245
申请日：2007-06-19
IPC分类号： A61M5/30
CPC分类号： A61M5/30 , A61M5/204 , A61M5/2053 , A61M5/31546 , A61M5/31548 , A61M5/31576
摘要： Needle-free injection devices having a drive assembly to provide an operative force to effect an injection and a dosing assembly to prepare the device for a subsequent injection. In some embodiments, the dosing assembly is configured to transfer injectate from an injectate source to the injectate assembly. In some embodiments, a portion of energy available to the drive assembly urges the injectate towards the injectate assembly. In some embodiments, the device includes a nozzle assembly having one or more ports.
摘要翻译： 无针注射装置具有驱动组件以提供操作力以实现注射和计量组合以制备用于随后注射的装置。 在一些实施例中，配量组件被配置为将注入物从注射源转移到注射组件。 在一些实施例中，可用于驱动组件的一部分能量将注射器推向注射组件。 在一些实施例中，该装置包括具有一个或多个端口的喷嘴组件。
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公开(公告)号：US07717874B2
公开(公告)日：2010-05-18
申请号：US10857591
申请日：2004-05-28
申请人： Sergio Landau , Ryan R. Beylund , James M. Bonicatto , Keith K. Daellenbach , Robert A. Miller , Theodore Walaka Sedler , John L. Staylor
发明人： Sergio Landau , Ryan R. Beylund , James M. Bonicatto , Keith K. Daellenbach , Robert A. Miller , Theodore Walaka Sedler , John L. Staylor
IPC分类号： A61M5/30
CPC分类号： A61M5/30 , A61M5/2053 , A61M5/24 , A61M2005/2407 , A61M2005/2488 , A61M2005/287 , A61M2005/3104
摘要： A needle-free injection device in which a gas cartridge or other source of pressurized gas is used to advance a piston and forcibly expel injectable fluid out through an injection orifice. When a gas cartridge is used, the gas cartridge may be moveable from an initial position to an actuating position in which gas is released to drive the injection, and a recoil inhibiter may be employed to prevent the gas cartridge from moving back to the initial position. A gas cartridge seal may be disposed on the gas cartridge and moveable with the gas cartridge to seal the gas cartridge against an interior wall of a gas cartridge housing. The needle-free injection device may also be configured so that sealing is compromised upon full advancement of the piston, so as to de-pressurize the device after delivery of an injection.
摘要翻译： 无针注射装置，其中使用气瓶或其他加压气体源来推进活塞并强制地通过注射口排出可注射流体。 当使用气体盒时，气体盒可以从初始位置移动到释放气体的致动位置以驱动喷射，并且可以采用反冲抑制器来防止气体盒回到初始位置 。 气瓶密封件可以设置在气体盒上并且可与气体盒一起移动，以将气体盒密封在气体盒壳体的内壁上。 无针注射装置也可以被配置为使得在活塞完全前进时密封受到影响，以便在输送注射之后对装置进行减压。
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公开(公告)号：US20100069831A1
公开(公告)日：2010-03-18
申请号：US12624061
申请日：2009-11-23
IPC分类号： A61M5/30
CPC分类号： A61M5/30 , A61M5/2053 , A61M5/24 , A61M2005/2407 , A61M2005/2488 , A61M2005/287 , A61M2005/3104
摘要： A needle-free injection device in which a gas cartridge or other source of pressurized gas is used to advance a piston and forcibly expel injectable fluid out through an injection orifice. When a gas cartridge is used, the gas cartridge may be moveable from an initial position to an actuating position in which gas is released to drive the injection, and a recoil inhibitor may be employed to prevent the gas cartridge from moving back to the initial position. A gas cartridge seal may be disposed on the gas cartridge and moveable with the gas cartridge to seal the gas cartridge against an interior wall of a gas cartridge housing. The needle-free injection device may also be configured so that sealing is compromised upon full advancement of the piston, so as to de-pressurize the device after delivery of an injection.
摘要翻译： 无针注射装置，其中使用气瓶或其他加压气体源来推进活塞并强制地通过注射口排出可注射流体。 当使用气体盒时，气体盒可以从初始位置移动到释放气体的致动位置以驱动注射，并且可以采用反冲抑制剂以防止气体盒回到初始位置 。 气瓶密封件可以设置在气体盒上并且可与气体盒一起移动，以将气体盒密封在气体盒壳体的内壁上。 无针注射装置也可以被配置为使得在活塞完全前进时密封受到影响，以便在输送注射之后对装置进行减压。
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公开(公告)号：US20080071211A1
公开(公告)日：2008-03-20
申请号：US11765245
申请日：2007-06-19
CPC分类号： A61M5/30 , A61M5/204 , A61M5/2053 , A61M5/31546 , A61M5/31548 , A61M5/31576
摘要： Needle-free injection devices having a drive assembly to provide an operative force to effect an injection and a dosing assembly to prepare the device for a subsequent injection. In some embodiments, the dosing assembly is configured to transfer injectate from an injectate source to the injectate assembly. In some embodiments, a portion of energy available to the drive assembly urges the injectate towards the injectate assembly. In some embodiments, the device includes a nozzle assembly having one or more ports.
摘要翻译： 无针注射装置具有驱动组件以提供操作力以实现注射和计量组合以制备用于随后注射的装置。 在一些实施例中，配量组件被配置为将注入物从注射源转移到注射组件。 在一些实施例中，可用于驱动组件的一部分能量将注射器推向注射组件。 在一些实施例中，该装置包括具有一个或多个端口的喷嘴组件。
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公开(公告)号：US07547293B2
公开(公告)日：2009-06-16
申请号：US11539585
申请日：2006-10-06
IPC分类号： A61M5/30
CPC分类号： A61M5/30 , A61M5/2053 , A61M5/50 , A61M2005/3123
摘要： Needle-free hypodermic jet injection devices having an actuation system to effect an injection from a drug delivery system. The actuation system includes an injection force assembly adapted to transmit a driving force to the drug delivery system. The actuation system further includes a trigger assembly adapted to alter the actuation system between a plurality of configurations including a fired configuration in which the injection force assembly transmits a driving force to the drug delivery system. In some embodiments, the device has a recoil restriction system including a restriction member adapted to couple the recoil restriction system to the trigger assembly and a recoil member coupled to the injection force assembly and movable relative to the restriction member. The restriction member limits movement of the recoil member once the recoil member moves a predetermined distance relative to the restriction member.
摘要翻译： 无针式皮下注射装置具有致动系统以实现药物递送系统的注射。 致动系统包括适于将驱动力传递到药物输送系统的注射力组件。 所述致动系统还包括触发器组件，其适于在多个配置之间改变所述致动系统，所述多个配置包括所述喷射构造，其中所述喷射力组件将驱动力传递到所述药物输送系统。 在一些实施例中，该装置具有反冲限制系统，其包括适于将反冲限制系统耦合到触发器组件的限制构件和联接到喷射力组件并可相对于限制构件移动的反冲构件。 一旦反冲构件相对于限制构件移动预定距离，限制构件限制反冲构件的运动。
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公开(公告)号：US08105272B2
公开(公告)日：2012-01-31
申请号：US12480561
申请日：2009-06-08
IPC分类号： A61M5/30
CPC分类号： A61M5/30 , A61M5/2053 , A61M5/50 , A61M2005/3123
摘要： Needle-free hypodermic jet injection devices having an actuation system to effect an injection from a drug delivery system. The actuation system includes an injection force assembly adapted to transmit a driving force to the drug delivery system. The actuation system further includes a trigger assembly adapted to alter the actuation system between a plurality of configurations including a fired configuration in which the injection force assembly transmits a driving force to the drug delivery system. In some embodiments, the device has a recoil restriction system including a restriction member adapted to couple the recoil restriction system to the trigger assembly and a recoil member coupled to the injection force assembly and movable relative to the restriction member. The restriction member limits movement of the recoil member once the recoil member moves a predetermined distance relative to the restriction member.
摘要翻译： 无针式皮下注射装置具有致动系统以实现药物递送系统的注射。 致动系统包括适于将驱动力传递到药物输送系统的注射力组件。 所述致动系统还包括触发器组件，其适于在多个配置之间改变所述致动系统，所述多个配置包括所述喷射构造，其中所述喷射力组件将驱动力传递到所述药物输送系统。 在一些实施例中，该装置具有反冲限制系统，其包括适于将反冲限制系统耦合到触发器组件的限制构件和联接到喷射力组件并可相对于限制构件移动的反冲构件。 一旦反冲构件相对于限制构件移动预定距离，限制构件限制反冲构件的运动。
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公开(公告)号：US20090247940A1
公开(公告)日：2009-10-01
申请号：US12480561
申请日：2009-06-08
IPC分类号： A61M5/307
CPC分类号： A61M5/30 , A61M5/2053 , A61M5/50 , A61M2005/3123
摘要： Needle-free hypodermic jet injection devices having an actuation system to effect an injection from a drug delivery system. The actuation system includes an injection force assembly adapted to transmit a driving force to the drug delivery system. The actuation system further includes a trigger assembly adapted to alter the actuation system between a plurality of configurations including a fired configuration in which the injection force assembly transmits a driving force to the drug delivery system. In some embodiments, the device has a recoil restriction system including a restriction member adapted to couple the recoil restriction system to the trigger assembly and a recoil member coupled to the injection force assembly and movable relative to the restriction member. The restriction member limits movement of the recoil member once the recoil member moves a predetermined distance relative to the restriction member.
摘要翻译： 无针式皮下注射装置具有致动系统以实现药物递送系统的注射。 致动系统包括适于将驱动力传递到药物输送系统的注射力组件。 所述致动系统还包括触发器组件，其适于在多个配置之间改变所述致动系统，所述多个配置包括所述喷射构造，其中所述喷射力组件将驱动力传递到所述药物输送系统。 在一些实施例中，该装置具有反冲限制系统，其包括适于将反冲限制系统耦合到触发器组件的限制构件和联接到喷射力组件并可相对于限制构件移动的反冲构件。 一旦反冲构件相对于限制构件移动预定距离，限制构件限制反冲构件的运动。
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公开(公告)号：US20080086079A1
公开(公告)日：2008-04-10
申请号：US11539585
申请日：2006-10-06
IPC分类号： A61M5/307
CPC分类号： A61M5/30 , A61M5/2053 , A61M5/50 , A61M2005/3123
摘要： Needle-free hypodermic jet injection devices having an actuation system to effect an injection from a drug delivery system. The actuation system includes an injection force assembly adapted to transmit a driving force to the drug delivery system. The actuation system further includes a trigger assembly adapted to alter the actuation system between a plurality of configurations including a fired configuration in which the injection force assembly transmits a driving force to the drug delivery system. In some embodiments, the device has a recoil restriction system including a restriction member adapted to couple the recoil restriction system to the trigger assembly and a recoil member coupled to the injection force assembly and movable relative to the restriction member. The restriction member limits movement of the recoil member once the recoil member moves a predetermined distance relative to the restriction member.
摘要翻译： 无针式皮下注射装置具有致动系统以实现药物递送系统的注射。 致动系统包括适于将驱动力传递到药物输送系统的注射力组件。 所述致动系统还包括触发器组件，其适于在多个配置之间改变所述致动系统，所述多个配置包括所述喷射构造，其中所述喷射力组件将驱动力传递到所述药物输送系统。 在一些实施例中，该装置具有反冲限制系统，其包括适于将反冲限制系统耦合到触发器组件的限制构件和联接到喷射力组件并可相对于限制构件移动的反冲构件。 一旦反冲构件相对于限制构件移动预定距离，限制构件限制反冲构件的运动。
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