公开(公告)号：US12017047B2

公开(公告)日：2024-06-25

申请号：US17516099

申请日：2021-11-01

Applicant: kaleo, Inc.

Inventor： Paul F. Meyers ,  Michael J. Roe

IPC: A61M5/20

CPC classification number: A61M5/2053 ,  A61M5/2046 ,  A61M2205/0216 ,  A61M2205/3334

Abstract: An apparatus includes a housing, an energy storage member, a carrier, a medicament container, and a delivery control mechanism. The housing defines a gas chamber configured to receive pressurized gas from the energy storage member to pressurize the gas chamber. The carrier has a proximal surface that defines a portion of the gas chamber. The medicament container is coupled to the carrier and has a distal end portion coupled to a delivery member. The medicament container contains a medicament and includes an elastomeric member that seals the medicament within the medicament container. The delivery control mechanism is coupled to a proximal end portion of the medicament container and includes a flow restriction member for regulating a pressure supplied by the gas chamber and entering into the medicament container that acts on the elastomeric member.

公开(公告)号：US11865077B2

公开(公告)日：2024-01-09

申请号：US17056560

申请日：2019-06-26

Applicant: Ferrosan Medical Devices A/S

Inventor： Kristian Larsen ,  Peter Lund Hammershøj

IPC: A61J1/20 ,  A61M5/162 ,  A61M5/178 ,  A61M5/19 ,  A61M5/20 ,  A61M5/24 ,  A61M35/00 ,  A61B17/00 ,  A61J1/06 ,  A61M39/00

CPC classification number: A61J1/2096 ,  A61B17/00491 ,  A61J1/06 ,  A61J1/201 ,  A61J1/2017 ,  A61J1/2048 ,  A61J1/2082 ,  A61J1/2089 ,  A61M5/162 ,  A61M5/1782 ,  A61M5/19 ,  A61M5/2046 ,  A61M5/2053 ,  A61M5/2425 ,  A61M5/2448 ,  A61M35/003 ,  A61B2017/00495 ,  A61M2039/0027

Abstract: The invention regards a device for reconstituting a bioactive agent and forming a flowable paste, the device comprising: —a base configured for receiving: —a first container containing a liquid, and —a second container containing the bioactive agent, —a syringe containing a paste forming material, the syringe being attachable to the base, wherein the base has a first conduit for fluidly connecting the first container with the second container and a second conduit for fluidly connecting the second container with the syringe, and wherein the first container is configured to be pressurizable such that when the first and second containers are received at the base, the liquid is forced through the first conduit into the second container, thereby reconstituting the bioactive agent, and the reconstituted bioactive agent is forced through the second conduit into the syringe, such that a paste is formed.

公开(公告)号：US11844933B2

公开(公告)日：2023-12-19

申请号：US16933779

申请日：2020-07-20

Applicant: AKTIVAX, INC.

Inventor： Amir Genosar

IPC: A61M5/20 ,  A61M5/32 ,  A61M5/00 ,  A61M39/22 ,  A61M5/28 ,  A61M5/31

CPC classification number: A61M5/2066 ,  A61M5/008 ,  A61M5/2053 ,  A61M5/3234 ,  A61M39/22 ,  A61M5/282 ,  A61M2005/206 ,  A61M2005/2026 ,  A61M2005/3126 ,  A61M2209/088

Abstract: An auto-injector operable in a single activation step. The auto-injector is automatically armed when removed from its carrying receptacle. The auto-injector may be prefilled with more than one constituent of a beneficial agent, stored in separated compartments, in such an arrangement that the compartments will automatically merge when the auto-injector is removed from its carrying receptacle.

公开(公告)号：US11819218B2

公开(公告)日：2023-11-21

申请号：US16320591

申请日：2017-07-26

Applicant: PROVENSIS LIMITED

Inventor： Carol Suzanne Balfour ,  David Ian Faulkner ,  Stafford Moss ,  Thomas Wyss ,  Rex Faithfull ,  Thomas Ajao

IPC: A61B17/00 ,  A61B17/12 ,  A61J3/00 ,  B01F35/83 ,  B01F35/71 ,  B01F35/21 ,  B01F23/235 ,  B29C44/60 ,  A61M5/20 ,  B29C44/02 ,  B29K105/04 ,  B29L31/00

CPC classification number: A61B17/12186 ,  A61B17/0057 ,  A61B17/00491 ,  A61B17/12031 ,  A61B17/12109 ,  A61B17/12181 ,  A61J3/00 ,  B01F23/235 ,  B01F35/2111 ,  B01F35/7176 ,  B01F35/83 ,  B01F35/831 ,  B29C44/60 ,  A61B2017/00526 ,  A61B2017/00893 ,  A61M5/2053 ,  B29C44/02 ,  B29K2105/04 ,  B29L2031/7534

Abstract: The present invention relates to methods and devices for production of injectable foams, such as those used in the treatment of varicose veins and other venous disorders. The method requires the delivery or supply of foamable liquid sclerosing agent and a suitable gas or a gas mixture to a foam producing structure in which the liquid and gas are combined to produce foam, wherein the liquid is delivered independently of the delivery of gas. Devices for producing injectable foam comprise a foam producing structure in which liquid and gas are combined to produce foam, the structure comprising an inlet for liquid and gas and an outlet for foam; a liquid pathway in communication with the inlet; and a gas pathway in communication with the inlet, characterised in that the liquid pathway comprises a means for delivering liquid through the liquid pathway independently of gas delivery through the gas pathway. In preferred embodiments, the delivery of liquid and/or gas is controlled with volumetric pumps.

公开(公告)号：US20230364353A1

公开(公告)日：2023-11-16

申请号：US18044657

申请日：2021-09-01

Applicant: Eli Lilly and Company

Inventor： William Godwin ATTERBURY ,  Corrie Jo BENNISON ,  Yelena N. DAVIS ,  Jeffrey LeClair ELLIS ,  David Arthur HOLLEY ,  John Paul TALLARICO ,  Jessica Diane YOUNG

IPC: A61M5/32 ,  A61M39/26 ,  A61M5/20

CPC classification number: A61M5/3234 ,  A61M39/26 ,  A61M5/2053 ,  A61M2205/36 ,  A61M2205/50

Abstract: A therapeutic agent delivery system includes a therapeutic agent delivery assembly carried by a housing. The therapeutic agent delivery assembly includes a chamber including a first passageway, a therapeutic agent carried in the first passageway, and a needle in communication with the first passageway. The therapeutic agent delivery assembly is translatable relative to the housing from a stowed configuration to a deployed configuration. The therapeutic agent delivery assembly is also translatable relative to the housing from the deployed configuration to a retracted configuration. The system further includes a user input that is actuatable to translate the therapeutic agent delivery assembly from the stowed configuration to the deployed configuration. The system further includes a retraction mechanism that is actuatable to translate the therapeutic agent delivery assembly from the deployed configuration to the retracted configuration.

公开(公告)号：US11672911B2

公开(公告)日：2023-06-13

申请号：US16626291

申请日：2018-06-27

Applicant: DAICEL CORPORATION

Inventor： Takamasa Suzuki ,  Shingo Atobe ,  Hiroshi Miyazaki ,  Hiromitsu Iga ,  Katsuya Miki

IPC: A61M5/178 ,  A61M5/20 ,  A61M5/30

CPC classification number: A61M5/2046 ,  A61M5/2053 ,  A61M5/30 ,  A61M2205/3331 ,  A61M2205/50 ,  A61M2205/8206

Abstract: A needleless injector pressurizes a substance to be injected having an ejection pressure defined as a pressure of the substance to be injected ejected through an ejection port. The ejection pressure is raised to a first peak pressure after pressurizing is started, is lowered to a pressure lower than the first peak pressure afterward, and then is raised to a second peak pressure again. An on-completion reached depth that is an on-completion reached depth of the substance when the pressurizing portion completes pressurizing is adjustable, the on-completion reached depth being increased along with increase of the first peak pressure and being increased along with reduction of a length between peaks from a first timing at which the ejection pressure reaches the first peak pressure to a second timing at which the ejection pressure reaches the second peak pressure.

公开(公告)号：US20190183674A1

公开(公告)日：2019-06-20

申请号：US16284185

申请日：2019-02-25

Applicant: ORBIT BIOMEDICAL LIMITED

Inventor： Mark C. Tsai ,  Brian M. Gatton, JR. ,  Michael F. Keane ,  Isaac J. Khan ,  Brendan J. Oberkircher ,  Daniel W. Price

IPC: A61F9/00 ,  A61M5/315 ,  A61M5/31 ,  A61M5/20

CPC classification number: A61F9/0008 ,  A61M5/2053 ,  A61M5/3137 ,  A61M5/31501 ,  A61M5/31505 ,  A61M5/3158 ,  A61M5/31595 ,  A61M2005/2086 ,  A61M2005/31508 ,  A61M2005/3154 ,  A61M2039/1077

Abstract: A system for storing and delivering a predetermined amount of fluid includes a syringe including a barrel, a flange disposed at the proximal end of the barrel, and a plunger assembly configured to be received in the lumen of the barrel. The plunger assembly includes a piston and a plunger rod. The plunger rod is removably couplable to the piston at the distal end of the plunger rod and includes a thumb press flange at the proximal end of the plunger rod. The system further includes a stop feature that is removably couplable to the syringe or the plunger assembly. The stop feature is configured to arrest distal advancement of the plunger assembly relative to the syringe when the plunger assembly reaches a predetermined position relative to the syringe. The stop thus ensures that a predetermined amount of fluid remains in the barrel.

公开(公告)号：US10058649B2

公开(公告)日：2018-08-28

申请号：US15029437

申请日：2014-10-13

Applicant: APTAR FRANCE SAS

Inventor： François Le Maner

IPC: A61M5/00 ,  A61M5/20 ,  B05B11/00 ,  A61M11/00 ,  A61M15/08

CPC classification number: A61M5/002 ,  A61M5/2053 ,  A61M11/007 ,  A61M15/08 ,  A61M2205/276 ,  A61M2209/06 ,  B05B11/0032 ,  B05B11/3059

Abstract: A packaging device for packaging a fluid dispenser (200), said dispenser comprising at least one reservoir (210) containing fluid, and a dispenser unit (220) that is actuated manually so as to dispense said fluid, said packaging device comprising a casing (100) that is provided with a base body (110) and with a cover (120) that is separable from said base body (110), starting from a closed position in which said dispenser (200) is packaged in said casing (100) and going to an open position in which said dispenser (200) may be removed from said casing (100), said casing (100) including at least one projection (130) that is adapted to co-operate with said dispenser (200) at least in the closed position of the cover (120), so as to block said dispenser unit (220) and prevent it from being actuated.

公开(公告)号：US20180161501A1

公开(公告)日：2018-06-14

申请号：US15891459

申请日：2018-02-08

Applicant: Windgap Medical, Inc.

Inventor： Adam Standley ,  Cole Constantineau ,  Christopher Stepanian ,  Brent Buchine ,  Jeffery Thomas Chagnon

IPC: A61M5/19 ,  A61M5/20 ,  A61M5/315 ,  A61M5/28 ,  A61M39/22

CPC classification number: A61M5/19 ,  A61M5/2033 ,  A61M5/2053 ,  A61M5/2066 ,  A61M5/28 ,  A61M5/288 ,  A61M5/31596 ,  A61M5/3202 ,  A61M5/3243 ,  A61M5/3245 ,  A61M5/3271 ,  A61M39/22 ,  A61M2005/2013 ,  A61M2005/206 ,  A61M2005/3128

Abstract: Contemplated herein is a medication mixing device which can include a housing having therein a first chamber containing a first medicament component and a second chamber provided containing a second medicament component provided with a sealing structure selectively isolating the first chamber from the second chamber. The sealing structure can include a first sealing component having a first sealing interface and a second sealing component having a second sealing interface wherein a first compression force can be applied to the first and second sealing components causes the sealing interfaces to form a seal. The first compression force can then be configured to allow the first sealing component and the second sealing component to maintain at least one degree of freedom with respect to one another.

公开(公告)号：US20180154081A1

公开(公告)日：2018-06-07

申请号：US15575229

申请日：2016-06-03

Applicant: MEDIMOP Medical Projects Ltd.

Inventor： Yossi BAR-EL ,  Gil YIGAL ,  Reuven Y. FILMAN

IPC: A61M5/24

CPC classification number: A61M5/2422 ,  A61M5/14244 ,  A61M5/2033 ,  A61M5/2053 ,  A61M5/24 ,  A61M5/2466 ,  A61M2005/2414 ,  A61M2005/2437 ,  A61M2005/2477 ,  A61M2005/2496

Abstract: A method and assembly are disclosed for interfacing between a drug cartridge and a drug delivery device. Optionally, the drug delivery device includes a compartment that retains the cartridge during drug delivery and/or a stopper pushing assembly mounted to the device behind (proximal to) the compartment. In some embodiments, the cartridge may be inserted laterally into the compartment in front of the pushing assembly. For example, the delivery device may include a moving cartridge bay. The cartridge is optionally inserted into the bay and/or the bay and cartridge optionally move into the cartridge compartment. Alternatively or additionally, the cartridge compartment may have a proximal opening into which the cartridge is inserted and/or the pushing assembly may be moved into position after insertion of the cartridge. In some embodiments the cartridge may have a distal seal that is broken by a longitudinal movement.