-
公开(公告)号：US06453243B1
公开(公告)日：2002-09-17
申请号：US09884833
申请日：2001-06-18
IPC分类号： C12Q168
摘要： A method for displaying results of hybridization experiments using a biochip is provided. In the method, a plurality of control spots spotted in each of a plurality of sections defined on a biochip is measured. The measured data are plotted on a graph for each section, and all of the graphs are simultaneously displayed on a single screen in the same arrangement as that of the sections on the biochip. By simultaneously displaying all of the graphs on a single screen, it is possible to skim the whole biochip to find experimental errors. Also, experimental errors can be quantified with respect to the dispersion of control data on the basis of the linearity of the data points and slope angles defined for each data points on a graph.
-
2.发明授权公开(公告)号：US07277798B2
公开(公告)日：2007-10-02
申请号：US09739525
申请日：2000-12-14
摘要： The present invention provides methods for extracting similar expression patterns and related biopolymers considering natures that are characteristic of expression data of, for example, genes. A segment of experiment cases which includes an expression of interest is selected as a search range among an expression pattern of a reference gene or the like. By comparing the selected segment of the expression pattern with expression patterns of a group of candidate genes or the like, genes having an expression pattern with at least a partial similarity are searched from the group of candidate genes. A partially taken out curve (a part of an, expression pattern) is transferred to overlap an expression pattern curve of a candidate gene to search expression patterns with a similar pattern shape.
摘要翻译： 本发明提供了考虑到例如基因表达数据的特征的性质来提取类似表达模式和相关生物聚合物的方法。 选择包括感兴趣的表达的实验病例段作为参考基因等的表达模式之间的搜索范围。 通过将所选择的表达模式片段与一组候选基因等的表达模式进行比较，从候选基因组中搜索具有至少部分相似性的表达模式的基因。 转移部分取出的曲线（表达模式的一部分）与候选基因的表达模式曲线重叠以搜索具有相似图案形状的表达模式。
-
公开(公告)号：US07031847B1
公开(公告)日：2006-04-18
申请号：US09677042
申请日：2000-09-29
CPC分类号： G06K9/6218 , G06F19/20 , G06F19/24 , G06F19/26 , G06K2209/07
摘要： The present invention discloses a method for displaying gene expression patterns of multiple genes that change according to the experiment cases, where a first axis represents the genes and a second axis represents the experiment cases. The method comprises two steps. The first step consists of designating a segment along the second axis in the expression pattern data of the multiple genes. The second step comprises clustering the expression pattern data within the designated segment along the second axis based on a predetermined reference value, repeating clustering within the same cluster in a forward or reverse direction along the second axis while changing the reference value, and displaying the results according to a predetermined display format.
摘要翻译： 本发明公开了一种用于显示根据实验情况而变化的多个基因的基因表达模式的方法，其中第一轴代表基因，第二轴代表实验情况。 该方法包括两个步骤。 第一步包括在多个基因的表达模式数据中沿着第二个轴指定一个片段。 第二步包括基于预定参考值沿着第二轴聚集指定段内的表达模式数据，在改变参考值的同时沿着第二轴沿正向或相反方向重复在同一簇内的聚类，并显示结果 根据预定的显示格式。
-
公开(公告)号：US07315785B1
公开(公告)日：2008-01-01
申请号：US09890929
申请日：2000-11-17
IPC分类号： G06F19/00
CPC分类号： G06F19/26 , G06F19/24 , G06K9/6219 , G06K9/6254
摘要： The present invention represents a global state of branches in a whole dendrogram as well as detail of states of individual subtrees, to aid focusing of groupings and selection of a clustering method. The present invention selects a branch/subtree in a dendrogram displays the subtree on a separate window, replaces the subtree with an icon then restores the icon into the original subtree, and/or searches keywords contained in information of biopolymers in the subtree then highlight the locations of biopolymers containing the keywords in its information.
摘要翻译： 本发明表示整个树状图中的分支的全局状态以及各个子树的状态的细节，以帮助分组的聚焦和聚类方法的选择。 本发明选择树形图中的分支/子树在单独的窗口上显示子树，用图标替换子树，然后将图标恢复到原始子树中，和/或搜索包含在子树中的生物聚合物的信息中的关键字，然后突出显示 在其信息中含有关键词的生物聚合物的位置。
-
公开(公告)号：US07010430B2
公开(公告)日：2006-03-07
申请号：US09819179
申请日：2001-03-27
摘要： The present invention aims at providing a visual display which is useful in roughly understanding the state of groupings and changes, by comparing expression data of genes from two experiments based on expression data of one sample common to both experiments.In order to compare data of expression levels obtained from different experiments each using two types of samples, three types of expression levels are displayed in three-dimension as mediated by the data of the common sample used in both experiments. Specifically, expression level data for Samples A and B and expression level data for Samples A and C are combined and converted into single three-dimensional data and displayed as points inside a sphere. Alternatively, expression states of each gene to Samples A, B and C are mapped on a sphere with respect to a ratio between Sample A and Sample B and a ratio between Samples A and C, and displayed as distribution on the surface of the sphere. A clustering analysis is performed based on the distributed points inside or on the sphere, to visually understand the expression state of genes for the three types of samples. In addition, the expression level data displayed as points inside or on the sphere are linked as a line or a curve for each gene or for each gene group resulting from the clustering analysis, to visually understand the changes of expression states with time.
-
6.发明授权公开(公告)号：US07428527B2
公开(公告)日：2008-09-23
申请号：US10720178
申请日：2003-11-25
申请人： Tsunehiko Watanabe , Junji Yoshii , Tadashi Mizunuma , Yuichi Minesaki , Fumitoshi Ogura , Keisuke Yamamoto , Tateo Nagai
发明人： Tsunehiko Watanabe , Junji Yoshii , Tadashi Mizunuma , Yuichi Minesaki , Fumitoshi Ogura , Keisuke Yamamoto , Tateo Nagai
CPC分类号： G06F17/30566 , G06F19/28 , Y10S707/99933 , Y10S707/99945
摘要： Necessary information can be easily extracted from a plurality of databases 11 in which biological substance information is stored. Data is downloaded from the plurality of databases. From the downloaded data is extracted information indicating links between two databases, a detailed description of each data, and sequence data for homology search, which together constitute an index. The thus extracted index 15 is distributed to a user facility, where a user 18 conducts a search using the distributed index.
摘要翻译： 可以容易地从存储有生物物质信息的多个数据库11提取必要的信息。 从多个数据库中下载数据。 从下载的数据中提取指示两个数据库之间的链接的信息，每个数据的详细描述以及一起构成索引的同源性搜索的序列数据。 这样提取的索引15被分配给用户设备，用户18使用分布式索引进行搜索。
-
-
-
-
-
搜索结果
6 条记录 (耗时 0.019 秒)
