公开(公告)号：US20050095242A1

公开(公告)日：2005-05-05

申请号：US10505980

申请日：2003-02-28

申请人： Ryuzo Ueda ,  Shigeki Sato ,  Takeo Yoshinouchi ,  Takashi Niimi ,  Shigeki Shimizu ,  Tadaaki Eimoto

发明人： Ryuzo Ueda ,  Shigeki Sato ,  Takeo Yoshinouchi ,  Takashi Niimi ,  Shigeki Shimizu ,  Tadaaki Eimoto

IPC分类号： A61P11/00 ,  C07K16/28 ,  G01N33/50 ,  G01N33/68 ,  A61K39/395

CPC分类号： G01N33/6863 ,  C07K16/2866 ,  C07K2317/24 ,  C07K2317/565 ,  G01N33/505

摘要： A preventive agent, a diagnostic agent or a therapeutic agent for interstitial pneumonia, which comprises an anti-CCR4 antibody and/or an anti-CXCR3 antibody as an active ingredient, a diagnostic agent for discriminating between usual idiopathic interstitial pneumonia and non-specific idiopathic interstitial pneumonia which comprises an anti-CCR4 antibody and an anti-CXCR3 antibody as an active ingredient, and a method for discriminating between usual idiopathic interstitial pneumonia and non-specific idiopathic interstitial pneumonia, which comprises detecting and/or determining a Th2 cell and a Th1 cell in a sample by using an anti-CCR4 antibody and an anti-CXCR3 antibody.

摘要翻译： 作为间质性肺炎的预防剂，诊断剂或治疗剂，其包含抗CCR4抗体和/或抗CXCR3抗体作为活性成分，用于鉴别常见特发性间质性肺炎与非特异性特发性 包含抗CCR4抗体和抗CXCR3抗体作为活性成分的间质性肺炎以及通常的特发性间质性肺炎与非特异性特发性间质性肺炎的鉴别方法，其特征在于，检测和/或测定Th2细胞和 通过使用抗CCR4抗体和抗CXCR3抗体，样品中的Th1细胞。