ROTATING FRAME PULSED NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
    1.
    发明申请
    ROTATING FRAME PULSED NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY 有权
    旋转框架脉冲核磁共振光谱

    公开(公告)号:US20140232391A1

    公开(公告)日:2014-08-21

    申请号:US13768965

    申请日:2013-02-15

    CPC classification number: G01V3/32 G01N24/081 G01R33/448 G01R33/4633

    Abstract: An NMR method and apparatus for analyzing a sample of interest applies a static magnetic field together with RF pulses of oscillating magnetic field across a sample volume that encompasses the sample of interest. The RF pulses are defined by a pulse sequence that includes a plurality of measurement segments configured to characterize a plurality of relaxation parameters related to relaxation of nuclear magnetization of the sample of interest. Signals induced by the RF pulses are detected in order to derive the relaxation parameters. The measurement segments of the pulse sequence include at least one first-type measurement segment configured to characterize relaxation of spin-lattice interaction between nuclei of the sample of interest in a rotating frame (T1ρ) at a predefined frequency. The T1ρ parameter can be measured in conjunction with the measurement of other relaxation and/or diffusion parameters as part of multidimensional NMR experiments.

    Abstract translation: 用于分析感兴趣样品的NMR方法和装置将静态磁场与围绕感兴趣样品的样品体积的振荡磁场的RF脉冲一起施加。 RF脉冲由包括多个测量段的脉冲序列限定,该多个测量段被配置为表征与感兴趣样品的核磁化弛豫相关的多个弛豫参数。 检测由RF脉冲引起的信号以导出松弛参数。 脉冲序列的测量段包括至少一个第一类型测量段,其被配置为以预定频率表征旋转帧(T1&rgr)中感兴趣的样本的核之间的自旋 - 晶格相互作用的弛豫。 T1&rgr 参数可以与其他松弛和/或扩散参数的测量一起进行测量,作为多维NMR实验的一部分。

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