公开(公告)号：US20200230254A1

公开(公告)日：2020-07-23

申请号：US16319147

申请日：2017-07-21

申请人： SEATTLE GENETICS, INC.

发明人： Ana Kostic

IPC分类号： A61K47/68 ,  A61K39/395 ,  A61P35/00 ,  A61K31/573 ,  A61K31/675 ,  A61K31/475 ,  A61K31/704

摘要： This invention relates to treatment of Diffuse Large B-Cell Lymphoma (DLBCL) and Follicular Lymphoma (FL). Specifically, the disclosure provides a method of treating a subject having DLBCL or FL, the method comprising administering to the subject a drug combination consisting essentially of a CD19 antibody drug conjugate (CD19-ADC), and rituximab, cyclophosphamide, doxorubicin, and prednisone (RCHP).

公开(公告)号：US11325980B2

公开(公告)日：2022-05-10

申请号：US16085511

申请日：2017-03-15

申请人： SEATTLE GENETICS, INC.

发明人： Django Sussman ,  Fu Li ,  Ana Kostic

IPC分类号： A61K31/337 ,  A61K31/555 ,  A61K31/704 ,  C07K16/30 ,  A61K39/395 ,  A61K47/68 ,  C07K16/28 ,  A61K9/00 ,  A61K39/00

摘要： The invention provides methods of treating a subject having or at risk of cancer by administering a LIV-1 antibody drug conjugate and a chemotherapeutic.

公开(公告)号：US20190085091A1

公开(公告)日：2019-03-21

申请号：US16085511

申请日：2017-03-15

申请人： SEATTLE GENETICS, INC.

发明人： Django Sussman ,  Fu Li ,  Ana Kostic

IPC分类号： C07K16/30 ,  A61K9/00 ,  A61K31/337 ,  A61K31/555 ,  A61K31/704

摘要： The invention provides methods of treating a subject having or at risk of cancer by administering a LIV-1 antibody drug conjugate and a chemotherapeutic.