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公开(公告)号:US20190076549A1
公开(公告)日:2019-03-14
申请号:US16085460
申请日:2017-03-15
发明人: William Arthur , Robert Thurman , Travis Biechele , Rory Rohm
摘要: This invention relates to treatment of cancer using antibody drug conjugates that comprise PBD molecules in combination with Bcl-2 inhibitors.
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公开(公告)号:US20160185858A1
公开(公告)日:2016-06-30
申请号:US14948183
申请日:2015-11-20
CPC分类号: C07K16/28 , A61K47/6865 , A61K2039/505 , C07K16/3015 , C07K16/3053 , C07K16/3069 , C07K16/465 , C07K2317/24 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/732 , C07K2317/92
摘要: The invention provides humanized antibodies that specifically bind to LIV-1. The antibodies are useful for treatment and diagnoses of various cancers as well as detecting LIV-1.
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公开(公告)号:US20180079810A1
公开(公告)日:2018-03-22
申请号:US15692424
申请日:2017-08-31
CPC分类号: C07K16/28 , A61K47/6865 , A61K2039/505 , C07K16/3015 , C07K16/3053 , C07K16/3069 , C07K16/465 , C07K2317/24 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/732 , C07K2317/92
摘要: The invention provides humanized antibodies that specifically bind to LIV-1. The antibodies are useful for treatment and diagnoses of various cancers as well as detecting LIV-1.
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公开(公告)号:US09783608B2
公开(公告)日:2017-10-10
申请号:US14948183
申请日:2015-11-20
CPC分类号: C07K16/28 , A61K47/6865 , A61K2039/505 , C07K16/3015 , C07K16/3053 , C07K16/3069 , C07K16/465 , C07K2317/24 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/732 , C07K2317/92
摘要: The invention provides humanized antibodies that specifically bind to LIV-1. The antibodies are useful for treatment and diagnoses of various cancers as well as detecting LIV-1.
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公开(公告)号:US20190262354A1
公开(公告)日:2019-08-29
申请号:US16308225
申请日:2017-06-08
发明人: William Arthur , Travis Biechele , Rory Rohm , Robert Thurman
IPC分类号: A61K31/551 , C07K16/28 , A61K31/519 , A61K31/497 , A61K31/5377 , A61K31/553 , A61K31/706 , A61K47/68 , A61K9/00
摘要: This invention relates to treatment of cancer using a antibody drug conjugates that comprise PBD molecules in combination with FLT3 inhibitors.
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6.
公开(公告)号:US20130259860A1
公开(公告)日:2013-10-03
申请号:US13990778
申请日:2011-12-06
CPC分类号: C07K16/28 , A61K47/6865 , A61K2039/505 , C07K16/3015 , C07K16/3053 , C07K16/3069 , C07K16/465 , C07K2317/24 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/732 , C07K2317/92
摘要: The invention provides humanized antibodies that specifically bind to LIV-1. The antibodies are useful for treatment and diagnoses of various cancers as well as detecting LIV-1.
摘要翻译: 本发明提供特异性结合LIV-1的人源化抗体。 该抗体可用于治疗和诊断各种癌症以及检测LIV-1。
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