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1.
公开(公告)号:US20200255444A1
公开(公告)日:2020-08-13
申请号:US16755551
申请日:2018-10-12
发明人: Yang ZHANG , Wentao WU , Guangwen YANG , Zhixiang LI , Jikui SUN , Jie LI , Jian LI , Shuhui CHEN
IPC分类号: C07D493/10 , A61P23/00
摘要: The present invention relates to a series of 2,6-dioxaspiro [4,5] decane derivatives and applications thereof in preparation of opiate receptor p agonist related drugs; and in particular relates to the derivative compounds shown in formula (I), tautomers thereof or pharmaceutically acceptable compositions thereof.
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公开(公告)号:US20210403485A1
公开(公告)日:2021-12-30
申请号:US17281209
申请日:2019-09-29
发明人: Jianfei WANG , Yang ZHANG , Jikui SUN , Shuhui CHEN
IPC分类号: C07D498/22 , A61P35/00
摘要: The present invention discloses a compound of formula (II), a tautomer thereof or a pharmaceutically acceptable salt thereof, and relates to use thereof in preparing a medicament for treating solid tumor-related diseases.
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