公开(公告)号：US09643941B2

公开(公告)日：2017-05-09

申请号：US15301763

申请日：2015-03-27

Applicant: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

Inventor： Fajun Nan ,  Jia Li ,  Xin Xie ,  Chaojun Gong ,  Yubo Zhou ,  Hui Chai ,  Yangming Zhang ,  Mingbo Su

IPC: C07D277/56 ,  C07D417/04 ,  C07D417/14 ,  C07D277/66 ,  C07D277/60

CPC classification number: C07D277/56 ,  C07D277/60 ,  C07D277/66 ,  C07D417/04 ,  C07D417/14

Abstract: The present invention relates to a thiazole-based compound, a preparation method therefor, and a use thereof. More specifically, the present invention relates to a 2,2′-bis-thiazole-based compound, a preparation method therefor, and a use of 2,2′-bis-thiazole-based compound a histone deacetylase inhibitor in the preparation of an antitumor medicament, a medicament for treating autoimmune diseases, a medicament for treating type II diabetes mellitus and complication thereof, or a medicament for treating neurodegenerative diseases.