公开(公告)号：US10259798B2

公开(公告)日：2019-04-16

申请号：US15301265

申请日：2015-02-09

申请人： SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES ,  SHANGHAI GREEN VALLEY PHARMACEUTICAL CO., LTD.

发明人： Lijiang Xuan ,  Yiping Wang ,  Weibin Song ,  Chunguang Chen ,  Dingxiang Li ,  Xiaoyu Zhou ,  Yunlong Gu ,  Liang Hu ,  Jing Zhao ,  Wenwei Xu ,  Shumei Wang

IPC分类号： A61K36/00 ,  C07D307/86 ,  A61K31/343 ,  A61K36/537

摘要： The present invention relates to a method for preparing magnesium lithospermate B. The method is characterized in that: magnesium lithospermate B is extracted or purified from a Salvia miltiorrhiza plant material or a Salvia miltiorrhiza extract in the presence of an added magnesium salt. The present invention also relates to a high-purity magnesium lithospermate B product prepared by the method of the present invention, wherein the content of magnesium lithospermate B is more than 95% by weight.

公开(公告)号：US20170137399A1

公开(公告)日：2017-05-18

申请号：US15301265

申请日：2015-02-09

申请人： SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES ,  SHANGHAI GREEN VALLEY PHARMACEUTICAL CO., LTD.

发明人： Lijiang Xuan ,  Yiping Wang ,  Weibin Song ,  Chunguang Chen ,  Dingxiang Li ,  Xiaoyu Zhou ,  Yunlong Gu ,  Liang Hu ,  Jing Zhao ,  Wenwei Xu ,  Shumei Wang

IPC分类号： C07D307/86

CPC分类号： C07D307/86 ,  A61K31/343 ,  A61K36/537

摘要： The present invention relates to a method for preparing magnesium lithospermate B. The method is characterized in that: magnesium lithospermate B is extracted or purified from a Salvia miltiorrhiza plant material or a Salvia miltiorrhiza extract in the presence of an added magnesium salt. The present invention also relates to a high-purity magnesium lithospermate B product prepared by the method of the present invention, wherein the content of magnesium lithospermate B is more than 95% by weight.