SYSTEMS AND METHODS FOR ELECTRON CRYOTOMOGRAPHY RECONSTRUCTION

    公开(公告)号:US20240412377A1

    公开(公告)日:2024-12-12

    申请号:US18542803

    申请日:2023-12-18

    Abstract: Described herein are methods and non-transitory computer-readable media of a computing system configured to obtain a plurality of images of an object from a plurality of orientations at a plurality of times. A machine learning model is encoded to represent a continuous density field of the object that maps a spatial coordinate to a density value. The machine learning model comprises a deformation module configured to deform the spatial coordinate in accordance with a timestamp and a trained deformation weight. The machine learning model further comprises a neural radiance module configured to derive the density value in accordance with the deformed spatial coordinate, the timestamp, a direction, and a trained radiance weight. The machine learning model is trained using the plurality of images. A three-dimensional structure of the object is constructed based on the trained machine learning model.

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