公开(公告)号：US20240412377A1

公开(公告)日：2024-12-12

申请号：US18542803

申请日：2023-12-18

Applicant: SHANGHAITECH UNIVERSITY

Inventor： Peihao WANG ,  Jiakai ZHANG ,  Xinhang LIU ,  Zhijie LIU ,  Jingyi YU

IPC: G06T7/149 ,  G06T9/00 ,  G06T15/10

Abstract: Described herein are methods and non-transitory computer-readable media of a computing system configured to obtain a plurality of images of an object from a plurality of orientations at a plurality of times. A machine learning model is encoded to represent a continuous density field of the object that maps a spatial coordinate to a density value. The machine learning model comprises a deformation module configured to deform the spatial coordinate in accordance with a timestamp and a trained deformation weight. The machine learning model further comprises a neural radiance module configured to derive the density value in accordance with the deformed spatial coordinate, the timestamp, a direction, and a trained radiance weight. The machine learning model is trained using the plurality of images. A three-dimensional structure of the object is constructed based on the trained machine learning model.

公开(公告)号：US20240161484A1

公开(公告)日：2024-05-16

申请号：US18418386

申请日：2024-01-22

Applicant: SHANGHAITECH UNIVERSITY

Inventor： Peihao WANG ,  Jiakai ZHANG ,  Xinhang LIU ,  Zhijie LIU ,  Jingyi YU

IPC: G06V10/82 ,  G06T7/37

CPC classification number: G06V10/82 ,  G06T7/37 ,  G06T2207/20084

Abstract: A computer-implemented method is provided. The method includes obtaining a plurality of images representing projections of an object placed in a plurality of poses and a plurality of translations; assigning a pose embedding vector, a flow embedding vector and a contrast transfer function (CTF) embedding vector to each image; encoding, by a computer device, a machine learning model comprising a pose network, a flow network, a density network and a CTF network; training the machine learning model using the plurality of images; and reconstructing a 3D structure of the object based on the trained machine learning module.

公开(公告)号：US20250163065A1

公开(公告)日：2025-05-22

申请号：US18840522

申请日：2023-01-06

Applicant: SHANGHAITECH UNIVERSITY

Inventor： Jianjun CHENG ,  Zhijie LIU ,  Tian HUA ,  Jianhang MAO ,  Ning ZHOU

IPC: C07D487/04 ,  A61K31/53 ,  A61K31/5377 ,  A61P25/18

Abstract: Provided are a pyrrolotriazinone compound represented by formula I or a pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising same, a preparation method therefor, and use thereof. The pyrrolotriazinone compound has agonistic activity on GPR139 receptor.