公开(公告)号：US20220401590A1

公开(公告)日：2022-12-22

申请号：US17772259

申请日：2020-11-04

申请人： SHIZUOKA PREFECTURAL UNIVERSITY CORPORATION ,  MEDICAL CORPORATION KINSHUKAI ,  HAMAMATSU PHOTONICS K.K.

发明人： Kenichiro TODOROKI ,  Yoshitaka HAMASHIMA ,  Hiromichi EGAMI ,  Satoshi NAKAGAWA ,  Toshihiro SAKAI ,  Osamu INOUE ,  Shingo NISHIYAMA ,  Masakatsu KANAZAWA ,  Hideo TSUKADA

IPC分类号： A61K51/04 ,  C07B59/00

摘要： The present invention relates to a compound represented by the following General Formula (1) or a salt thereof. In General Formula (1), R1, R2, R3 and R4 each independently represent a hydrogen atom, a linear or branched alkyl group which may have a substituent or the like. R1 and R2 may be bonded to each other to form a ring. R3 and R4 may be bonded to each other to form a ring. R1 and/or R2 may be bonded to a 6-membered ring to which —NR1R2 is bonded to form a ring. R3 and/or R4 may be bonded to a 6-membered ring to which —NR3R4 is bonded to form a ring. R5 represents —11CH3, a linear or branched alkyl group which may have a substituent or the like. R6 represents —F, —18F or the like. X, Y and Z each independently represent a carbon atom, an oxygen atom or the like. n is 0 or 1.

公开(公告)号：US20160256578A1

公开(公告)日：2016-09-08

申请号：US15029012

申请日：2014-09-18

申请人： HAMAMATSU PHOTONICS K.K.

发明人： Hideo TSUKADA ,  Masakatsu KANAZAWA ,  Norihiro HARADA ,  Shingo NISHIYAMA

IPC分类号： A61K51/04

CPC分类号： A61K51/0459

摘要： The present invention provides a diagnostic agent for a therapeutic effect on cancer, containing a compound represented by formula (1-0). (In formula (1-0), R represents —O(CH2)n—, —O(CH2)nOC2H4—, —CH2O(CH2)n—, or —CH2O(CH2)nOC2H4—, n represents an integer of 1 to 5, and Q1 represents F or —OCH3.)

摘要翻译： 本发明提供了含有式（1-0）所示化合物的癌症治疗效果的诊断剂。 （式（1-0）中，R表示-O（CH2）n-，-O（CH2）nOC2H4-，-CH2O（CH2）n-或-CH2O（CH2）nOC2H4-，n表示1 至5，且Q1表示F或-OCH 3）