专利检索 ap:("SICHUAN BAILI PHARMACEUTICAL CO., LTD") AND inv:"Tao K. XU" 第 1 页

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发明申请
CAMPTOTHECIN DERIVATIVE AND CONJUGATE THEREOF 有权

公开(公告)号：US20220411436A1

公开(公告)日：2022-12-29

申请号：US17761417

申请日：2020-09-17

申请人： SICHUAN BAILI PHARMACEUTICAL CO., LTD

发明人： Yi ZHU , Weili WAN , Shi ZHUO , Wei ZHANG , Yiying ZHANG , Tao K. XU

IPC分类号： C07D491/22 , A61P35/00 , C07K5/103 , A61K47/68

摘要： An antitumor pharmaceutical camptothecin derivative and an antibody-drug conjugate thereof. By means of a series of molecular structure modifications, an optimal camptothecin antitumor drug is obtained, so as to be more suitable as a drug for antibody conjugation.