公开(公告)号：US20210129149A1

公开(公告)日：2021-05-06

申请号：US17074689

申请日：2020-10-20

Applicant: SINGAPORE UNIVERSITY OF TECHNOLOGY AND DESIGN

Inventor： Ye Ai ,  David Collins ,  Richard O'Rorke

IPC: B01L3/00

Abstract: A microfluidic device includes a substrate and a microfluidic channel, wherein the microfluidic channel is configured to form a fluid pathway for allowing a fluid sample comprising particles to flow along the microfluidic channel; and a single transducer provided on the substrate for producing an acoustic travelling wave that propagates on the substrate surface towards an interaction region associated with the microfluidic channel as the fluid sample is flowing through the microfluidic channel. The microfluidic channel comprises three channel portions having three orientations, respectively, that are different from each other with respect to a direction of the propagation path of the travelling acoustic wave in the interaction region, the three channel portions arranged to produce fluid wavefronts based on substrate-propagated acoustic waves such that the fluid wavefronts and subsequent substrate-propagated acoustic wavefronts interfere with one another to generate periodic acoustic force fields in the fluid sample for manipulating the particles.