公开(公告)号：US11603531B1

公开(公告)日：2023-03-14

申请号：US17502824

申请日：2021-10-15

Applicant: SKYHAWK THERAPEUTICS, INC.

Inventor： Michael Luzzio ,  Kathleen McCarthy ,  William Haney

IPC: C12N15/113 ,  C07D401/14 ,  C07D403/14 ,  C07D451/02 ,  C07D451/04 ,  C07D451/14 ,  C07D471/04 ,  C07D471/08 ,  C07D487/08 ,  C07D491/08 ,  C07D471/10

Abstract: Described herein are small molecule splicing modulator compounds that modulate splicing of mRNA, such as pre-mRNA, encoded by genes, and methods of use of the small molecule splicing modulator compounds for modulating splicing and treating diseases and conditions.

公开(公告)号：US11091475B2

公开(公告)日：2021-08-17

申请号：US16818590

申请日：2020-03-13

Applicant: SKYHAWK THERAPEUTICS, INC.

Inventor： Michael Luzzio ,  Kathleen McCarthy ,  William Haney

IPC: A61K31/501 ,  C07D451/02 ,  C07D491/08 ,  C07D403/14 ,  C07D451/14 ,  C07D471/04 ,  C07D401/14 ,  C07D487/08 ,  C07D471/08 ,  C07D471/10

Abstract: Described herein are small molecule splicing modulator compounds that modulate splicing of mRNA, such as pre-mRNA, encoded by genes, and methods of use of the small molecule splicing modulator compounds for modulating splicing and treating diseases and conditions.

公开(公告)号：US11021708B2

公开(公告)日：2021-06-01

申请号：US16818599

申请日：2020-03-13

Applicant: SKYHAWK THERAPEUTICS, INC.

Inventor： Michael Luzzio ,  Kathleen McCarthy ,  William Haney

IPC: C07H21/04 ,  C12N15/113 ,  C07D401/14 ,  C07D403/14 ,  C07D451/02 ,  C07D451/14 ,  C07D471/04 ,  C07D471/08 ,  C07D471/10 ,  C07D487/08 ,  C07D491/08 ,  C07D451/04

Abstract: Described herein are small molecule splicing modulator compounds that modulate splicing of mRNA, such as pre-mRNA, encoded by genes, and methods of use of the small molecule splicing modulator compounds for modulating splicing and treating diseases and conditions.

公开(公告)号：US11162101B2

公开(公告)日：2021-11-02

申请号：US16781524

申请日：2020-02-04

Applicant: SKYHAWK THERAPEUTICS, INC.

Inventor： Michael Luzzio ,  Kathleen McCarthy ,  William Haney

IPC: C07D451/02 ,  C07D451/14 ,  C07D403/14 ,  C07D487/08 ,  C07D401/14 ,  C07D471/04 ,  C07D471/10 ,  C07D491/08 ,  C07D471/08 ,  C12N15/113 ,  C07D451/04

Abstract: Described herein are small molecule splicing modulator compounds that modulate splicing of mRNA, such as pre-mRNA, encoded by genes, and methods of use of the small molecule splicing modulator compounds for modulating splicing and treating diseases and conditions.

公开(公告)号：US11008572B2

公开(公告)日：2021-05-18

申请号：US16781803

申请日：2020-02-04

Applicant: SKYHAWK THERAPEUTICS, INC.

Inventor： Michael Luzzio ,  Kathleen McCarthy ,  William Haney

IPC: C07D451/14 ,  C07D451/04 ,  C07D403/14 ,  C12N15/113 ,  C07D401/14 ,  C07D451/02 ,  C07D471/04 ,  C07D471/08 ,  C07D471/10 ,  C07D487/08 ,  C07D491/08

Abstract: Described herein are small molecule splicing modulator compounds that modulate splicing of mRNA, such as pre-mRNA, encoded by genes, and methods of use of the small molecule splicing modulator compounds for modulating splicing and treating diseases and conditions.

公开(公告)号：US11434489B1

公开(公告)日：2022-09-06

申请号：US17502818

申请日：2021-10-15

Applicant: SKYHAWK THERAPEUTICS, INC.

Inventor： Michael Luzzio ,  Kathleen McCarthy ,  William Haney

IPC: C12N15/113 ,  C07D401/14 ,  C07D403/14 ,  C07D451/02 ,  C07D451/04 ,  C07D451/14 ,  C07D471/04 ,  C07D471/08 ,  C07D471/10 ,  C07D487/08 ,  C07D491/08

Abstract: Described herein are small molecule splicing modulator compounds that modulate splicing of mRNA, such as pre-mRNA, encoded by genes, and methods of use of the small molecule splicing modulator compounds for modulating splicing and treating diseases and conditions.

公开(公告)号：US11326165B1

公开(公告)日：2022-05-10

申请号：US17502810

申请日：2021-10-15

Applicant: SKYHAWK THERAPEUTICS, INC.

Inventor： Michael Luzzio ,  Kathleen McCarthy ,  William Haney

IPC: C12N15/113 ,  C07D401/14 ,  C07D403/14 ,  C07D451/02 ,  C07D451/04 ,  C07D451/14 ,  C07D471/04 ,  C07D471/08 ,  C07D471/10 ,  C07D487/08 ,  C07D491/08

Abstract: Described herein are small molecule splicing modulator compounds that modulate splicing of mRNA, such as pre-mRNA, encoded by genes, and methods of use of the small molecule splicing modulator compounds for modulating splicing and treating diseases and conditions.

公开(公告)号：US20200224199A1

公开(公告)日：2020-07-16

申请号：US16818599

申请日：2020-03-13

Applicant: SKYHAWK THERAPEUTICS, INC.

Inventor： Michael Luzzio ,  Kathleen Mccarthy ,  William Haney

IPC: C12N15/113

Abstract: Described herein are small molecule splicing modulator compounds that modulate splicing of mRNA, such as pre-mRNA, encoded by genes, and methods of use of the small molecule splicing modulator compounds for modulating splicing and treating diseases and conditions.