公开(公告)号：US3654080A

公开(公告)日：1972-04-04

申请号：US3654080D

申请日：1970-01-05

Applicant: STANDARD BRANDS INC

Inventor： BENGTSON BARBARA L ,  LAMM WILLIAM R

IPC: C12N9/92 ,  C12B1/00 ,  C12C11/04 ,  C12D

CPC classification number: C12N9/92 ,  Y10S435/886

Abstract: THE DISCLOSURE IS DIRECTED TO A PROCESS OF ENZYMATICALLY CONVERTING A PORTION OF THE GLUCOSE IN A GLUCOSE-CONTAINING SOLUTION TO FRUCTOSE. VIABLE MICROORGANISM WHICH CONTAIN INTRACELLULAR GLUCOSE ISOMERASE ARE TREATED WITH A TOXIC AGENT OT DESTROY AT LEAST 95 PERCENT OF THE MICROORGANISMS. THE TREATED MICROORGANISM ARE CULTURED TO PROMOTE GROWTH, AND THE CELLULAR MATERIAL THEREFROM IS INCORPORATED INTO A GLUCOSE SOLUTION WHEREIN CONDITIONS ARE MAINTAINED TO CONVERT A PORTION OF THE GLUCOSE TO FRUCTOSE.