公开(公告)号：US20130323310A1

公开(公告)日：2013-12-05

申请号：US13866764

申请日：2013-04-19

Applicant: STC.UNM

Inventor： Hugh D. Smyth ,  Martin J. Donovan

IPC: A61K9/00

CPC classification number: A61K9/0073 ,  A61K9/0075 ,  A61K9/0078 ,  A61K9/1641 ,  A61K47/60 ,  A61K47/6949 ,  A61K48/00 ,  B82Y5/00 ,  Y10T428/2982

Abstract: Swellable particles for delivering a working agent to the pulmonary system comprise a plurality of biodegradable particles each formed from a polymer network, each of the plurality of biodegradable particles having a mass mean aerodynamic diameter not exceeding 5 μm, the particles being swellable by hydration to a size that is greater than 6 μm volume mean diameter, and a working agent entrapped in the polymer network of each of the plurality of biodegradable particles.

Abstract translation: 用于将工作剂递送到肺系统的可溶胀颗粒包括多个可生物降解的颗粒，每个由聚合物网络形成，所述多个可生物降解的颗粒中的每一个具有不超过5μm的质量平均空气动力学直径，所述颗粒可以通过水合膨胀至 尺寸大于6μm体积平均直径，以及包埋在多个生物可降解颗粒中的每一个的聚合物网络中的工作剂。