公开(公告)号：US20180161398A1

公开(公告)日：2018-06-14

申请号：US15889393

申请日：2018-02-06

Applicant: STEMDR INC.

Inventor： Myung Kwan HAN ,  Chae Hwa YOO ,  Eun Kyung SONG ,  Seung Ok LEE

IPC: A61K38/21

CPC classification number: A61K38/215 ,  A61P31/04

Abstract: The present invention relates to a composition containing an inducer of SIRT1 (silent mating type information regulation 2 homolog) expression for preventing or treating sepsis or septic shock. The inducer of SIRT1 expression can remarkably reduce the mortality caused by sepsis or septic shock by reducing pro-inflammatory cytokines and increasing anti-inflammatory cytokines. Therefore, the inducer of SIRT1 expression is useful for preventing or treating sepsis or septic shock.