公开(公告)号：US20180161398A1

公开(公告)日：2018-06-14

申请号：US15889393

申请日：2018-02-06

Applicant: STEMDR INC.

Inventor： Myung Kwan HAN ,  Chae Hwa YOO ,  Eun Kyung SONG ,  Seung Ok LEE

IPC: A61K38/21

CPC classification number: A61K38/215 ,  A61P31/04

Abstract: The present invention relates to a composition containing an inducer of SIRT1 (silent mating type information regulation 2 homolog) expression for preventing or treating sepsis or septic shock. The inducer of SIRT1 expression can remarkably reduce the mortality caused by sepsis or septic shock by reducing pro-inflammatory cytokines and increasing anti-inflammatory cytokines. Therefore, the inducer of SIRT1 expression is useful for preventing or treating sepsis or septic shock.

公开(公告)号：US20230248682A1

公开(公告)日：2023-08-10

申请号：US18188537

申请日：2023-03-23

Applicant: STEMDR INC. ,  INDUSTRIAL COOPERATION FOUNDATION CHONBUK NATIONAL UNIVERSITY ,  KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY

Inventor： Myung-Kwan HAN ,  Kwangho LEE

IPC: A61K31/198 ,  A23L33/175 ,  A23L33/00 ,  A61P17/04 ,  A61K8/02 ,  A61K8/44 ,  A61K8/49 ,  A61K31/405 ,  A61Q19/00

CPC classification number: A61K31/198 ,  A23L33/175 ,  A23L33/40 ,  A61P17/04 ,  A61K8/0212 ,  A61K8/442 ,  A61K8/4913 ,  A61K31/405 ,  A61Q19/007 ,  A23V2002/00

Abstract: The present disclosure relates to a composition for preventing, alleviating or treating pruritus and/or atopy using an N-acetylamino acid or an N-acylamino acid having almost no side effects on the human body. Also, the present disclosure relates to a cosmetic composition for moisturizing skin or soothing skin. The composition of the present disclosure may be utilized to ameliorate a problematic skin condition caused by various causes, or to safely and effectively alleviate or treat pruritus and/or atopy without concern about side effects.

公开(公告)号：US20200316001A1

公开(公告)日：2020-10-08

申请号：US16766891

申请日：2018-11-23

Applicant: STEMDR INC. ,  INDUSTRIAL COOPERATION FOUNDATION CHONBUK NATIONAL UNIVERSITY ,  KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY

Inventor： Myung-Kwan HAN

IPC: A61K31/198 ,  A61K31/405 ,  A61K8/49 ,  A61K8/44 ,  A61K8/02 ,  A61P17/04 ,  A61Q19/00 ,  A23L33/175 ,  A23L33/00

Abstract: The present disclosure relates to a composition for preventing, alleviating or treating pruritus and/or atopy using an N-acetylamino acid or an N-acylamino acid having almost no side effects on the human body. Also, the present disclosure relates to a cosmetic composition for moisturizing skin or soothing skin. The composition of the present disclosure may be utilized to ameliorate a problematic skin condition caused by various causes, or to safely and effectively alleviate or treat pruritus and/or atopy without concern about side effects.

公开(公告)号：US11413333B2

公开(公告)日：2022-08-16

申请号：US15889393

申请日：2018-02-06

Applicant: STEMDR INC.

Inventor： Myung Kwan Han ,  Chae Hwa Yoo ,  Eun Kyung Song ,  Seung Ok Lee

IPC: A61K38/21 ,  A61P31/04

Abstract: The present invention relates to a composition containing an inducer of SIRT1 (silent mating type information regulation 2 homolog) expression for preventing or treating sepsis or septic shock. The inducer of SIRT1 expression can remarkably reduce the mortality caused by sepsis or septic shock by reducing pro-inflammatory cytokines and increasing anti-inflammatory cytokines. Therefore, the inducer of SIRT1 expression is useful for preventing or treating sepsis or septic shock.

公开(公告)号：US20200030283A1

公开(公告)日：2020-01-30

申请号：US16493485

申请日：2017-12-12

Applicant: INDUSTRIAL COOPERATION FOUNDATION CHONBUK NATIONAL UNIVERSITY ,  STEMDR INC.

Inventor： Myung-Kwan HAN ,  Hern-Ku LEE ,  So-Jeong KIM ,  Suhn-Young IM ,  Baik-Hwan CHO ,  Jeong-Soo PARK

IPC: A61K31/353 ,  A23L33/10 ,  A61K8/49 ,  A61Q19/00 ,  A61P17/04

Abstract: The present disclosure relates to a composition for preventing, improving or treating pruritus by using a naturally derived ingredient. The composition of the present disclosure may be used to improve or treat pruritus caused by various causes safely and effectively without the risk of side effects.

公开(公告)号：US20220233502A1

公开(公告)日：2022-07-28

申请号：US17613583

申请日：2020-05-21

Applicant: STEMDR INC.

Inventor： Myung-Kwan HAN ,  Kwangho LEE

IPC: A61K31/405 ,  A61K31/196 ,  A23L33/00 ,  A23L33/175 ,  A61P11/06 ,  A61P11/08

Abstract: The present disclosure relates to a composition for preventing, alleviating or treating asthma, rhinitis and/or conjunctivitis using an N-acylamino acid, which has almost no side effect on the human body. The composition of the present disclosure has an excellent effect of alleviating the symptoms of asthma by exhibiting alleviation effects on both inflammatory response in the airway and airway fibrosis, which are major clinical symptoms of asthma, and thus can be effectively used in drugs or foods for alleviating asthma. In addition, it can be usefully used in drugs or foods for alleviating rhinitis and conjunctivitis since it significantly alleviates the clinical symptoms of rhinitis and conjunctivitis.

公开(公告)号：US20220233485A1

公开(公告)日：2022-07-28

申请号：US17668678

申请日：2022-02-10

Applicant: STEMDR INC. ,  INDUSTRIAL COOPERATION FOUNDATION CHONBUK NATIONAL UNIVERSITY ,  KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY

Inventor： Myung-Kwan HAN ,  Kwangho LEE

IPC: A61K31/198 ,  A23L33/175 ,  A23L33/00 ,  A61P17/04 ,  A61K8/02 ,  A61K8/44 ,  A61K8/49 ,  A61K31/405 ,  A61Q19/00

Abstract: The present disclosure relates to a composition for preventing, alleviating or treating pruritus and/or atopy using an N-acetylamino acid or an N-acylamino acid having almost no side effects on the human body. Also, the present disclosure relates to a cosmetic composition for moisturizing skin or soothing skin. The composition of the present disclosure may be utilized to ameliorate a problematic skin condition caused by various causes, or to safely and effectively alleviate or treat pruritus and/or atopy without concern about side effects.

公开(公告)号：US20210308096A1

公开(公告)日：2021-10-07

申请号：US17351399

申请日：2021-06-18

Applicant: INDUSTRIAL COOPERATION FOUNDATION CHONBUK NATIONAL UNIVERSITY ,  STEMDR INC.

Inventor： Myung-Kwan HAN ,  Hern-Ku LEE ,  So-Jeong KIM ,  Suhn-Young IM ,  Baik-Hwan CHO ,  Jeong-Soo PARK

IPC: A61K31/353 ,  A23L33/10 ,  A61P17/04 ,  A61K8/49 ,  A61Q19/00

Abstract: The present disclosure relates to a composition for preventing, improving or treating pruritus by using a naturally derived ingredient. The composition of the present disclosure may be used to improve or treat pruritus caused by various causes safely and effectively without the risk of side effects.