公开(公告)号：US3398169A

公开(公告)日：1968-08-20

申请号：US47055465

申请日：1965-07-08

Applicant: STUDIENGESELLSCHAFT KOHLE MBH

Inventor： PAUL NEUMANN WILHELM ,  ALFRED PEDAIN JOSEF

IPC: C07F7/22

CPC classification number: C07F7/2232 ,  C07F7/2216

Abstract: Halogen-containing organo-tin compounds are prepared by reacting organo-tin-halohydrides with compounds having unsaturated groups (e.g. olefins, alkynes, aldehydes, ketones, unsaturated nitriles, Schiff's bases, and azo compounds) preferably in the presence of a radical producing catalyst (e.g. benzyl hyponitrile, azoisobutyric dinitrile or an azoisobutyric dialkyl ester) at less than 50 DEG C. with or without a solvent in an inert atmosphere (N2). Alkyl, aryl or aralkyl tin halohydrides of the formulae R2Sn(X)H,RSn(X)H2 or RSn(X2)H (preferably where R=C1-C8 alkyl or simple aryl, e.g. Ph) are prepared in situ from the corresponding organo-tin hydrides and organotin halides and may be reacted with the unsaturated compound to give organo-tin halohydrides with dissimilar organo-radicals and/or containing functional groups. The Sn-H group adds across the multiple bond. The following compounds are among those prepared in the examples: Ex. 2: (isoBu)2Sn(Br)-CH2-CH2CN; Ex. 3: Ph2Sn(Cl)-CH2-CHMePh; Ex. 5: Ph2Sn(Cl)(CH2)6-Sn(Cl)Ph2; Ex. 6: (nBu)2Sn(Cl)(CH2)3O(CH2)2OH; Ex. 11: EtSn(Br)2CH=CHPh; Ex. 14: (isoBu)2Sn(F)(CH2)3OH; Ex. 16: (nBu)2Sn(Cl)-N(nBu)CH2Ph.

Abstract translation: 含有卤素的有机锡化合物是通过有机锡卤化物与具有不饱和基团的化合物（例如烯烃，炔烃，醛，酮，不饱和腈，希夫碱和偶氮化合物）反应而制备的，优选在自由基产生催化剂存在下 （例如苄基低腈，偶氮异丁腈或偶氮异丁基二烷基酯）在惰性气氛（N 2）中，在或不用溶剂下在小于50℃下进行。 式R2Sn（X）H，RSn（X）H2或RSn（X2）H（优选其中R = C1-C8烷基或简单芳基，例如Ph）的烷基，芳基或芳烷基锡卤素原位从相应的 有机锡氢化物和有机锡卤化物，并且可以与不饱和化合物反应，得到具有不同有机基团和/或含有官能团的有机锡卤化物。 Sn-H组增加了多重键。 以下化合物是实施例中制备的化合物： 2：（异丁基）2Sn（Br）-CH 2 -CH 2 CN; 例如 3：Ph 2 Sn（Cl）-CH 2 -CHMePh; 例如 5：Ph2Sn（Cl）（CH2）6-Sn（Cl）Ph2; 例如 6：（nBu）2Sn（Cl）（CH 2）3 O（CH 2）2 OH; 例如 11：EtSn（Br）2CH = CHPh; 例如 14：（异丁基）2Sn（F）（CH 2）3 OH; 例如 16：（nBu）2Sn（Cl）-N（nBu）CH 2 Ph。