公开(公告)号：US20240166806A1

公开(公告)日：2024-05-23

申请号：US18282470

申请日：2022-03-17

申请人： SULZER MANAGEMENT AG

发明人： Ho Ting Harris LUK ,  Matteo MARALDI

IPC分类号： C08G63/78 ,  C08G63/08

CPC分类号： C08G63/785 ,  C08G63/08

摘要： A process of continuously manufacturing a poly(hydroxy acid) copolymer is provided. The process comprises copolymerizing at least two different monomers in the presence of a catalyst in a reactor system by ring-opening-polymerization. At least one of the monomers is a cyclic ester of hydroxy acid. A molar ratio of a total amount of the different monomers to a total amount of the at least one catalyst is more than 10,000. The reactor system comprises in series at least two polymerization reactors including a continuous stirred-tank reactor, a loop reactor or a plug flow reactor, one of the reactors comprising at least one of a mixer and a heat transfer element. The reactor system comprises at least two different feeding points through each of which a monomer composition is fed. A first monomer composition fed through one feeding point is different from a second monomer composition fed through another feeding point.