公开(公告)号：US20150150858A1

公开(公告)日：2015-06-04

申请号：US14320414

申请日：2014-06-30

Applicant: SUNESIS PHARMACEUTICALS, INC.

Inventor： Daniel C. ADELMAN ,  Marc J. EVANCHIK ,  Anantha SUDHAKAR ,  Jeffrey William JACOBS ,  Jeffrey A. SILVERMAN

IPC: A61K31/4375

CPC classification number: C07D471/04 ,  A61K31/4375 ,  A61K31/4745 ,  C07D417/14 ,  A61K2300/00

Abstract: Compounds and compositions for treating, preventing or managing cancer are disclosed. The compositions provided herein comprise SNS-595 and N-desmethyl-SNS-595. Also provided are pharmaceutical compositions comprising the compounds and methods of treatment using the compounds and compositions.

Abstract translation: 公开了用于治疗，预防或控制癌症的化合物和组合物。 本文提供的组合物包含SNS-595和N-去甲基-SNS-595。 还提供了包含化合物的药物组合物和使用该化合物和组合物的治疗方法。