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1.发明申请公开(公告)号：US20150299118A1
公开(公告)日：2015-10-22
申请号：US14378975
申请日：2013-06-25
发明人： Zheng Gu , Guanpeng Qiu , Wuyong Wu , Panpan Kang , Zongyuan Zhang , Gang Chen , Chengsheng Lan , Yonggang Wei , Jiaping Wen , Guozhi Zhu , Yonghua Lu , Heran Wang , Yincai Wang , Mingyun Yuan , Kangzhi Ye , Guizhuan Su , PengCho Tang
IPC分类号： C07D207/16 , A61K31/40 , C07D405/12 , C07D209/52 , A61K31/403 , C07C217/52 , A61K45/06
CPC分类号： C07D207/16 , A61K31/40 , A61K31/4025 , A61K31/403 , A61K45/06 , C07C213/02 , C07C217/52 , C07C249/08 , C07C253/30 , C07C255/47 , C07C2601/02 , C07C2602/22 , C07C2603/94 , C07D209/52 , C07D405/12 , C07C251/34 , A61K2300/00
摘要： The invention relates to hexahydropentaleno derivatives, the preparation method and use in medicine thereof, and in particular to hexahydropentaleno derivatives or stereo-isomers or pharmaceutically acceptable salts thereof as shown in general formula (I), and to the preparation method therefor and pharmaceutical compositions comprising the derivatives, and to the use thereof as a therapeutical agent, especially as a DPP-IV inhibitor. The definition of each substituent in formula (I) is the same as the definition in the description.
摘要翻译： 本发明涉及六氢蛇嘌呤衍生物，其制备方法及其药物用途，特别是通式（I）所示的六氢蛇嘌呤衍生物或立体异构体或其药学上可接受的盐及其制备方法和药物组合物，其包含 衍生物和其作为治疗剂的用途，特别是作为DPP-IV抑制剂。 式（I）中每个取代基的定义与描述中的定义相同。
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2.发明授权公开(公告)号：US09567300B2
公开(公告)日：2017-02-14
申请号：US14378975
申请日：2013-06-25
发明人： Zheng Gu , Guanpeng Qiu , Wuyong Wu , Panpan Kang , Zongyuan Zhang , Gang Chen , Chengsheng Lan , Yonggang Wei , Jiaping Wen , Guozhi Zhu , Yonghua Lu , Heran Wang , Yincai Wang , Mingyun Yuan , Kangzhi Ye , Guizhuan Su , PengCho Tang
IPC分类号： C07D207/16 , A61K31/40 , C07D405/12 , C07D209/52 , A61K31/403 , C07C217/52 , A61K45/06 , C07C255/47 , C07C213/02 , C07C253/30 , C07C249/08 , A61K31/4025
CPC分类号： C07D207/16 , A61K31/40 , A61K31/4025 , A61K31/403 , A61K45/06 , C07C213/02 , C07C217/52 , C07C249/08 , C07C253/30 , C07C255/47 , C07C2601/02 , C07C2602/22 , C07C2603/94 , C07D209/52 , C07D405/12 , C07C251/34 , A61K2300/00
摘要： The invention relates to hexahydropentaleno derivatives, the preparation method and use in medicine thereof, and in particular to hexahydropentaleno derivatives or stereo-isomers or pharmaceutically acceptable salts thereof as shown in general formula (I), and to the preparation method therefor and pharmaceutical compositions comprising the derivatives, and to the use thereof as a therapeutical agent, especially as a DPP-IV inhibitor. The definition of each substituent in formula (I) is the same as the definition in the description.
摘要翻译： 本发明涉及六氢蛇嘌呤衍生物，其制备方法及其药物用途，特别是通式（I）所示的六氢蛇嘌呤衍生物或立体异构体或其药学上可接受的盐及其制备方法和药物组合物，其包含 衍生物和其作为治疗剂的用途，特别是作为DPP-IV抑制剂。 式（I）中每个取代基的定义与描述中的定义相同。
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