公开(公告)号：US20220267346A1

公开(公告)日：2022-08-25

申请号：US17624572

申请日：2019-07-02

Applicant: SUNSHINE LAKE PHARMA CO., LTD.

Inventor： Zheng GU ,  Wanjun TANG ,  Xinye YANG ,  Xuli WANG ,  Weihui YUAN ,  Yunzeng CUI ,  Wen YANG ,  Jianyu LIU ,  Yingjun ZHANG

IPC: C07D495/04

Abstract: Thienopyrimidine derivative having stereo configurations and use thereof in medicine. Also included are pharmaceutical compositions of the compounds. The compounds or pharmaceutical compositions may be used to inhibit acetyl-CoA carboxylase (ACC). A method for preparing the compounds and the pharmaceutical compositions, and use thereof in treatment or prevention of diseases associated with ACC regulation of mammals, in particular, humans.