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1.发明公开公开(公告)号：US20240197768A1
公开(公告)日：2024-06-20
申请号：US18238836
申请日：2023-08-28
申请人： SYNEDGEN, INC.
IPC分类号： A61K31/722 , A61K9/00
CPC分类号： A61K31/722 , A61K9/0014 , A61K9/0043 , A61K9/0053 , Y02A50/30
摘要： Described herein are methods of disrupting (e.g., reducing the viscosity of, or dissolving) a preformed biofilm in a subject, the method comprising: administering to the subject an effective amount of a composition comprising a soluble chitosan or derivatized chitosan wherein the soluble chitosan or derivatized chitosan when administered contacts the preformed biofilm, thereby disrupting (e.g., reducing the viscosity of, or dissolving) the preformed biofilm.
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2.发明申请公开(公告)号：US20200009182A1
公开(公告)日：2020-01-09
申请号：US16572053
申请日：2019-09-16
申请人： SYNEDGEN, INC.
IPC分类号： A61K31/722 , A61K9/00
摘要： Described herein are methods of disrupting (e.g., reducing the viscosity of, or dissolving) a preformed biofilm in a subject, the method comprising: administering to the subject an effective amount of a composition comprising a soluble chitosan or derivatized chitosan wherein the soluble chitosan or derivatized chitosan when administered contacts the preformed biofilm, thereby disrupting (e.g., reducing the viscosity of, or dissolving) the preformed biofilm.
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3.发明申请ORAL CARE METHODS AND COMPOSITIONS UTILIZING CHITOSAN-DERIVATIVE COMPOUNDS 审中-公开口服护理方法和使用化合物衍生化合物的组合物公开(公告)号：US20150224044A1
公开(公告)日：2015-08-13
申请号：US14495192
申请日：2014-09-24
申请人： SYNEDGEN, INC.
CPC分类号： A61K8/736 , A61K2800/30 , A61Q11/00 , A61Q11/02 , A61Q17/005
摘要： Described herein is a method of reducing bacteria in the mouth of a subject, the method comprising contacting (e.g., rinsing) the mouth with an effective amount of a composition comprising a soluble derivatized chitosan, thereby reducing bacteria in the mouth of the subject.
摘要翻译： 本文描述的是减少受试者口腔中的细菌的方法，该方法包括使口部接触（例如，漂洗）有效量的包含可溶性衍生化壳聚糖的组合物，从而减少受试者口腔中的细菌。
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公开(公告)号：US11957707B2
公开(公告)日：2024-04-16
申请号：US16573559
申请日：2019-09-17
申请人： SYNEDGEN, INC.
CPC分类号： A61K31/726 , A61K9/0078 , A61K9/08 , A61K9/14 , A61K9/48 , A61K45/06 , A61K47/10
摘要： Described herein are methods for treating or preventing a disease or disorder of the pulmonary system (e.g., cystic fibrosis), respiratory or digestive system in a subject, the methods comprising administering compounds or compositions comprising water soluble polyglucosamine and derivatized polyglucosamine.
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公开(公告)号：US20200009183A1
公开(公告)日：2020-01-09
申请号：US16573559
申请日：2019-09-17
申请人： SYNEDGEN, INC.
摘要： Described herein are methods for treating or preventing a disease or disorder of the pulmonary system (e.g., cystic fibrosis), respiratory or digestive system in a subject, the methods comprising administering compounds or compositions comprising water soluble polyglucosamine and derivatized polyglucosamine.
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公开(公告)号：US20170304355A1
公开(公告)日：2017-10-26
申请号：US15510478
申请日：2015-09-11
申请人： SYNEDGEN, INC.
CPC分类号： A61K31/726 , A61K9/0078 , A61K9/08 , A61K9/14 , A61K9/48 , A61K45/06 , A61K47/10
摘要： Described herein are methods for treating or preventing a disease or disorder of the pulmonary system (e.g., cystic fibrosis), respiratory or digestive system in a subject, the methods comprising administering compounds or compositions comprising water soluble polyglucosamine and derivatized polyglucosamine.
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公开(公告)号：US20240350529A1
公开(公告)日：2024-10-24
申请号：US18588605
申请日：2024-02-27
申请人： SYNEDGEN, INC.
CPC分类号： A61K31/726 , A61K9/0078 , A61K9/08 , A61K9/14 , A61K9/48 , A61K45/06 , A61K47/10
摘要： Described herein are methods for treating or preventing a disease or disorder of the pulmonary system (e.g., cystic fibrosis), respiratory or digestive system in a subject, the methods comprising administering compounds or compositions comprising water soluble polyglucosamine and derivatized polyglucosamine.
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公开(公告)号：US11786547B2
公开(公告)日：2023-10-17
申请号：US16572053
申请日：2019-09-16
申请人： SYNEDGEN, INC.
IPC分类号： A61K31/722 , A61K9/00
CPC分类号： A61K31/722 , A61K9/0014 , A61K9/0043 , A61K9/0053 , Y02A50/30
摘要： Described herein are methods of disrupting (e.g., reducing the viscosity of, or dissolving) a preformed biofilm in a subject, the method comprising: administering to the subject an effective amount of a composition comprising a soluble chitosan or derivatized chitosan wherein the soluble chitosan or derivatized chitosan when administered contacts the preformed biofilm, thereby disrupting (e.g., reducing the viscosity of, or dissolving) the preformed biofilm.
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公开(公告)号：US20230021050A1
公开(公告)日：2023-01-19
申请号：US17669766
申请日：2022-02-11
申请人： SYNEDGEN, INC.
IPC分类号： A61K31/726 , A61L2/232 , A61K31/722 , A61P1/14 , A61P1/00 , A61K9/00 , A61K47/10
摘要： Provided herein are methods of treating (e.g., inhibiting, modulating, reversing, or reducing the severity of at least one symptom of) a dysbiosis in a subject, the method comprising administering an effective amount of a composition described herein (e.g., a composition comprising polyglucosamine-arginine (PAAG)).
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公开(公告)号：US20190070214A1
公开(公告)日：2019-03-07
申请号：US16085213
申请日：2017-03-16
申请人： SYNEDGEN, INC.
IPC分类号： A61K31/726 , A61P1/00 , A61K9/00 , A61K47/10 , A61P1/14
摘要： Provided herein are methods of treating (e.g., inhibiting, modulating, reversing, or reducing the severity of at least one symptom of) a dysbiosis in a subject, the method comprising administering an effective amount of a composition described herein (e.g., a composition comprising polyglucosamine-arginine (PAAG)).
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