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公开(公告)号：US08010202B2
公开(公告)日：2011-08-30
申请号：US11943487
申请日：2007-11-20
申请人： Samip Shah , Amy Chu Peishuan Hines , Dao Min Zhou , Robert J. Greenberg , Mark S. Humayun , James D. Weiland
发明人： Samip Shah , Amy Chu Peishuan Hines , Dao Min Zhou , Robert J. Greenberg , Mark S. Humayun , James D. Weiland
IPC分类号： A61N1/00
CPC分类号： A61N1/0543
摘要： A critical element of a retinal prosthesis is the stimulating electrode array, which is placed in close proximity to the retina. It is via this interface that a retinal prosthesis electrically stimulates nerve cells to produce the perception of light. The impedance load seen by the current driver consists of the tissue resistance and the complex electrode impedance. The results show that the tissue resistance of the retina is significantly greater than that of the vitreous humor in the eye. Circuit models of the electrode-retina interface are used to parameterize the different contributors to the overall impedance.
摘要翻译： 视网膜假体的关键元件是刺激电极阵列，其被放置在靠近视网膜的位置。 通过该界面，视网膜假体电刺激神经细胞产生光的感知。 电流驱动器所看到的阻抗由组织电阻和复合电极阻抗组成。 结果表明，视网膜的组织电阻显着大于眼玻璃体液的组织电阻。 电极 - 视网膜界面的电路模型用于参数化整个阻抗的不同贡献者。
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公开(公告)号：US20080119908A1
公开(公告)日：2008-05-22
申请号：US11943487
申请日：2007-11-20
申请人： Samip Shah , Amy Chu Peishuan Hines , Dao Min Zhou , Robert J. Greenberg , Mark S. Humayun , James D. Weiland
发明人： Samip Shah , Amy Chu Peishuan Hines , Dao Min Zhou , Robert J. Greenberg , Mark S. Humayun , James D. Weiland
IPC分类号： A61N1/05
CPC分类号： A61N1/0543
摘要： A critical element of a retinal prosthesis is the stimulating electrode array, which is placed in close proximity to the retina. It is via this interface that a retinal prosthesis electrically stimulates nerve cells to produce the perception of light. The impedance load seen by the current driver consists of the tissue resistance and the complex electrode impedance. The results show that the tissue resistance of the retina is significantly greater than that of the vitreous humor in the eye. Circuit models of the electrode-retina interface are used to parameterize the different contributors to the overall impedance.
摘要翻译： 视网膜假体的关键元件是刺激电极阵列，其被放置在靠近视网膜的位置。 通过该界面，视网膜假体电刺激神经细胞产生光的感知。 电流驱动器所看到的阻抗由组织电阻和复合电极阻抗组成。 结果表明，视网膜的组织电阻显着大于眼玻璃体液的组织电阻。 电极 - 视网膜界面的电路模型用于参数化整个阻抗的不同贡献者。
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公开(公告)号：US08239036B2
公开(公告)日：2012-08-07
申请号：US13179186
申请日：2011-07-08
申请人： Samip Shah , Amy Chu Peishuan Hines , Dao Min Zhou , Robert J. Greenberg , Mark S. Humayun , James D. Weiland
发明人： Samip Shah , Amy Chu Peishuan Hines , Dao Min Zhou , Robert J. Greenberg , Mark S. Humayun , James D. Weiland
IPC分类号： A61N1/18
CPC分类号： A61N1/0543
摘要： A critical element of a retinal prosthesis is the stimulating electrode array, which is placed in close proximity to the retina. It is via this interface that a retinal prosthesis electrically stimulates nerve cells to produce the perception of light. The impedance load seen by the current driver consists of the tissue resistance and the complex electrode impedance. The results show that the tissue resistance of the retina is significantly greater than that of the vitreous humor in the eye. Circuit models of the electrode-retina interface are used to parameterize the different contributors to the overall impedance.
摘要翻译： 视网膜假体的关键元件是刺激电极阵列，其被放置在靠近视网膜的位置。 通过该界面，视网膜假体电刺激神经细胞产生光的感知。 电流驱动器所看到的阻抗由组织电阻和复合电极阻抗组成。 结果表明，视网膜的组织电阻显着大于眼玻璃体液的组织电阻。 电极 - 视网膜界面的电路模型用于参数化整个阻抗的不同贡献者。
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公开(公告)号：US20110282413A1
公开(公告)日：2011-11-17
申请号：US13179186
申请日：2011-07-08
申请人： Samip Shah , Amy Chu Peishuan Hines , Dao Min Zhou , Robert J. Greenberg , Mark S. Humayun , James D. Weiland
发明人： Samip Shah , Amy Chu Peishuan Hines , Dao Min Zhou , Robert J. Greenberg , Mark S. Humayun , James D. Weiland
CPC分类号： A61N1/0543
摘要： A critical element of a retinal prosthesis is the stimulating electrode array, which is placed in close proximity to the retina. It is via this interface that a retinal prosthesis electrically stimulates nerve cells to produce the perception of light. The impedance load seen by the current driver consists of the tissue resistance and the complex electrode impedance. The results show that the tissue resistance of the retina is significantly greater than that of the vitreous humor in the eye. Circuit models of the electrode-retina interface are used to parameterize the different contributors to the overall impedance.
摘要翻译： 视网膜假体的关键元件是刺激电极阵列，其被放置在靠近视网膜的位置。 通过该界面，视网膜假体电刺激神经细胞产生光的感知。 电流驱动器所看到的阻抗由组织电阻和复合电极阻抗组成。 结果表明，视网膜的组织电阻显着大于眼玻璃体液的组织电阻。 电极 - 视网膜界面的电路模型用于参数化整个阻抗的不同贡献者。
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公开(公告)号：US08571671B2
公开(公告)日：2013-10-29
申请号：US13540137
申请日：2012-07-02
申请人： Samip Shah , Amy Chu Peishuan Hines , Dao Min Zhou , Robert J. Greenberg , Mark S. Humayun , James D. Weiland
发明人： Samip Shah , Amy Chu Peishuan Hines , Dao Min Zhou , Robert J. Greenberg , Mark S. Humayun , James D. Weiland
IPC分类号： A61N1/36
CPC分类号： A61N1/0543
摘要： A critical element of a retinal prosthesis is the stimulating electrode array, which is placed in close proximity to the retina. It is via this interface that a retinal prosthesis electrically stimulates nerve cells to produce the perception of light. The impedance load seen by the current driver consists of the tissue resistance and the complex electrode impedance. The results show that the tissue resistance of the retina is significantly greater than that of the vitreous humor in the eye. Circuit models of the electrode-retina interface are used to parameterize the different contributors to the overall impedance.
摘要翻译： 视网膜假体的关键元件是刺激电极阵列，其被放置在靠近视网膜的位置。 通过该界面，视网膜假体电刺激神经细胞产生光的感知。 电流驱动器所看到的阻抗由组织电阻和复合电极阻抗组成。 结果表明，视网膜的组织电阻显着大于眼玻璃体液的组织电阻。 电极 - 视网膜界面的电路模型用于参数化整个阻抗的不同贡献者。
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公开(公告)号：US20120277620A1
公开(公告)日：2012-11-01
申请号：US13540137
申请日：2012-07-02
申请人： Samip Shah , Amy Chu Peishuan Hines , Dao Min Zhou , Robert J. Greenberg , Mark S. Humayun , James D. Weiland
发明人： Samip Shah , Amy Chu Peishuan Hines , Dao Min Zhou , Robert J. Greenberg , Mark S. Humayun , James D. Weiland
IPC分类号： A61B5/053
CPC分类号： A61N1/0543
摘要： A critical element of a retinal prosthesis is the stimulating electrode array, which is placed in close proximity to the retina. It is via this interface that a retinal prosthesis electrically stimulates nerve cells to produce the perception of light. The impedance load seen by the current driver consists of the tissue resistance and the complex electrode impedance. The results show that the tissue resistance of the retina is significantly greater than that of the vitreous humor in the eye. Circuit models of the electrode-retina interface are used to parameterize the different contributors to the overall impedance.
摘要翻译： 视网膜假体的关键元件是刺激电极阵列，其被放置在靠近视网膜的位置。 通过这个界面，视网膜假体电刺激神经细胞产生光的感知。 电流驱动器所看到的阻抗由组织电阻和复合电极阻抗组成。 结果表明，视网膜的组织电阻显着大于眼玻璃体液的组织电阻。 电极 - 视网膜界面的电路模型用于参数化整个阻抗的不同贡献者。
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公开(公告)号：US10065036B2
公开(公告)日：2018-09-04
申请号：US11906167
申请日：2007-09-28
摘要： The present invention is a method for measuring stable and reproducible electrode-tissue impedance, comprising preconditioning an electrode-tissue interface. Further aspect of the invention is a stimulation system for a visual prosthesis generating a stimulation signal to precondition the electrode-tissue interface, comprising a computer; software, loaded in the computer, adapted to perform a stimulating method for a visual prosthesis having a plurality of electrodes; a video processing unit; and an implanted neuron-stimulator.
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公开(公告)号：US09802045B2
公开(公告)日：2017-10-31
申请号：US11924436
申请日：2007-10-25
IPC分类号： A61N1/36
CPC分类号： A61N1/36046 , A61N1/0543
摘要： The present invention is a method for measuring stable and reproducible electrode-tissue impedance, comprising preconditioning an electrode-tissue interface. Further aspect of the invention is a stimulation system for a visual prosthesis generating a stimulation signal to precondition the electrode-tissue interface, comprising a computer; software, loaded in the computer, adapted to perform a stimulating method for a visual prosthesis having a plurality of electrodes; a video processing unit; and an implanted neuron-stimulator.
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9.发明申请公开(公告)号：US20080275362A1
公开(公告)日：2008-11-06
申请号：US11924436
申请日：2007-10-25
IPC分类号： A61B5/053
CPC分类号： A61N1/36046 , A61N1/0543
摘要： The present invention is a method for measuring stable and reproducible electrode-tissue impedance, comprising preconditioning an electrode-tissue interface. Further aspect of the invention is a stimulation system for a visual prosthesis generating a stimulation signal to precondition the electrode-tissue interface, comprising a computer; software, loaded in the computer, adapted to perform a stimulating method for a visual prosthesis having a plurality of electrodes; a video processing unit; and an implanted neuron-stimulator.
摘要翻译： 本发明是一种用于测量稳定且可再现的电极组织阻抗的方法，包括预处理电极 - 组织界面。 本发明的另一方面是一种用于视觉假体的刺激系统，其产生用于预处理电极 - 组织界面的刺激信号，所述刺激信号包括计算机; 软件，装在计算机中，适用于执行具有多个电极的视觉假体的刺激方法; 视频处理单元; 和植入的神经元刺激器。
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10.发明申请公开(公告)号：US20080082140A1
公开(公告)日：2008-04-03
申请号：US11906167
申请日：2007-09-28
IPC分类号： A61N1/00
CPC分类号： A61N1/36046 , A61N1/0543
摘要： The present invention is a method for measuring stable and reproducible electrode-tissue impedance, comprising preconditioning an electrode-tissue interface. Further aspect of the invention is a stimulation system for a visual prosthesis generating a stimulation signal to precondition the electrode-tissue interface, comprising a computer; software, loaded in the computer, adapted to perform a stimulating method for a visual prosthesis having a plurality of electrodes; a video processing unit; and an implanted neuron-stimulator.
摘要翻译： 本发明是一种用于测量稳定且可再现的电极组织阻抗的方法，包括预处理电极 - 组织界面。 本发明的另一方面是一种用于视觉假体的刺激系统，其产生用于预处理电极 - 组织界面的刺激信号，所述刺激信号包括计算机; 软件，装在计算机中，适用于执行具有多个电极的视觉假体的刺激方法; 视频处理单元; 和植入的神经元刺激器。
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