公开(公告)号：US20230025836A1

公开(公告)日：2023-01-26

申请号：US17756266

申请日：2020-11-20

Applicant: Samjin Pharmaceutical Co., Ltd. ,  AptaBio Therapeutics Inc.

Inventor： Min-hyo Ki ,  Jin-cheul Kim ,  Mee-Hwa Choi ,  Dong-Ha Lee ,  Sung Hwan Moon ,  Soo Jin Lee

IPC: A61K31/4155 ,  A61K9/00 ,  A61P27/02

Abstract: The present invention relates to an ophthalmic preparation containing an active ingredient selected from 3-phenyl-4-propyl-1-(pyridin-2-yl)-1H-pyrazol-5-ol compound or a pharmaceutically acceptable salt thereof. The eye drop according to the present invention is excellent in stability and safety and shows an excellent effect on prevention or treatment of eye diseases in such a way that an active ingredient thereof reaches a posterior segment of an eyeball simply through instillation rather than a direct injection into an eyeball.

公开(公告)号：US20220218685A1

公开(公告)日：2022-07-14

申请号：US17614705

申请日：2020-05-29

Applicant: Samjin Pharmaceutical Co., Ltd. ,  AptaBio Therapeutics Inc.

Inventor： Min-hyo Ki ,  Kyung-wan Nam ,  Jin-cheul Kim ,  Kyung-jin Ahn ,  Sung Hwan Moon ,  Soo Jin Lee

IPC: A61K31/4439 ,  A61K47/34 ,  A61K9/00 ,  A61P27/02

Abstract: The present invention relates to a composition for treating eye diseases, wherein the composition comprises a pyrazole-based compound, which is a pharmacologically active substance, and a biodegradable polymer, so that a drug effectively reaches a posterior segment of an eyeball, while prolonging an action time of the drug administered into the eyeball.