公开(公告)号：US09598726B2

公开(公告)日：2017-03-21

申请号：US13900629

申请日：2013-05-23

Applicant: Samsung Electronics Co., Ltd.

Inventor： Sung-hong Kwon ,  Sung-min Chi ,  Kyu-youn Hwang ,  Joon-ho Kim ,  Sun-ok Jung ,  Sung-ouk Jung ,  Won-jong Jung

IPC: C12Q1/68 ,  C07H21/04

CPC classification number: C12Q1/6848 ,  C12Q2527/125 ,  C12Q2563/137

Abstract: A method for amplifying a nucleic acid amplification in the presence of an ionic liquid that suppresses an inhibitor of nucleic acid amplification, particularly when in a biological material, and a composition useful for performing the method.

公开(公告)号：US09139872B2

公开(公告)日：2015-09-22

申请号：US13754628

申请日：2013-01-30

Applicant: Samsung Electronics Co., Ltd.

Inventor： Kyung-ho Kim ,  Soo-kwan Lee ,  Joon-ho Kim ,  Kak Namkoong ,  Sun-ok Jung ,  Won-seok Chung

IPC: C12Q1/68

CPC classification number: C12Q1/686 ,  C12Q1/68 ,  C12Q1/6848 ,  C12Q2537/165 ,  C12Q2563/107

Abstract: A method of analyzing nucleic acid by compensating for crosstalk in polymerase chain reaction (PCR) data and other data, wherein crosstalk signals associated with multiple fluorescent dyes are corrected by using fluorescent intensity variations detected from a concentration difference of the fluorescent dyes, and apparatus for performing the method.

Abstract translation: 通过补偿聚合酶链反应（PCR）数据和其他数据中的串扰来分析核酸的方法，其中通过使用从荧光染料的浓度差检测的荧光强度变化来校正与多种荧光染料相关联的串扰信号，以及用于 执行该方法。

公开(公告)号：US09428798B2

公开(公告)日：2016-08-30

申请号：US14273790

申请日：2014-05-09

Applicant: Samsung Electronics Co., Ltd.

Inventor： Sea-hee Kim ,  Joon-ho Kim ,  Joo-won Rhee ,  Sun-ok Jung ,  Ko-bong Choi ,  Kyu-youn Hwang

IPC: C12Q1/68 ,  C07H21/02

CPC classification number: C12Q1/6848 ,  C12Q2521/327 ,  C12Q2525/186 ,  C12Q2525/301

Abstract: A polynucleotide comprising a first region the 5′ end of which is complementary to a portion of a target nucleic acid, a cleavable second region, a third region having a stem-loop structure, and a fourth region complementary to the 3′ end of the first region, and use of the polynucleotide, as well as a composition comprising two such polynucleotides each of which hybridize different strands of a double-stranded target nucleic acid, and methods and kits using the same for amplifying targets.

Abstract translation: 一种多核苷酸，其包含其5'末端与靶核酸的一部分互补的第一区域，可切割第二区域，具有茎环结构的第三区域和与所述第三区域的3'末端互补的第四区域 第一区域和多核苷酸的使用，以及包含两个这样的多核苷酸的组合物，其各自与双链靶核酸的不同链杂交，以及将其用于扩增靶标的方法和试剂盒。

公开(公告)号：US20150080241A1

公开(公告)日：2015-03-19

申请号：US14273790

申请日：2014-05-09

Applicant: Samsung Electronics Co., Ltd.

Inventor： Sea-hee KIM ,  Joon-ho Kim ,  Joo-won Rhee ,  Sun-ok Jung ,  Ko-bong Choi ,  Kyu-youn Hwang

IPC: C12Q1/68

CPC classification number: C12Q1/6848 ,  C12Q2521/327 ,  C12Q2525/186 ,  C12Q2525/301

Abstract: A polynucleotide comprising a first region the 5′ end of which is complementary to a portion of a target nucleic acid, a cleavable second region, a third region having a stem-loop structure, and a fourth region complementary to the 3′ end of the first region, and use of the polynucleotide, as well as a composition comprising two such polynucleotides each of which hybridize different strands of a double-stranded target nucleic acid, and methods and kits using the same for amplifying targets.

Abstract translation: 一种多核苷酸，其包含其5'末端与靶核酸的一部分互补的第一区域，可切割第二区域，具有茎环结构的第三区域和与所述第三区域的3'末端互补的第四区域 第一区域和多核苷酸的使用，以及包含两个这样的多核苷酸的组合物，其各自与双链靶核酸的不同链杂交，以及将其用于扩增靶标的方法和试剂盒。

公开(公告)号：US09133526B2

公开(公告)日：2015-09-15

申请号：US13754609

申请日：2013-01-30

Applicant: Samsung Electronics Co., Ltd.

Inventor： Sun-ok Jung ,  Joon-ho Kim ,  Soo-kwan Lee ,  Kyu-youn Hwang ,  Tae-hee Um

IPC: C12Q1/68 ,  C12P19/34

CPC classification number: C12Q1/689 ,  C12Q2600/156

Abstract: A composition and kit for detecting Clostridium difficile including a primer set for detecting a strain of Clostridium difficile, and a method of detecting Clostridium difficile by using the same.

Abstract translation: 一种用于检测艰难梭菌的组合物和试剂盒，其包括用于检测艰难梭菌菌株的引物组，以及通过使用该艰难梭菌检测艰难梭菌的方法。