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公开(公告)号:US20170157145A1
公开(公告)日:2017-06-08
申请号:US15332306
申请日:2016-10-24
发明人: Yunil Lee , Yunjong Lee , Sangwoo Ham , Sangchul Park , Jooho Shin
IPC分类号: A61K31/573 , G01N33/50 , C12N9/00 , A61K31/4196 , A61K31/407
CPC分类号: A61K31/573 , A61K31/407 , A61K31/4196 , C12N9/93 , C12Y603/02 , G01N33/5023 , G01N33/5058 , G01N33/6896 , G01N2333/9015 , G01N2800/2814 , G01N2800/2835
摘要: A method of inducing Parkin expression; inhibiting oxidative stress; and inhibiting cell death of cells by administering deferasirox, hydrocortisone, ketorolac, dexamethasone, and prednisone, a pharmaceutically acceptable salt, stereoisomer, derivative, or solvate thereof to the cell, optionally in a subject, as well as a method of preventing or treating neurodegenerative disease in the subject.