专利检索 ap:("Samuel J. Danishefsky" OR "Shawn J. Stachel" OR "Chul Bom Lee" OR "Mark D. Chappell" OR "Zhical Wu") AND inv:"Mark D. Chappell" 第 1 页

1.

发明授权
Synthesis of epothilones, intermediates thereto and analogues thereof 失效
标题翻译：埃坡霉素的合成，其中间体及其类似物

公开(公告)号：US06867305B2

公开(公告)日：2005-03-15

申请号：US09796959

申请日：2001-03-01

申请人： Samuel J. Danishefsky , Shawn J. Stachel , Chul Bom Lee , Mark D. Chappell , Zhical Wu

发明人： Samuel J. Danishefsky , Shawn J. Stachel , Chul Bom Lee , Mark D. Chappell , Zhical Wu

IPC分类号： A61K31/337 , A61K31/475 , A61K45/06 , C07D277/30 , C07D417/06 , C07D263/32

CPC分类号： C07D417/06 , A61K31/337 , A61K31/475 , A61K45/06 , A61K2300/00

摘要： The present invention provides convergent processes for preparing epothilones, desoxyepothilones, and analogues thereof. The present invention further provides novel compositions and methods for the treatment of cancer and additionally provides methods for the treatment of cancer which has developed a multi-drug phenotype.

摘要翻译： 本发明提供用于制备埃坡霉素，脱氧头孢烯酮及其类似物的收敛方法。本发明还提供了用于治疗癌症的新型组合物和方法，并且另外提供了治疗已发展成多种药物表型的癌症的方法。