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公开(公告)号:US20110086348A1
公开(公告)日:2011-04-14
申请号:US12709010
申请日:2010-02-19
申请人: Sathyamangla V. Naga Prasad , Sadashiva Karnik , Carlo Croce , Dianne M. Perez , Edward Plow , Christine Moravec , Subha Sen , Qingyu Wu , Randall C. Starling
发明人: Sathyamangla V. Naga Prasad , Sadashiva Karnik , Carlo Croce , Dianne M. Perez , Edward Plow , Christine Moravec , Subha Sen , Qingyu Wu , Randall C. Starling
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6883 , C12Q2600/112 , C12Q2600/156 , C12Q2600/158 , C12Q2600/178
摘要: A method for assessing heart disease in a subject includes generating an expression profile of at least two or more miRNAs in a sample from the subject. The miRNAs can be selected from the group consisting of hsa-miRNA-1, hsa-miRNA-7, hsa-miRNA-29b, has-miRNA-125b, hsa-miRNA145, hsa-miRNA-181b, hsa-miRNA-214, hsa-miRNA-342, hsa-miRNA-378 and combinations thereof.
摘要翻译: 用于评估受试者心脏病的方法包括在受试者的样品中产生至少两种或更多种miRNA的表达谱。 miRNA可以选自hsa-miRNA-1,hsa-miRNA-7,hsa-miRNA-29b,has-miRNA-125b,hsa-miRNA145,hsa-miRNA-181b,hsa-miRNA-214, hsa-miRNA-342,hsa-miRNA-378及其组合。