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公开(公告)号:US07074818B2
公开(公告)日:2006-07-11
申请号:US10483580
申请日:2002-01-07
申请人: Satyanarayana Reddy Manne , Nagaraju Chakilam , Srinivasulu Gudipati , Srinivas Katkam , Rajeswar Reddy Sagyam
发明人: Satyanarayana Reddy Manne , Nagaraju Chakilam , Srinivasulu Gudipati , Srinivas Katkam , Rajeswar Reddy Sagyam
IPC分类号: A61K31/40 , C07D207/00
CPC分类号: C07D207/34
摘要: The present invention relates to novel crystalline forms of atorvastatin calcium and to the methods of their production and isolation. More specifically, the present invention relates to novel Forms VI and VII of R—(R*,R*)]-2(4-fluorophenyl)-B,d dihydroxy-5(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1-H-pyrrole-1-heptanoic- acid calcium salt and hydrates thereof and to methods of their preparation.
摘要翻译: 本发明涉及阿托伐他汀钙的新型结晶形式及其生产和分离方法。 更具体地说,本发明涉及R-(R *,R *)] - 2(4-氟苯基)-B,d-二羟基-5(1-甲基乙基)-3-苯基-4- [(苯基氨基)羰基] -1-H-吡咯-1-庚酸钙盐及其水合物及其制备方法。
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公开(公告)号:US10544107B2
公开(公告)日:2020-01-28
申请号:US16315671
申请日:2017-06-30
申请人: MAITHRI DRUGS PRIVATE LIMITED , Nagaraju Chakilam , Kondana Ramprasad Achampeta , Pradeep Rebelli , Tavitayya Kondaka
IPC分类号: C07D241/20 , B01D9/00 , A61P9/12
摘要: The present invention relates to a processes for the preparation of 2-{4-[(5,6-diphenyl pyrazin-2-yl)(isopropyl)amino]butoxy}-N-(methylsulfonyl)acetamide compound of formula-1 and novel polymorphs thereof.
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