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1.发明申请AMMENDOLA/SALMONELLA ENTERICA STRAINS OF REDUCED PATHOGENICITY, METHOD FOR THEIR PREPARATION AND USES THEREOF 有权AMMENDOLA / SALMONELLA ENTERICA菌株的降低致病性，其制备方法及其用途公开(公告)号：US20090175913A1
公开(公告)日：2009-07-09
申请号：US12305609
申请日：2007-06-08
IPC分类号： A61K39/112 , C12N1/20 , C12N15/63 , C12N15/74
CPC分类号： C12N1/36 , A61K35/74 , A61K39/0275 , A61K2039/522 , A61K2039/552 , Y02A50/482
摘要： The invention concerns novel Salmonella enterica attenuated strains, characterized in that they are inactivated at the level of the znuABC operon through mutation in at least one of the znuA, znuB, znuC genes of such operon, for uses in medical or veterinary fields as vaccines.
摘要翻译： 本发明涉及新型沙门氏菌减毒菌株，其特征在于，通过在该操纵子的znuA，znuB，znuC基因中的至少一种中的突变，它们在znuABC操纵子的水平被灭活，用于医学或兽医领域中作为疫苗。
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2.发明授权Salmonella enterica strains of reduced pathogenicity, method for their preparation and uses thereof 有权沙门菌肠炎菌株致病性降低，其制备方法及其用途公开(公告)号：US08071356B2
公开(公告)日：2011-12-06
申请号：US12305609
申请日：2007-06-08
IPC分类号： C12N1/20 , A61K45/00 , A61K39/112
CPC分类号： C12N1/36 , A61K35/74 , A61K39/0275 , A61K2039/522 , A61K2039/552 , Y02A50/482
摘要： The invention concerns novel Salmonella enterica attenuated strains, characterized in that they are inactivated at the level of the znuABC operon through mutation in at least one of the znuA, znuB, znuC genes of such operon, for uses in medical or veterinary fields as vaccines.
摘要翻译： 本发明涉及新型沙门氏菌减毒菌株，其特征在于，通过在该操纵子的znuA，znuB，znuC基因中的至少一种突变，它们在znuABC操纵子的水平被灭活，用于医学或兽医领域中作为疫苗。
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