公开(公告)号：US06542628B1

公开(公告)日：2003-04-01

申请号：US09517349

申请日：2000-03-02

申请人： Serge Muller ,  Andreas Rick

发明人： Serge Muller ,  Andreas Rick

IPC分类号： G06K900

CPC分类号： G06T7/0012 ,  G06T2207/10116 ,  G06T2207/30068

摘要： Method of improved detection of elements of interest by means of a detection system in a digital radiographic image of an object, acquired on an acquisition chain, comprising a first calibration phase in which the performances of the detection system are established. For such purpose, a calibration curve with several dimensions is determined by means of a mathematical model of the acquisition chain and object, in order to express a false positive probability as a function of a set of parameters corresponding to the acquisition chain and object. In the course of a second phase of use, a false positive probability value is determined for each pixel of the image. One then selects among the pixels of the digital radiographic image acquired those whose probability value obtained satisfies a predetermined criterion.

摘要翻译： 通过在采集链上获取的对象的数字放射线照相图像中的检测系统来检测感兴趣元件的方法，包括建立检测系统的性能的第一校准阶段。 为此目的，通过采集链和物体的数学模型来确定具有若干维度的校准曲线，以便表示作为与采集链和对象相对应的一组参数的函数的假正概率。 在第二阶段使用过程中，为图像的每个像素确定假阳性概率值。 然后，在获得满足预定标准的概率值的数字放射线照相图像的像素中进行选择。

公开(公告)号：US06415015B2

公开(公告)日：2002-07-02

申请号：US09745886

申请日：2000-12-21

申请人： Francois Nicolas ,  Jean Lienard ,  Serge Muller ,  Elisabeth Soubelet ,  Andreas Rick

发明人： Francois Nicolas ,  Jean Lienard ,  Serge Muller ,  Elisabeth Soubelet ,  Andreas Rick

IPC分类号： G01N2304

CPC分类号： G06T5/009 ,  G06T5/40 ,  G06T2207/10116 ,  G06T2207/30068

摘要： Method and system for compensating for the thickness of an organ in a radiology instrument, in which an image of the radiological thicknesses of the organ through which the X-ray beam has passed is calculated on the basis of a digitized image, the thickness image is filtered using a low-pass filter in order to obtain a low-frequency image, the low-frequency image is subtracted from the radiological thickness image in order to obtain a contrast image, the low-frequency image is processed using a pre-recorded table taking into account a contract &khgr; selected by a user in order to obtain an image with reduced dynamic range, and the image with reduced dynamic range is added to the contrast image in order to obtain a compensated thickness image, the pixels having a level below or above a predetermined threshold being returned at least to the value of the threshold, while preserving the differences and real ratios between the anatomical structures.

摘要翻译： 根据数字化图像计算放射学仪器中的器官的厚度的方法和系统，其中根据数字化图像计算穿过X射线束的器官的放射学厚度的图像，厚度图像是 使用低通滤波器进行滤波以获得低频图像，从放射学厚度图像中减去低频图像以获得对比度图像，使用预先记录的表处理低频图像 考虑到一个合同＆khgr; 由用户选择以获得具有减小的动态范围的图像，并且将具有减小的动态范围的图像添加到对比度图像中，以获得补偿的厚度图像，返回低于或高于预定阈值的像素的像素返回 至少达到阈值的值，同时保留解剖结构之间的差异和实际比例。

公开(公告)号：US06304632B1

公开(公告)日：2001-10-16

申请号：US09415816

申请日：1999-10-12

申请人： Andreas Rick ,  Serge Muller ,  Jean-Luc Baudry

发明人： Andreas Rick ,  Serge Muller ,  Jean-Luc Baudry

IPC分类号： G21K100

CPC分类号： G21K1/025 ,  A61B6/06 ,  A61B6/4291

摘要： The movement of an anti-scatter grid in a radiography apparatus is a continuous curve having point symmetry with respect to the point whose time coordinate is equal to half the exposure time, and for which the space derivative of the time variable has two linear portions which are symmetrical with respect to a symmetry axis passing through the middle of the range of movement of the grid. The grid is moved with a high rate of movement close to the starting position and the end position.

摘要翻译： 放射线摄影装置中的防散射栅格的移动是相对于时间坐标等于曝光时间的一半的点的点对称的连续曲线，并且时间变量的空间导数具有两个线性部分， 相对于穿过网格运动范围中间的对称轴对称。 网格以接近起始位置和结束位置的高移动速度移动。

公开(公告)号：US06928139B2

公开(公告)日：2005-08-09

申请号：US10125312

申请日：2002-04-17

申请人： Serge Muller ,  Andreas Rick

发明人： Serge Muller ,  Andreas Rick

IPC分类号： A61B10/02 ,  A61B6/00 ,  A61B6/04

CPC分类号： A61B6/502 ,  A61B6/481

摘要： A method and device for sampling a fragment of tissue in which a contrast medium is injected into an organ to be examined and highlights parts containing that contrast medium in an image obtained by emitting a beam of X-rays. At least one pair of radiographic images is captured from a first position and a second position of an X-ray emitter during a phase of increasing attenuation due to the contrast medium. A specific area is identified from the pair of images in which a tissue fragment is to be sampled. The images of the pair of images are combined to determine the three-dimensional coordinates of the specific area.

摘要翻译： 一种将造影剂注射到待检查器官中的组织碎片采样的方法和装置，并且通过发射X射线束而获得的图像中突出包含该造影剂的部分。 由于造影剂在衰减增加的阶段中，从X射线发射器的第一位置和第二位置捕获至少一对放射照相图像。 从要对其进行采样的组织片段的一对图像中识别特定区域。 组合这对图像的图像以确定特定区域的三维坐标。

公开(公告)号：US06718056B1

公开(公告)日：2004-04-06

申请号：US09450489

申请日：1999-11-29

申请人： Sylvie Bothorel ,  Serge Muller ,  Jean Lienard ,  Andreas Rick ,  François Nicolas

发明人： Sylvie Bothorel ,  Serge Muller ,  Jean Lienard ,  Andreas Rick ,  François Nicolas

IPC分类号： G06K900

CPC分类号： G06T7/0002 ,  G06T5/009 ,  G06T5/40 ,  G06T2207/10116 ,  G06T2207/30068 ,  G06T2207/30168 ,  H04N1/4074

摘要： The method comprises a histogram of the radiographed image, i.e., a real histogram, a mathematical model of the image chain and the object obtained by calibration. The mathematical model of the image chain and the object and a set of parameters of acquisition, of the detector, of the positioner and of the object are used to determine two values of gray level, gray min and gray max, delimiting a useful zone and the part below gray min and the part above gray max are suppressed in the real histogram, i.e., a limited histogram. A set of rules is applied to the limited histogram in order to determine the level of brightness (WL) and the contrast (WW) is obtained from the brightness and possibly from one or more parameters selected by the user or fixed a priori.

摘要翻译： 该方法包括射线照相图像的直方图，即真实直方图，图像链的数学模型和通过校准获得的对象。 图像链和对象的数学模型以及采集，定位器和对象的检测参数的一组参数用于确定灰度级，灰度最小值和灰度最大值两个值，定义有用区域， 灰色最小值以下的部分和灰度最大值部分在实际直方图中被抑制，即有限的直方图。 将一组规则应用于有限直方图，以便确定亮度水平（WL），并且可以从亮度获得对比度（WW），并且可能从用户选择的一个或多个参数获得或先验固定。

公开(公告)号：US07248727B2

公开(公告)日：2007-07-24

申请号：US10153326

申请日：2002-05-22

申请人： Elisabeth Soubelet ,  Serge Muller ,  Andreas Rick

发明人： Elisabeth Soubelet ,  Serge Muller ,  Andreas Rick

IPC分类号： G06K9/00

CPC分类号： G06T5/40 ,  G06T5/007 ,  G06T2207/30068

摘要： A region of interest is selected in an input image, such as a digital or analog image form a mammography apparatus. Display parameters for the input image or a part thereof are determined as a function of the region of interest. The image or a part thereof is displayed using the determined parameters. Choosing display parameters as a function of the region of interest optimizes the display of the possible region of interest without any adjustment by the operator.

摘要翻译： 在诸如数字或模拟图像的输入图像中选择感兴趣的区域，形成乳房X线照相术装置。 输入图像或其一部分的显示参数被确定为感兴趣区域的函数。 使用确定的参数来显示图像或其一部分。 选择显示参数作为感兴趣区域的函数，可以优化显示可能的感兴趣区域，而无需操作人员进行任何调整。

公开(公告)号：US06845146B2

公开(公告)日：2005-01-18

申请号：US10218829

申请日：2002-08-14

申请人： Andreas Rick ,  Serge Muller ,  Jean-Pierre Saladin

发明人： Andreas Rick ,  Serge Muller ,  Jean-Pierre Saladin

IPC分类号： A61B6/00 ,  A61B6/04

CPC分类号： A61B6/502 ,  A61B6/0414 ,  A61B6/466

摘要： A mammography apparatus and method having an X-ray tube, an image receiver, the image receiver having one edge in contact with a patient, a compression paddle between the tube and the receiver, able to be moved up and down parallel to a direction of propagation of the X-rays, means for keeping the compression paddle in position in the radiation propagation direction, the compression paddle, in its compression position, being movable in at least one direction perpendicular to the direction of X-ray propagation and parallel to the contact edge of the image receiver. This allows a patient's breast to be rolled and presented to the image receiver in different positions thereby reducing ambiguities in possible detection of a lesion due to layers of tissue overlapping when images are taken.

摘要翻译： 一种具有X射线管，图像接收器，具有与患者接触的一个边缘的图像接收器，管与接收器之间的压缩桨，能够平行于 X射线的传播是用于将压缩桨保持在辐射传播方向上的位置的装置，压缩桨在其压缩位置可沿至少一个垂直于X射线传播方向的平行方向移动， 图像接收器的接触边缘。 这允许患者的乳房在不同的位置滚动并呈现给图像接收器，从而减少了在拍摄图像时由于组织层重叠而可能检测到病变的模糊性。

公开(公告)号：US06480566B2

公开(公告)日：2002-11-12

申请号：US10007810

申请日：2001-11-09

申请人： Serge Muller ,  Andreas Rick ,  Jean-Pierre Saladin

发明人： Serge Muller ,  Andreas Rick ,  Jean-Pierre Saladin

IPC分类号： A61B604

CPC分类号： A61B6/502 ,  A61B6/4423 ,  A61B6/481

摘要： Method and apparatus for medical radiology and, in particular, galactography in the field of mammography. The method of obtaining radiological images in galactography comprises acquiring of a first radiological image of the breast in a compressed state: introducing a contrast medium in a part of the breast; acquiring at least a second radiological image of the breast in the compressed state and with contrast medium; and partial or complete subtraction of the first image in relation to the second image, or vice versa. An apparatus for use of the method comprises means for maintaining a breast compressed or immobilized and means for holding a catheter or the like for introducing a contrast medium in the breast.

公开(公告)号：US06771738B2

公开(公告)日：2004-08-03

申请号：US10127079

申请日：2002-04-18

申请人： Luc Miotti ,  Serge Muller ,  Andreas Rick

发明人： Luc Miotti ,  Serge Muller ,  Andreas Rick

IPC分类号： G21K100

CPC分类号： A61B6/502 ,  A61B6/06 ,  A61B6/4291

摘要： Method and apparatus for a radiographic image of an object obtained by a radiography apparatus containing an X-ray emitter, in which an anti-scatter grid placed between the object and a radiographic image receiver is displaced, on rectilinear translation in its plane, when acquiring the images, between a starting position and an arrival position, according to a time displacement law of reference, at a greater rate of displacement in proximity to a starting position and to the arrival position. A measurement of the energy received in the form of X-radiation by the receiver is used to modify the rate of displacement of the grid at every instant.

摘要翻译： 通过包含X射线发射器的放射线照相设备获得的物体的放射线照相图像的方法和装置，其中放置在物体和放射线照相图像接收器之间的防散射栅格在其平面中被取代为直线平移时 根据时间位移定律，在起始位置和到达位置之间的图像，以更接近起始位置的位移速率和到达位置。 接收机以X射线形式接收的能量的测量用于修改每一时刻网格的位移速率。

公开(公告)号：US06714621B2

公开(公告)日：2004-03-30

申请号：US09900576

申请日：2001-07-06

申请人： Andreas Rick ,  Serge Muller

发明人： Andreas Rick ,  Serge Muller

IPC分类号： H05G164

CPC分类号： A61B6/502 ,  A61B6/481

摘要： Method and apparatus for examination of a breast, in which a contrast medium is injected in the breast to be examined, an X-ray beam is emitted in the direction of the breast; a plurality of digital images of the X-ray beam is taken after it has crossed the breast, and a representative image of the contrast produced in the tissues of the breast is calculated from the digital images.

摘要翻译： 用于检查乳房的方法和装置，其中造影剂注射到待检查的乳房中，X射线束沿着乳房的方向发射; 在穿过乳房之后拍摄X射线束的多个数字图像，并且从数字图像计算在乳房的组织中产生的对比度的代表性图像。