公开(公告)号：US20240336653A1

公开(公告)日：2024-10-10

申请号：US18007626

申请日：2021-05-19

Applicant: Shenzhen Turier Biotech Co., Ltd.

Inventor： Xianxing JIANG ,  Rui WANG ,  Nazi SONG

IPC: C07K7/08 ,  A61K38/00 ,  A61P1/16 ,  A61P11/00 ,  C07K7/64

CPC classification number: C07K7/08 ,  A61P1/16 ,  A61P11/00 ,  C07K7/64 ,  A61K38/00

Abstract: The present invention relates to peptide compound targeting elastin-derived peptides and use thereof. The peptide comprises a parent peptide represented by the following amino acid sequence: R1-Val-Xa2-Gly-Ser-Pro-Ser-Ala-Gln-Xa9-Xa10-Ala-Ser-Pro-Xa14, and is characterized by better biological activity, higher safety and stability, high synthesis yield, low cost, etc. The peptide compound may be used for treating hepatic fibrosis and fibrotic conditions accompanying hepatic disease as well as idiopathic pulmonary fibrosis and fibrotic conditions accompanying pulmonary disease.