公开(公告)号：US20130018433A1

公开(公告)日：2013-01-17

申请号：US13546820

申请日：2012-07-11

申请人： Shibaji Shome ,  Yanting Dong ,  Aaron R. McCabe

发明人： Shibaji Shome ,  Yanting Dong ,  Aaron R. McCabe

IPC分类号： A61N1/37

CPC分类号： A61N1/3712

摘要： An improved technique is described for dealing with the detection of fusion beats when capture verification is performed by a cardiac pacing device such as during a capture threshold determination procedure. Schemes for classifying heart beats may misclassify beats as fusion beats due to feature/m orphology changes in the test electrogram waveform that may occur even when capture is achieved.

摘要翻译： 描述了一种改进的技术，用于处理在心脏起搏装置执行捕获验证时，例如在捕获阈值确定过程期间的融合节拍的检测。 分类心脏跳动的方案可能将拍击误分为融合节拍，这是由于甚至在捕获时可能发生的测试电描绘图波形中的特征/ m形态变化。

公开(公告)号：US08565879B2

公开(公告)日：2013-10-22

申请号：US13071680

申请日：2011-03-25

申请人： Amy Jean Brisben ,  Shibaji Shome ,  Kenneth N. Hayes ,  Yanting Dong ,  Aaron R. McCabe ,  Scott A. Meyer ,  Kevin John Stalsberg

发明人： Amy Jean Brisben ,  Shibaji Shome ,  Kenneth N. Hayes ,  Yanting Dong ,  Aaron R. McCabe ,  Scott A. Meyer ,  Kevin John Stalsberg

IPC分类号： A61N1/08

CPC分类号： A61N1/36585 ,  A61N1/3712

摘要： An apparatus comprises a cardiac signal sensing circuit, a pacing therapy circuit, and a controller circuit. The controller circuit includes a safety margin calculation circuit. The controller circuit initiates delivery of pacing stimulation energy to the heart using a first energy level, changes the energy level by at least one of: a) increasing the energy from the first energy level until detecting that the pacing stimulation energy induces stable capture, or b) reducing the energy from the first energy level until detecting that the stimulation energy fails to induce capture, and continues changing the stimulation energy level until confirming stable capture or the failure of capture. The safety margin calculation circuit calculates a safety margin of pacing stimulation energy using at least one of a determined stability of a parameter associated with evoked response and a determined range of energy levels corresponding to stable capture or intermittent failure of capture.

摘要翻译： 一种装置包括心脏信号感测电路，起搏治疗电路和控制器电路。 控制器电路包括安全裕度计算电路。 控制器电路使用第一能级开始向心脏传送起搏刺激能量，通过以下至少一种来改变能量水平：a）从第一能量级增加能量直到检测到起搏刺激能量引起稳定的捕获，或 b）减少来自第一能级的能量，直到检测到刺激能量不能诱导捕获，并且继续改变刺激能量水平，直到确认捕获稳定或捕获失败为止。 安全裕度计算电路使用与诱发反应相关联的参数的确定的稳定性以及与捕获的稳定捕获或间歇性故障相对应的能量水平的确定范围中的至少一个来计算起搏刺激能量的安全裕度。

公开(公告)号：US09020596B2

公开(公告)日：2015-04-28

申请号：US13546820

申请日：2012-07-11

申请人： Shibaji Shome ,  Yanting Dong ,  Aaron R. McCabe

发明人： Shibaji Shome ,  Yanting Dong ,  Aaron R. McCabe

IPC分类号： A61N1/37

CPC分类号： A61N1/3712

摘要： An improved technique is described for dealing with the detection of fusion beats when capture verification is performed by a cardiac pacing device such as during a capture threshold determination procedure. Schemes for classifying heart beats may misclassify beats as fusion beats due to feature/morphology changes in the test electrogram waveform that may occur even when capture is achieved.

摘要翻译： 描述了一种改进的技术，用于处理在心脏起搏装置执行捕获验证时，例如在捕获阈值确定过程期间的融合节拍的检测。 分类心脏跳动的方案可能由于测试电描记图波形中的特征/形态变化而将节拍错误分类为融合节拍，即使实现捕获也可能发生。

公开(公告)号：US08401639B2

公开(公告)日：2013-03-19

申请号：US12724729

申请日：2010-03-16

申请人： Aaron R. McCabe ,  Shibaji Shome ,  Yanting Dong ,  Amy Jean Brisben

发明人： Aaron R. McCabe ,  Shibaji Shome ,  Yanting Dong ,  Amy Jean Brisben

IPC分类号： A61N1/39

CPC分类号： A61N1/3627 ,  A61N1/3712

摘要： Cardiac resynchronization therapy is delivered to a heart using an extended bipolar electrode configuration in accordance with programmed pacing parameters including a non-zero intraventricular delay. The extended bipolar electrode configuration comprises a left ventricular electrode defining a cathode of the extended bipolar electrode configuration and a right ventricular electrode defining an anode of the extended bipolar electrode configuration. A pace pulse is delivered to the left ventricular electrode and anodal stimulation of the right ventricle is detected based on the sensed response to the pace pulse.

摘要翻译： 使用扩展双极电极配置将心脏再同步治疗按照已编程的起搏参数（包括非零心室延迟）递送至心脏。 扩展双极电极配置包括限定扩展双极电极配置的阴极的左心室电极和限定延伸双极电极配置的阳极的右心室电极。 步速脉冲输送到左心室电极，并且基于感测到的对步速脉冲的响应来检测右心室的阳极刺激。

公开(公告)号：US20110245890A1

公开(公告)日：2011-10-06

申请号：US13071680

申请日：2011-03-25

申请人： Amy Jean Brisben ,  Shibaji Shome ,  Kenneth N. Hayes ,  Yanting Dong ,  Aaron R. McCabe ,  Scott A. Meyer ,  Kevin John Stalsberg

发明人： Amy Jean Brisben ,  Shibaji Shome ,  Kenneth N. Hayes ,  Yanting Dong ,  Aaron R. McCabe ,  Scott A. Meyer ,  Kevin John Stalsberg

IPC分类号： A61N1/08 ,  A61N1/362

CPC分类号： A61N1/36585 ,  A61N1/3712

摘要： An apparatus comprises a cardiac signal sensing circuit, a pacing therapy circuit, and a controller circuit. The controller circuit includes a safety margin calculation circuit. The controller circuit initiates delivery of pacing stimulation energy to the heart using a first energy level, changes the energy level by at least one of: a) increasing the energy from the first energy level until detecting that the pacing stimulation energy induces stable capture, or b) reducing the energy from the first energy level until detecting that the stimulation energy fails to induce capture, and continues changing the stimulation energy level until confirming stable capture or the failure of capture. The safety margin calculation circuit calculates a safety margin of pacing stimulation energy using at least one of a determined stability of a parameter associated with evoked response and a determined range of energy levels corresponding to stable capture or intermittent failure of capture.

摘要翻译： 一种装置包括心脏信号感测电路，起搏治疗电路和控制器电路。 控制器电路包括安全裕度计算电路。 控制器电路使用第一能级开始向心脏传送起搏刺激能量，通过以下至少一种来改变能量水平：a）从第一能量级增加能量直到检测到起搏刺激能量引起稳定的捕获，或 b）减少来自第一能级的能量，直到检测到刺激能量不能诱导捕获，并且继续改变刺激能量水平，直到确认捕获稳定或捕获失败为止。 安全裕度计算电路使用与诱发反应相关联的参数的确定的稳定性以及与捕获的稳定捕获或间歇性故障相对应的能量水平的确定范围中的至少一个来计算起搏刺激能量的安全裕度。

公开(公告)号：US20100262204A1

公开(公告)日：2010-10-14

申请号：US12724729

申请日：2010-03-16

申请人： Aaron R. McCabe ,  Shibaji Shome ,  Yanting Dong ,  Amy Jean Brisben

发明人： Aaron R. McCabe ,  Shibaji Shome ,  Yanting Dong ,  Amy Jean Brisben

IPC分类号： A61N1/368

CPC分类号： A61N1/3627 ,  A61N1/3712

摘要： Cardiac resynchronization therapy is delivered to a heart using an extended bipolar electrode configuration in accordance with programmed pacing parameters including a non-zero intraventricular delay. The extended bipolar electrode configuration comprises a left ventricular electrode defining a cathode of the extended bipolar electrode configuration and a right ventricular electrode defining an anode of the extended bipolar electrode configuration. A pace pulse is delivered to the left ventricular electrode and anodal stimulation of the right ventricle is detected based on the sensed response to the pace pulse.

摘要翻译： 使用扩展双极电极配置将心脏再同步治疗按照已编程的起搏参数（包括非零心室延迟）递送至心脏。 扩展双极电极配置包括限定扩展双极电极配置的阴极的左心室电极和限定延伸双极电极配置的阳极的右心室电极。 步速脉冲输送到左心室电极，并且基于感测到的对步速脉冲的响应来检测右心室的阳极刺激。

公开(公告)号：US08494619B2

公开(公告)日：2013-07-23

申请号：US12781411

申请日：2010-05-17

申请人： Theodore J. Schulte ,  Yanting Dong ,  Shibaji Shome ,  Abhilash Patangay

发明人： Theodore J. Schulte ,  Yanting Dong ,  Shibaji Shome ,  Abhilash Patangay

IPC分类号： A61B5/0452

CPC分类号： A61N1/3627 ,  A61B5/04525 ,  A61B5/7264 ,  A61N1/371 ,  G06F19/00

摘要： In an example, a cardiac rhythm management system includes an implantable physiological data monitor, a processor, a memory, and a display. The implantable physiological data monitor can be configured to monitor a plurality of cardiac responses. The processor can be configured to classify the cardiac response into one of at least three classes including pace-dominant, fusion, and pseudo-fusion. The processor can also be configured to calculate statistical information regarding the classified cardiac responses. In this example, the pace-dominant, fusion, and pseudo-fusion classes correspond to a cardiac response resulting from a corresponding electrostimulation. The memory is configured to store the classified cardiac responses and calculated statistical information for future use by the processor or for display. The display is configured to display the statistical information stored in the memory for diagnostic and device programming purposes.

摘要翻译： 在一个示例中，心律管理系统包括可植入的生理数据监视器，处理器，存储器和显示器。 可植入生理数据监视器可被配置为监视多个心脏反应。 该处理器可被配置为将心脏反应分类为至少三个类别中的一个，包括步调主导，融合和伪融合。 处理器还可以被配置为计算关于分类的心脏反应的统计信息。 在这个例子中，脚步显性，融合和伪融合类对应于由相应的电刺激产生的心脏响应。 存储器被配置为存储分类的心脏响应和计算的统计信息以供将来由处理器使用或用于显示。 显示器被配置为显示存储在存储器中用于诊断和设备编程目的的统计信息。

公开(公告)号：US20110264158A1

公开(公告)日：2011-10-27

申请号：US13094416

申请日：2011-04-26

申请人： Yanting Dong ,  Allan C. Shuros ,  Jiang Ding ,  Scott A. Meyer ,  Shibaji Shome

发明人： Yanting Dong ,  Allan C. Shuros ,  Jiang Ding ,  Scott A. Meyer ,  Shibaji Shome

IPC分类号： A61N1/362

CPC分类号： A61N1/371 ,  A61B5/0031 ,  A61B5/04525 ,  A61B5/7264 ,  A61N1/3712 ,  A61N1/37247

摘要： This document discusses, among other things, a system and method for generating a stimulation energy to provide His-bundle stimulation for a cardiac cycle, receiving electrical information from the heart over at least a portion of the cardiac cycle, determining a characteristic of at least a portion of the received electrical information for the cardiac cycle, and classifying the cardiac cycle using the determined characteristic.

摘要翻译： 本文件尤其涉及用于产生刺激能量以提供心跳周期的His束刺激的系统和方法，在心脏周期的至少一部分上从心脏接收电信息，确定至少一个特征 所接收的用于心动周期的电信息的一部分，并且使用所确定的特征对心动周期进行分类。

公开(公告)号：US20100305646A1

公开(公告)日：2010-12-02

申请号：US12781411

申请日：2010-05-17

申请人： Theodore J. Schulte ,  Yanting Dong ,  Shibaji Shome ,  Abhilash Patangay

发明人： Theodore J. Schulte ,  Yanting Dong ,  Shibaji Shome ,  Abhilash Patangay

IPC分类号： A61N1/365

CPC分类号： A61N1/3627 ,  A61B5/04525 ,  A61B5/7264 ,  A61N1/371 ,  G06F19/00

摘要： In an example, a cardiac rhythm management system includes an implantable physiological data monitor, a processor, a memory, and a display. The implantable physiological data monitor can be configured to monitor a plurality of cardiac responses. The processor can be configured to classify the cardiac response into one of at least three classes including pace-dominant, fusion, and pseudo-fusion. The processor can also be configured to calculate statistical information regarding the classified cardiac responses. In this example, the pace-dominant, fusion, and pseudo-fusion classes correspond to a cardiac response resulting from a corresponding electrostimulation. The memory is configured to store the classified cardiac responses and calculated statistical information for future use by the processor or for display. The display is configured to display the statistical information stored in the memory for diagnostic and device programming purposes.

摘要翻译： 在一个示例中，心律管理系统包括可植入的生理数据监视器，处理器，存储器和显示器。 可植入生理数据监视器可被配置为监视多个心脏反应。 该处理器可被配置为将心脏反应分类为至少三个类别中的一个，包括步调主导，融合和伪融合。 处理器还可以被配置为计算关于分类的心脏反应的统计信息。 在这个例子中，脚步显性，融合和伪融合类对应于由相应的电刺激产生的心脏响应。 存储器被配置为存储分类的心脏响应和计算的统计信息以供将来由处理器使用或用于显示。 显示器被配置为显示存储在存储器中用于诊断和设备编程目的的统计信息。

公开(公告)号：US08306622B2

公开(公告)日：2012-11-06

申请号：US12892378

申请日：2010-09-28

申请人： Shantha Arcot-Krishnamurthy ,  Shibaji Shome ,  Yanting Dong

发明人： Shantha Arcot-Krishnamurthy ,  Shibaji Shome ,  Yanting Dong

IPC分类号： A61N1/00

CPC分类号： A61N1/371 ,  A61N1/3627 ,  A61N1/3684

摘要： A method and device to detect and compare changes in atrial rate and morphology can be used to identify left atrial sense and capture, such as from a quadripolar or other lead located in or around the coronary sinus.

摘要翻译： 用于检测和比较心房率和形态变化的方法和装置可用于鉴定左心房感和捕获，例如来自位于冠状窦内或周围的四极或其他导联。